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Peripheral Arterial Disease Blog

Related terms: Peripheral Artery Disease, Peripheral Vascular Disease

Poor More Prone to Leg Circulation Trouble

Posted 14 Jul 2014 by Drugs.com

FRIDAY, July 11, 2014 – People with the lowest incomes may have a higher risk for a circulatory condition called peripheral artery disease (PAD), a new study suggests. People with PAD have narrowing of the arteries that supply blood to the limbs, most often the legs. The condition causes leg pain and is often an indicator of narrowing of the arteries throughout the body. People with PAD have a higher risk for heart disease and stroke. Researchers analyzed data from nearly 6,800 people with PAD who took part in the U.S. National Health and Nutrition Examination Survey from 1999 to 2004. They found that those with low incomes were significantly more likely to have the disease. People with the lowest income levels were more than twice as likely to have PAD as those with the highest income and education levels, according to the study published online recently in the journal Circulation: ... Read more

Related support groups: Peripheral Arterial Disease

Could Dark Chocolate Help Ease Poor Leg Circulation?

Posted 3 Jul 2014 by Drugs.com

WEDNESDAY, July 2, 2014 – The antioxidants contained in dark chocolate might help people suffering from reduced blood flow to their legs, researchers from Italy report. In a small study, people with artery problems in their legs walked a little longer and farther right after eating a bar of dark chocolate, the researchers said. Dark chocolate is rich in antioxidants called polyphenols. The researchers believe polyphenols improve blood flow to the legs by affecting biochemicals that prompt arteries to widen. "Our body secretes chemicals that naturally dilate blood vessels in response to certain stimuli, improving the blood flow to certain areas," said Dr. Richard Chazal, vice president of the American College of Cardiology. "Some of the chemicals inside dark chocolate could affect the way these enzymes are metabolized in the body," suggested Chazal, who was not involved with the study. ... Read more

Related support groups: Peripheral Arterial Disease

Walking at Home Can Help Boost Poor Circulation in Legs, Study Shows

Posted 25 May 2014 by Drugs.com

WEDNESDAY, May 21, 2014 – A home-based walking program benefits people with poor blood circulation in their legs, a new study finds. The study included patients with peripheral artery disease (PAD), a narrowing of the arteries that can cause leg pain and hinder walking ability. Previous research found that supervised exercise programs can improve walking and reduce the symptoms of PAD, but this study is the first to examine the effects of a home-based workout regimen. There were 81 patients who took part in a program that trained and encouraged them to walk at home, and a control group of 87 patients who received only general health information. The participants in the home walking program were told to try to walk at least five days a week, building up to 50 minutes a day. If they experienced leg pain, they were to rest until their legs were comfortable again and then resume walking. ... Read more

Related support groups: Peripheral Arterial Disease

Dissolving 'Scaffolds' Could Help Treat Leg Artery Disease

Posted 22 Jan 2014 by Drugs.com

WEDNESDAY, Jan. 22, 2014 – Drug-coated "scaffolds" that are placed in the arteries and then melt away over time could offer a new treatment for people with painfully clogged leg arteries, an early study suggests. Researchers found that the experimental devices eased leg pain in 35 patients with peripheral artery disease. People with the condition have artery-clogging "plaques" impeding blood flow to the legs. Before treatment, 57 percent of the patients had severe pain when they walked; one month after treatment, none of them did. The findings, scheduled for presentation Wednesday at the International Symposium on Endovascular Therapy, in Miami, should be considered preliminary until published in a peer-reviewed medical journal. And experts cautioned that it's not clear how these devices compare with the current treatment for more severe cases of peripheral artery disease – namely, ... Read more

Related support groups: Peripheral Arterial Disease

Higher Spending on Poor Leg Circulation May Not Pay Off

Posted 21 Nov 2013 by Drugs.com

WEDNESDAY, Nov. 20, 2013 – Poor circulation in the legs, a condition called peripheral artery disease (PAD), affects many Americans and can become so serious it leads to amputation. But a new study finds wide hospital-to-hospital variance in spending on PAD, with no significant difference in amputation rates. "Medicare spending on patients with severe PAD varies more than twofold across the United States," wrote a team led by Dr. Philip Goodney of the Dartmouth-Hitchcock Medical Center. In background information in the study, the researchers noted that in recent years, care aimed at preventing amputation has become increasingly costly due to the rising use of less-invasive "revascularizations" – treatments used to improve blood flow. According to Goodney's team, hospitals in regions that spent the most on PAD patients often ordered these lower-limb treatments in the year prior to an ... Read more

Related support groups: Peripheral Arterial Disease

Peripheral Artery Disease on the Rise Worldwide

Posted 1 Aug 2013 by Drugs.com

THURSDAY, Aug. 1 – The number of people with peripheral artery disease – a debilitating condition that can lead to heart attack and stroke – rose nearly 24 percent, from 164 million to 202 million worldwide, over the past decade. A new analysis from 2000 to 2010 found that although rates of peripheral artery disease are increasing in all parts of the world, 70 percent (140 million) of sufferers live in low- or middle-income countries, mainly in southeast Asia (54 million) and western Pacific regions (46 million). Peripheral artery disease is caused by plaque accumulation in arteries that carry blood to the limbs. The condition increases the risk of heart attack and stroke and severely limits walking ability. The analysis of published studies on peripheral artery disease also revealed that the number of people with the condition increased nearly 29 percent in low-income countries and ... Read more

Related support groups: Peripheral Arterial Disease

Home Treadmills May Help People With Poor Leg Circulation

Posted 2 Jul 2013 by Drugs.com

TUESDAY, July 2 – A home-based treadmill exercise program improved walking speed and endurance in people with poor circulation in the legs, a condition known as peripheral artery disease (PAD). That's the finding of a study that included nearly 200 PAD patients whose change in performance in a six-minute walk was measured over six months. Study patients who did the home-based treadmill exercise program increased their walking distance over six minutes by nearly 150 feet, compared with a decline of 36 feet among patients in a "control" group who did not do the exercise program. Participants in the exercise group also improved their maximum treadmill walking time by nearly a minute and a half, while the change in the control group was about 30 seconds, according to Dr. Mary McDermott, of the Northwestern University Feinberg School of Medicine, and colleagues. The investigators determined ... Read more

Related support groups: Peripheral Arterial Disease

Drug May Make Walking Easier for People With Artery Disease

Posted 5 Feb 2013 by Drugs.com

TUESDAY, Feb. 5 – The blood pressure drug ramipril may make walking a bit easier for people with clogged leg arteries, new study results suggest. Researchers found that of 212 people with peripheral artery disease (PAD), those given ramipril every day for nearly six months were faring better on their feet than those on inactive placebo pills. On average, they could walk on a treadmill 4 minutes longer, and got an extra 75 seconds of pain-free walking. That might not sound like a big difference. But it beats the benefits of the two drugs approved in the United States for improving PAD patients' ability to walk, according to Dr. Mary McGrae McDermott, a professor of medicine at Northwestern University Feinberg School of Medicine in Chicago. It's also similar to the effects of supervised exercise therapy – another standard PAD treatment, said McDermott, who wrote an editorial published ... Read more

Related support groups: Ramipril, Peripheral Arterial Disease, Trental, Cilostazol, Altace, Pletal, Pentoxifylline, Pentoxil

Lifestyle Affects Outcome of Peripheral Artery Procedure: Study

Posted 26 Dec 2012 by Drugs.com

WEDNESDAY, Dec. 26 – Patients with blocked leg arteries are less likely to suffer complications after a procedure to open their arteries if they quit smoking and take aspirin and cholesterol-lowering statins, a new study indicates. However, too few patients take such steps to relieve leg pain and cramping associated with peripheral artery disease, also known as PAD, according to the researchers. The new study of more than 1,300 patients found that only about 47 percent of them did not smoke and were taking aspirin and a statin – drugs that can reduce blood clots and improve blood flow – when they were admitted to hospital for a peripheral vascular intervention, such as angioplasty, which is performed to open blocked leg arteries and improve blood flow. When they were discharged from hospital, 71 percent of the patients were taking aspirin and a statin and either did not smoke or ... Read more

Related support groups: Aspirin, Lipitor, Simvastatin, Crestor, Pravastatin, Atorvastatin, Zocor, Lovastatin, Rosuvastatin, Red Yeast Rice, Ecotrin, Livalo, Pravachol, Peripheral Arterial Disease, Bayer Aspirin, Lescol, Bufferin, Lescol XL, Low Dose ASA, Mevacor

Drug-Eluting Stent Approved for Peripheral Arterial Disease

Posted 15 Nov 2012 by Drugs.com

THURSDAY, Nov. 15 – The Zilver PTX Drug-Eluting Peripheral Stent has been approved by the U.S. Food and Drug Administration to treat peripheral arterial disease of a particular artery in the thigh. An arterial stent is a hollow mesh tube that's used to prop open an artery that's narrowed or clogged. This stent is coated with a drug that helps prevent the artery from narrowing again. Peripheral arterial disease (PAD) occurs when fatty material called plaque builds up on the artery wall, affecting oxygenated blood flow to the body. Symptoms could include leg pain, skin ulcers or gangrene, the FDA said in a news release. The safety and effectiveness of the stent were evaluated in a clinical study of 479 people. After one year, 83 percent of narrowed arteries treated with the new stent were still open, compared with 33 percent in a control group, the FDA said. The most common adverse ... Read more

Related support groups: Peripheral Arterial Disease

Chemical in Household Products May Be Linked to Heart Disease: Study

Posted 4 Sep 2012 by Drugs.com

TUESDAY, Sept. 4 – Exposure to a chemical used in some common household products may be associated with heart troubles and peripheral artery disease, a new study suggests. The chemical perfluorooctanoic acid (PFOA) – which is widely used to make products such as food packaging, paper and textile coatings, polishes and lubricants – is detectable in the blood of more than 98 percent of people in the United States, according to previous research. In this study, a team at the West Virginia University School of Public Health looked at data from more than 1,200 people and found that increasing blood levels of PFOA were associated with the presence of heart and artery disease. This association appeared to be independent of other disease risk factors such as age, sex, race/ethnicity, smoking, body-mass index, diabetes, high blood pressure and cholesterol levels. The study was published ... Read more

Related support groups: Heart Disease, Peripheral Arterial Disease

Angioplasty May Be Risky for Those With Poor Leg Circulation

Posted 9 May 2012 by Drugs.com

WEDNESDAY, May 9 – People with peripheral artery disease have an increased short- and long-term risk of death after undergoing a procedure to open clogged heart arteries, a new study finds. Peripheral artery disease (PAD) is a build-up of plaque in the blood vessels of the legs and organs of the body. These cholesterol blockages can interfere with blood flow and cause pain and cramping in the legs, sores that don't heal properly, abdominal pain, high blood pressure and other health problems. For the study, researchers looked at data from nearly 2,500 heart disease patients who underwent percutaneous coronary intervention (which includes both angioplasty and stenting) to open clogged heart arteries. Of those patients, 7 percent also had peripheral artery disease. The death rate while patients were in hospital immediately after the procedure was much higher for those with peripheral ... Read more

Related support groups: Peripheral Arterial Disease

Depression Linked to Higher Odds for Poor Leg Circulation

Posted 20 Apr 2012 by Drugs.com

FRIDAY, April 20 – Depressed people may be at higher risk for the debilitating circulatory condition known as peripheral artery disease (PAD), a new study suggests. PAD is due to a narrowing of the arteries in the legs and pelvis. It was known that depression is a risk factor for the constriction of heart arteries, but its link with PAD specifically was unclear. In this study, researchers led by Marlene Grenon of the University of California, San Francisco, Medical Center examined data on more than a thousand men and women who were followed for about seven years. At the start of the study, PAD was present in 12 percent of the participants with depression and in 7 percent of those without depression. During the seven-year follow-up, PAD-related events occurred in 9 percent of participants with depression and in 6 percent of those without depression, the researchers said. One expert ... Read more

Related support groups: Depression, Peripheral Arterial Disease

Dissolvable Heart Artery Stents Appear Safe in Study

Posted 16 Apr 2012 by Drugs.com

MONDAY, April 16 – New long-term research now suggests that fully biodegradable stents are safe to use in heart arteries. Reporting in the April 16 issue of Circulation, Japanese researchers said a 10-year study has shown the biodegradable Igaki-Tamai stent, made of a cornstarch-based material, dissolves into the artery wall, leaving no permanent foreign material in an artery and reducing the occurrence of an in-stent blood clot. According to the study, survival rates from all causes was 87 percent and rates of major heart-related complications were similar to those seen with metal stents. Stents, the tiny mesh tubes inserted into heart arteries to keep open and allow blood to flow to the heart, are far from fail-safe. New blockages can – and do – occur. So scientists have been trying to develop new stents, including ones coated with blood-thinning medications. Metal stents, ... Read more

Related support groups: Coronary Artery Disease (CAD), Peripheral Arterial Disease

Aspirin as Good as Plavix for Poor Leg Circulation: Study

Posted 21 Feb 2012 by Drugs.com

TUESDAY, Feb. 21 – Aspirin works as well as Plavix in patients with blocked leg arteries, a new European study finds. People with the condition, called peripheral artery disease, often suffer from intermittent claudication, which is pain while walking because of decreased blood supply to the legs. Animal experiments had suggested that aspirin might block the growth of blood vessels that bypass blockages and help get more blood to leg tissue, the Swiss and German researchers said. "Once again, we have shown that what happens in animals doesn't translate to humans," said Dr. Juan Zambrano, an assistant professor of cardiovascular medicine, coronary/endovascular and stem cell therapies at the University of Miami Miller School of Medicine. Patients suffering from peripheral artery disease are also at increased risk of heart attack and stroke from blood clots traveling from the legs to the ... Read more

Related support groups: Aspirin, Plavix, Clopidogrel, Ecotrin, Peripheral Arterial Disease, Bayer Aspirin, Intermittent Claudication, Bufferin, Low Dose ASA, Ascriptin Enteric, Easprin, ZORprin, Aspergum, St Joseph Aspirin, Buffered Aspirin, Norwich Aspirin, Migralex, Bayer Childrens Aspirin, Gennin-FC, Aspir-Low

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Raynaud's Syndrome, Intermittent Claudication, Arterial Thrombosis, Erythromelalgia, Thromboangiitis Obliterans, Peripheral Arteriography, Cardiovascular Conditions and Disorders

Related Drug Support Groups

Plavix, clopidogrel