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Drugs May Help Relieve Restless Legs Syndrome

Posted 4 Mar 2013 by Drugs.com

MONDAY, March 4 – People suffering from restless legs syndrome may find some relief by taking one of several drugs approved to treat the condition, a new review confirms. The medications, which include Requip (ropinirole), levodopa, Neurontin (gabapentin) and Lyrica (pregabalin), appear to reduce symptoms of the syndrome in more than 60 percent of patients, researchers report. The first two drugs raise dopamine levels in the body, and the last two drugs reduce the amount of calcium reaching brain cells and trigger the production of other chemicals that help reduce pain. Dopamine is a brain chemical that regulates movement and mood. "Physicians and patients now have better information on the effectiveness and harms of two types of drug treatments for patients with at least moderately severe restless legs symptoms in which to guide treatment choices," said review author Dr. Timothy Wilt, ... Read more

Related support groups: Gabapentin, Lyrica, Neurontin, Restless Legs Syndrome, Pregabalin, Requip, Ropinirole, Levodopa, Gralise, Horizant, Requip XL, Requip Starter Kit, Gabarone, Repreve, Fanatrex, ReQuip Follow on Pack, Dopar, ReQuip Starter Pack, Larodopa

Chronic Cough Responds to Epilepsy Drug, Study Finds

Posted 28 Aug 2012 by Drugs.com

TUESDAY, Aug. 28 – A drug commonly used to control epileptic seizures and pain, gabapentin, also appears to ease hard-to-treat chronic coughs, a new study says. Chronic cough affects 11 percent to 16 percent of the population, the researchers report. The exact cause is unknown, but it might relate to a malfunction in a part of the brain that causes coughing. Gabapentin works by suppressing that "cough center," they said. "It is effective and well-tolerated, and may provide significant relief and respite from such a physically and psychologically disabling condition," said lead researcher Nicole Ryan, a clinical research scientist at the University of Newcastle in Australia. "Gabapentin is a real treatment option for people with refractory chronic cough, especially for those with features of central sensitization." People with this kind of cough feel the need to cough when there is no ... Read more

Related support groups: Gabapentin, Cough, Neurontin, Gralise, Horizant, Gabarone, Fanatrex

Prescription Meds Can Put on Unwanted Pounds

Posted 2 Mar 2012 by Drugs.com

FRIDAY, March 2 – Medications taken by millions of Americans for mood disorders, high blood pressure, diabetes and other chronic conditions can have an unhealthy side effect: weight gain. While other choices exist for some types of drugs, adjusting medications is not simply a matter of switching, said Ryan Roux, chief pharmacy officer with the Harris County Hospital District, in Houston. In the late 1990s, Dr. Lawrence Cheskin conducted early research on prescription medicines and obesity. "Some medicines make an early, noticeable difference, causing patients to become ravenously hungry, while changes are subtle for others. A few months taking them and you've gained 10 pounds," said Cheskin, now director of the Johns Hopkins Weight Management Center, in Baltimore. To help increase awareness, Roux and his pharmacist group have compiled a list of "weight-promoting" and "weight-neutral or ... Read more

Related support groups: Bipolar Disorder, High Blood Pressure, Zoloft, Diabetes, Type 2, Wellbutrin, Plan B, Prozac, Prednisone, Gabapentin, Seroquel, Metformin, Hypertension, Sprintec, Paxil, Mirena, Implanon, Lamictal, Provera, NuvaRing, Metoprolol

New Guidelines Issued for Common Tremor Disorder

Posted 19 Oct 2011 by Drugs.com

WEDNESDAY, Oct. 19 – An antiseizure drug called primidone (Mysoline) and a high blood pressure drug called propranolol (Inderal) are the most effective medicines to treat shaking in people with essential tremor, according to an updated treatment guideline from the American Academy of Neurology. Essential tremor, which affects about 10 million people in the United States, is the most common type of tremor disorder and is often mistaken with other movement disorders such as Parkinson's disease. The condition usually starts after age 40 and affects the hands, head and voice. It can cause difficulties with daily activities such as eating, writing, shaving and sewing. Along with primidone and propranolol, other helpful medicines include the antiseizure drugs gabapentin (Fanatrex, Neurontin) and topiramate (Topamax), the high blood pressure drugs atenolol (Tenormin) and sotalol (Betapace, ... Read more

Related support groups: Xanax, Gabapentin, Neurontin, Topamax, Atenolol, Alprazolam, Propranolol, Topiramate, Inderal, Sotalol, Xanax XR, Benign Essential Tremor, Primidone, Tenormin, Gralise, Horizant, Inderal LA, Betapace, Niravam, Mysoline

Hormonal Treatment of Hot Flashes Still OK for Some: Experts

Posted 18 Oct 2011 by Drugs.com

TUESDAY, Oct. 18 – Women do have options when it comes to treating hot flashes and other symptoms of menopause, and these still include the short-term use of hormone replacement therapy using estrogen alone, experts conclude in a new consensus report. "Hormone replacement therapy should be considered a very reasonable option for recently menopausal women who have moderate-to-severe hot flashes or night sweats," said Dr. JoAnn E. Manson, chief of the division of preventive medicine at Brigham and Women's Hospital in Boston and the current president of the North American Menopause Society (NAMS). Hormone replacement therapy (HRT) was widely used up until 2002. That year, however, the estrogen-plus-progestin arm of the Women's Health Initiative (WHI) trial was stopped early after women who took the formulation were found to have an increased risk for heart disease, strokes, breast cancer ... Read more

Related support groups: Lexapro, Zoloft, Prozac, Gabapentin, Celexa, Paxil, Citalopram, Neurontin, Hot Flashes, Sertraline, Fluoxetine, Escitalopram, Paroxetine, Luvox, Postmenopausal Symptoms, Paxil CR, Fluvoxamine, Gralise, Horizant, Sarafem

Newer Epilepsy Meds Less Likely to Cause Birth Defects: Study

Posted 17 May 2011 by Drugs.com

TUESDAY, May 17 – Newer epilepsy medications don't increase the risk of major birth defects in women taking these drugs during the first trimester of pregnancy, according to new research. But because the drugs are relatively new, further studies are needed to get a clearer picture of their safety profile, experts said. In a large study of children born in Denmark, including those exposed to newer anti-epileptic drugs, researchers found the rate of major birth defects was 3.2 percent for babies born to women taking the epilepsy medications and 2.4 percent for women not taking these drugs. "In a nationwide Danish study of more than 800,000 births, we found no support for an increased risk of birth defects following use of newer generation anti-epileptics in early pregnancy," said the study's lead author, Ditte Molgaard-Nielsen, an epidemiologist at Statens Serum Institute in Copenhagen. ... Read more

Related support groups: Gabapentin, Lamictal, Neurontin, Topamax, Keppra, Lamotrigine, Trileptal, Topiramate, Levetiracetam, Oxcarbazepine, Lamictal XR, Gralise, Horizant, Keppra XR, Lamictal Blue, Topamax Sprinkle, Lamictal Orange, Gabarone, Lamictal ODT, Lamictal CD

Epilepsy Drugs May Raise Fracture Risk in Older Adults

Posted 11 Jan 2011 by Drugs.com

TUESDAY, Jan. 11 – Epilepsy drugs increase older adults' risk for bone fractures, a new study shows. Canadian researchers analyzed the medical records of 15,792 people 50 and older who'd had non-traumatic fractures between April 1996 and March 2004. Each person was matched with up to three people who'd never had a fracture, for a total of 47,289 people to serve as controls. The researchers also looked at the participants' use of epilepsy drugs, including carbamazepine (Carbatrol, Epitol, Tegretol), clonazepam (Klonopin), ethosuximide (Zarontin), gabapentin (Gabarone, Neurontin), phenobarbital (Luminal), phenytoin (Dilantin, Phenytek) and valproic acid (Depakene, Depakote). All but one of the drugs was associated with an increased risk for fractures. The greatest risk was among people taking phenytoin and carbamazepine. Valproic acid was the only drug not linked with an increased chance ... Read more

Related support groups: Klonopin, Gabapentin, Clonazepam, Neurontin, Tegretol, Dilantin, Carbamazepine, Phenobarbital, Phenytoin, Tegretol XR, Valproic Acid, Epitol, Carbatrol, Klonopin Wafer, Zarontin, Depakene, Di-Phen, Equetro, Ethosuximide, Phenytoin Sodium

Epilepsy Drugs Don't Raise Suicide Risk, Study Shows

Posted 5 Aug 2010 by Drugs.com

WEDNESDAY, Aug. 4 – In 2008, the U.S. Food and Drug Administration required epilepsy medications to bear a warning label about an increased risk of suicidal behaviors. The move came after an agency review of 199 studies that found patients taking the drugs showed about twice the risk of suicidal behavior. But now a study of more than 5 million patients contradicts the FDA's findings. It suggests that the increased risk of suicide has more to do with the conditions for which these drugs are prescribed than the medications themselves. For the study, researchers in Spain and the United States evaluated the health records of primary care patients in England. They found that people with epilepsy who currently use an antiepileptic drug are at no greater risk of suicide-related events than those who aren't taking the medications. "In our opinion, in the long term, it is not the drugs ... Read more

Related support groups: Gabapentin, Lyrica, Lamictal, Neurontin, Topamax, Depakote, Keppra, Tegretol, Lamotrigine, Trileptal, Topiramate, Carbamazepine, Pregabalin, Depakote ER, Levetiracetam, Oxcarbazepine, Divalproex Sodium, Zonisamide, Tegretol XR, Zonegran

Drug Combo May Offer Best Relief for Nerve Pain

Posted 16 Jul 2010 by Drugs.com

TUESDAY, Sept. 29 – People with nerve pain respond better to a combination treatment using the anticonvulsant gabapentin and antidepressant nortriptyline than to treatment with either drug alone, according to Canadian researchers. The study findings suggest that combination treatment could be used to help people who only partially respond to one drug or the other. Nerve, or neuropathic, pain – which affects 2 to 3 percent of the population – is "initiated or caused by a primary lesion or dysfunction in the nervous system," according to a news release from The Lancet, which is publishing the study online Sept. 29. Conditions that cause neuropathic pain include nerve problems in the spine, diabetes-related nerve damage and postherpetic neuralgia (PHN), which is nerve pain caused by the varicella zoster virus that can follow an outbreak of shingles. The study included 56 people with PHN ... Read more

Related support groups: Gabapentin, Neurontin, Neuralgia, Nortriptyline, Diabetic Neuropathy, Persisting Pain, Shingles, Diabetic Nerve Damage, Postherpetic Neuralgia, Pamelor, Gabarone, Aventyl HCl

Trial Data on Anti-Seizure Drug Might Have Been Manipulated: Report

Posted 1 Dec 2009 by Drugs.com

WEDNESDAY, Nov. 11 – An unusual look at internal documents from a pharmaceutical company suggests that clinical data was manipulated to make a popular anti-seizure drug, gabapentin (Neurontin), look more effective than it actually was, thereby increasing possibilities for its off-label usage, according to a new report. "This means we're not seeing the full picture, and the picture we are seeing is suspect because perhaps there was selective reporting of outcomes so that only the positive outcomes were reported," said Kay Dickersin, senior author of a paper reporting the alleged deception in the Nov. 12 issue of the New England Journal of Medicine. But this revelation may just be the tip of the iceberg, especially given that internal company research protocols are rarely available to outsiders, stated another expert. "The reality is that a deliberate fraud is extremely difficult to ... Read more

Related support groups: Gabapentin, Neurontin, Gabarone

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Persisting Pain, Shingles, Postherpetic Neuralgia, Epilepsy

Neurontin Patient Information at Drugs.com