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Study Ties Genes to Lower Urinary Tract Symptoms, Prostate Cancer Risk
Posted 6 days ago by Drugs.com
TUESDAY, May 22 – Certain gene variants linked to prostate cancer may make men more susceptible to lower urinary tract symptoms, according to a new study. On the other hand, a different gene variant might protect against those symptoms, the study found. Researchers from the Feinberg School of Medicine at Northwestern University in Chicago identified 38 genetic sequence variants linked to prostate cancer risk in nearly 2,000 healthy, white men enrolled in a prostate cancer screening study. The men completed questionnaires on the severity of their lower urinary tract symptoms, their age and whether they took medications used to treat enlarged prostate (benign prostatic hyperplasia). Four of the genetic variants were associated with severity of urinary tract symptoms, even after taking into account other genetic variations, age and medication use. The study was scheduled to be presented ... Read more
Related support groups: Benign Prostatic Hyperplasia (BPH), Prostate Cancer, Urinary Retention
Men Can Still Ask for PSA Test, and Some Should, Doctors Say
Posted 6 days ago by Drugs.com
TUESDAY, May 22 – Although a U.S. advisory panel no longer recommends that men routinely undergo prostate cancer screening with a PSA blood test, men should ask their doctors for the exam if they're uncomfortable without monitoring, health experts say. Urologists and cancer experts dismissed the idea that the U.S. Preventive Services Task Force's criticism of the PSA test will set a man's personal agenda or interfere with doctor-patient relationships. They acknowledged, however, that health insurers are likely to take notice of the new recommendation, released May 22 in the journal Annals of Internal Medicine, and potentially alter coverage of the screening test. In abandoning earlier guidelines that called for screening to start at 50, the task force said the PSA test does more harm than good, resulting in overdiagnosis of many slow-growing cancers while prompting aggressive treatment ... Read more
Related support groups: Prostate Cancer
Do Bald Men Face Higher Risk of Prostate Cancer?
Posted 6 days ago by Drugs.com
TUESDAY, May 22 – Got hair? If you don't, you might have a higher risk of prostate cancer, a preliminary study suggests. Researchers are reporting that bald men who underwent biopsies of the prostate were more likely to have cancer than were those with more hair on their heads. "Bald men should be aware that they may benefit from being screened earlier and perhaps, if necessary, from being biopsied sooner," said study author Dr. Neil Fleshner, a professor of surgical urology at the University of Toronto. "In the study, the more bald people were, the more likely they were to have prostate cancer. We're 95 percent sure this is real." However, not all doctors are ready to embrace the study's conclusions. The possible association between male pattern baldness and prostate cancer has been considered in previous studies. Although the precise mechanism isn't understood, researchers think male ... Read more
Related support groups: Prostate Cancer, Alopecia, Androgenetic Alopecia
U.S. Advisers Say 'No' to Routine PSA Tests for Prostate Cancer
Posted 7 days ago by Drugs.com
MONDAY, May 21 – In a highly anticipated move sure to unleash heated debate, a prominent U.S. government advisory panel is recommending that men of all ages no longer be screened for prostate cancer by undergoing the prostate-specific antigen (PSA) blood test. The U.S. Preventive Services Task Force, an independent group of medical experts in prevention and evidence-based medicine, said PSA screening results in overdiagnosis of prostate cancer and unnecessary treatment that can leave men impotent and incontinent. This final recommendation comes seven months after the task force drafted a report giving a "D" rating for the PSA blood test. Previous guidelines had stated that most men should undergo screening beginning at age 50. "Some may say that by rating the test a 'D' we're taking away the possibility of an informed decision, but we don't want that to be the case," said task force ... Read more
Related support groups: Prostate Cancer
Advanced Prostate Cancer Drug May Help at Earlier Stage
Posted 12 days ago by Drugs.com
WEDNESDAY, May 16 – A drug approved to treat advanced prostate cancer appears to help men who have localized high-risk prostate cancer if given before surgery. Adding Zytiga (abiraterone) to conventional hormonal treatments eliminated or nearly eliminated the prostate cancer in one-third of men with this often-lethal form, according to new research to be presented at next month's annual meeting of the American Society of Clinical Oncology (ASCO) in Chicago. "This is one of the first – if not the first – study to show that you can make prostate cancer in the prostate gland itself disappear in a reproducible number of patients," ASCO official Dr. Nicholas Vogelzang said at a Wednesday press conference. Commenting on the findings, Dr. Jay Brooks, chairman of hematology/oncology at Ochsner Health System in Baton Rouge, said, "This is exciting. It's a novel way to eliminate cancer before ... Read more
Related support groups: Prostate Cancer, Zytiga, Abiraterone
Healthy Behaviors Extend Life After Cancer, Experts Say
Posted 26 Apr 2012 by Drugs.com
THURSDAY, April 26 – A healthy lifestyle – including eating right, exercising and maintaining normal weight – can boost the odds of long-term cancer survival, especially for breast, colorectal or prostate cancer, according to new recommendations from the American Cancer Society. About one in 25 Americans is a cancer survivor. "Many ask, 'How can I keep the cancer from coming back?' " said Colleen Doyle, the cancer society's director of nutrition and physical activity. Cancer survivors often are advised to adopt healthy behaviors, including eating lots of fruits, vegetables, whole grains and lean protein; fitting in walking or other aerobic activity most days of the week; and keeping weight within a normal range, Doyle said. Research has shown that those steps can help prevent cancer, but there was little research showing that a healthy lifestyle could keep cancer from recurring, or ... Read more
Related support groups: Breast Cancer, Prostate Cancer, Colorectal Cancer
Prostate Cancer Screening Guidelines Often Not Followed: Study
Posted 24 Apr 2012 by Drugs.com
TUESDAY, April 24 – In 2008, the U.S. Preventive Services Task Force recommended against testing for prostate cancer in men aged 75 and older, but new research finds that almost 44 percent of these men are still being screened. Before the 2008 guidelines were set, about 43 percent of men in this age group opted for prostate-specific antigen (PSA) tests, but the task force found that testing had no effect on longevity and could result in overtreatment with adverse consequences. Meanwhile, the task force drafted a new set of guidelines last October that are even more critical of PSA testing, suggesting it may not have any value for men of any age. "Patients and providers did not adjust their screening behavior following the last major United States Preventive Services Task Force recommendation, and the effect of the upcoming guideline needs to be monitored," said study author Dr. Sandip ... Read more
Related support groups: Prostate Cancer
Researchers Find Genes Linked to Aggressive Prostate Cancer
Posted 9 Apr 2012 by Drugs.com
MONDAY, April 9 – The discovery of two inherited genetic variations may help doctors identify men at greater risk for aggressive prostate cancer, a new study suggests. A man's risk for the disease could triple or even quadruple depending on the genetic variant they have, according to the researchers from Weill Cornell Medical College in New York City and elsewhere. "We used to think that only genes that made proteins were responsible for disease, but this study shows us that there is inherited information in the non-coding areas of the genome that appear to play a strong role in development of cancer," study co-author Dr. Mark Rubin, professor of oncology in pathology, said in a Weill Cornell news release. Having a family history of prostate cancer is the strongest risk factor for the disease. As a result, the researchers set out to find DNA that is deleted or duplicated in the genetic ... Read more
Related support groups: Prostate Cancer
New Scanning Technology Might Help Guide Prostate Cancer Care
Posted 1 Apr 2012 by Drugs.com
SATURDAY, March 31 – A noninvasive scan might someday help doctors track the progress of prostate cancer and help guide treatment, researchers report. The imaging tool, known as a prostate cancer-specific radiotracer, has so far only been tested successfully in mice. But a team from Memorial Sloan-Kettering Cancer Center in New York City said the technology could help identify cases where prostate cancer has spread to the bone. Radiotracers work by injecting a small amount of a compound tagged with a radionuclide into patients. Using positron emission tomography – also known as a PET scan – doctors are then able to better visualize tumors and tumor spread. In studies involving mice with prostate cancer, the researchers had the radiotracer hone in on prostate-specific antigen (PSA), the same prostate cancer marker used in the PSA test. They found that the PSA gravitated to tissues ... Read more
Related support groups: Prostate Cancer
U.S. Cancer Death Rates Continue to Fall: Report
Posted 28 Mar 2012 by Drugs.com
WEDNESDAY, March 28 – Deaths from cancer in the United States continue to decline, health officials report. However, deaths from some types of cancers are on the increase and racial disparities remain in cancer deaths and diagnosis, according to the report from the U.S. Centers for Disease Control and Prevention. "This annual report shows that a lot of the positive momentum we have seen in cancer control has continued," said report co-author Dr. Marcus Plescia, director of CDC's Division of Cancer Prevention and Control. "We are still seeing decreases in the incidence in death rates for many cancers and particularly for many of the most common cancers." The focus of this report was obesity's impact on cancer. "That's important, because we don't think the public is aware of that," Plescia said. For six cancers, there is good evidence of a relationship between obesity and cancer: ... Read more
Related support groups: Obesity, Cancer, Breast Cancer, Prostate Cancer, Smoking Cessation, Lung Cancer, Colorectal Cancer, Pancreatic Cancer, Skin Cancer, Melanoma
Study Finds PSA Testing Cuts Prostate Cancer Death Risk
Posted 14 Mar 2012 by Drugs.com
WEDNESDAY, March 14 – Adding another perspective to one of the most controversial and confounding issues in medicine, a new European study reports that men who received routine prostate-specific antigen (PSA) tests to check for signs of prostate cancer were 30 percent less likely to die from the disease. But the big picture isn't simple enough for the new research to solve once and for all the question of whether PSA testing helps men. "There is little doubt that a man who undergoes testing will have about a 30 percent less chance of dying from prostate cancer," said the study's lead author, Dr. Fritz Schroder, professor of urology at Erasmus University in Rotterdam, Netherlands. "On the other side, there's a 30 percent chance that a cancer found is insignificant and the patient may be confronted with the side effects of treatment unnecessarily." Schroder is referring to the major ... Read more
Related support groups: Prostate Cancer
Circumcision Linked to Lower Risk for Prostate Cancer, Study Finds
Posted 12 Mar 2012 by Drugs.com
MONDAY, March 12 – Men who have prostate cancer are less likely to be circumcised, according to new research. The researchers suggest a possible reason is that circumcision reduces the risk of sexually transmitted diseases that may contribute to prostate tumors. The study doesn't confirm that circumcision directly lowers the risk of prostate cancer, and the study lead author cautioned that the findings shouldn't play a role in the decisions of parents about the sometimes-controversial procedure. Still, the results fit in with existing knowledge about how cancer develops, said study author Dr. Jonathan Wright, a urologic oncologist at the Fred Hutchinson Cancer Research Center at the University of Washington in Seattle. "It helps us to understand how cancers develop and ultimately learn how to combat the disease," he said. Circumcision is the removal of the foreskin that covers the ... Read more
Related support groups: Prostate Cancer, Sexually Transmitted Diseases
Older Prostate Cancer Patients Might Be Overtreated: Study
Posted 29 Feb 2012 by Drugs.com
WEDNESDAY, Feb. 29 – Seniors may not benefit from prostate cancer treatment, according to a new study that found aggressive therapy has become more common among men with short life expectancies and less aggressive forms of the disease. "Treatment can do more harm than good in some instances," senior study author Dr. Cary Gross, an associate professor of internal medicine at the Yale School of Medicine, said in a university news release. "Among men who are older and have less aggressive forms of prostate cancer, their cancer is unlikely to progress or cause them harm in their remaining years." The researchers used Medicare records to examine information on more than 39,000 men with prostate cancer aged 67 and older. The study, published Feb. 27 in Archives of Internal Medicine, found increasingly intensive treatment among older patients puts them at risk for complications and reduced ... Read more
Related support groups: Prostate Cancer
Nerve-Sparing Prostate Surgery Helps Men Retain Sexual Function
Posted 16 Feb 2012 by Drugs.com
THURSDAY, Feb. 16 – Most men who have surgery for prostate cancer can still achieve orgasm if the nerves that surround their prostate gland are not removed, according to a new study. Researchers from Cornell University say a man's age and the number of his nerves that are spared will play a role in his ability to climax after surgery. The study followed 408 men who underwent a procedure to remove their prostate, known as robot-assisted laparoscopic radical prostatectomy, between 2005 and 2007 for an average of three years. Men had mean age of 60 years and all were able to have an orgasm before the procedure. Seventy-four percent of the men were able to have their nerves spared bilaterally, or on both sides. Of those men, 91 percent experienced no change in their ability to achieve orgasm following the surgery. About 13 percent of the men had their nerves spared on only one side. Of ... Read more
Related support groups: Prostate Cancer
Heart Disease May Be Risk Factor for Prostate Cancer
Posted 9 Feb 2012 by Drugs.com
THURSDAY, Feb. 9 – Heart disease may be a risk factor for prostate cancer, a new study suggests. If this link is confirmed in future research, it means that lifestyle changes that reduce heart disease risk – such as weight loss, exercise and a healthy diet – may also protect men against prostate cancer, the Duke Cancer Institute researchers said. "What's good for the heart may be good for the prostate," study author Dr. Jean-Alfred Thomas II, a postdoctoral fellow in the division of urology, said in a Duke Medicine news release. He and his colleagues analyzed data from 6,390 men in a four-year clinical trial testing a drug's effectiveness in reducing prostate cancer risk. Of those men, 547 reported a history of coronary artery disease before the start of the trial. The Duke researchers found that men with coronary artery disease had a 35 percent greater risk of developing prostate ... Read more
Related support groups: Heart Disease, Prostate Cancer
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