Melanoma - Metastatic Blog

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Gold Nanospheres Show Promise in 'Boiling' Out Cancer

Posted 3+ months ago by Drugs.com

MONDAY, March 23 – Researchers say that using microscopic gold particles that target melanoma cells and then "boil" them when exposed to certain lighting holds promise as a new treatment for the deadly skin cancer.

The treatment uses gold nanospheres guided directly to the melanoma cells by a special protein fragment called a peptide placed inside the nanosphere. Using a technique known as photoablation therapy (PAT), doctors expose the tumors to near infrared light, causing the nanospheres to heat up and destroy the cancer while leaving healthy tissue alone. Read more...

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Stress May Speed Melanoma Progression

Posted 3+ months ago by Drugs.com

THURSDAY, Feb. 19 – Stress appears to hasten the progression of aggressive or advanced melanoma skin cancer, but commonly prescribed blood pressure drugs may slow the disease and improve the quality of patients' lives, according to an Ohio State University study.

In laboratory tests, the researchers exposed samples of three melanoma cell lines to the stress hormone norepinephrine and looked for changes in the levels of certain proteins released by the cells: vascular endothelial growth factor (VEGF), which stimulates the growth of new blood vessels to feed a growing tumor; and interleukin-6 (IL-6) and interleukin-8 (IL-8), which play a role in tumor growth. Read more...

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