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Experimental Drug Fights Bone Marrow Cancers
Posted 3+ months ago by Drugs.com
TUESDAY, Dec. 9 – An experimental drug called CYT387 blocks an enzyme that causes bone marrow cancers called myeloproliferative disorders (MPDs), according to U.S. researchers who conducted tests in mice and human cells.
The findings were to be presented Tuesday at the annual meeting of the American Society of Hematology, in San Francisco.
The researchers, from Oregon Health & Science University's Knight Cancer Institute, found that CYT387 was "very effective" against a specific type of cancer cell driven by an enzyme mutation called JAK2-V617F. The drug binds to the V617F mutation in the JAK2 enzyme. Read more...
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