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Older Travelers at Much Higher Risk of Dying From Malaria
Posted 28 Mar 2012 by Drugs.com

WEDNESDAY, March 28 – Tourists over age 65 who visit malaria-infested regions are nearly 10 times more likely to die from the disease than those ages 18 to 35, a new study says. The analysis of 20 years of data from more than 25,000 U.K. patients also found that the malaria death rate is particularly high among people who've traveled to Gambia, West Africa. The risk of dying from malaria, an infection carried by mosquitoes, increased with age, and the death rate for those over age 65 was 4.6 percent. There were no deaths in children younger than age 5, according to the study published online March 28 in the British Medical Journal. The researchers also found that tourists were more than nine times more likely to die from malaria than people of African heritage who traveled to see family or friends – 3 percent vs. 0.32 percent. This decreased death risk among people of African heritage ... Read more
Related support groups: Malaria, Malaria Prevention, Malaria Prophylaxis
Malaria's Global Death Toll Much Higher Than Thought
Posted 3 Feb 2012 by Drugs.com

FRIDAY, Feb. 3 – Malaria killed 1.2 million people worldwide in 2010, a figure nearly double other estimates, a new study says. The researchers also said that although most malaria deaths occur in very young children, 42 percent of deaths occurred in children over age 5 and adults. The findings are published in the Feb. 4 edition of The Lancet. According to the analysis of data collected from 1980 to 2010, global malaria deaths rose from 1 million in 1980 to a peak of 1.8 million in 2004. Since then, increased malaria intervention efforts have helped to reduce malaria death rates, Christopher Murray, of the Institute for Health Metrics and Evaluation at the University of Washington in Seattle, and colleagues noted in journal news release. The 1.2 million malaria deaths in 2010 was a 32 percent decrease from the number of malaria deaths in 2004, the authors noted. In 2010, there were ... Read more
Related support groups: Malaria, Malaria Prevention, Malaria Prophylaxis
Promising Malaria Vaccine May Save Children's Lives
Posted 18 Oct 2011 by Drugs.com

TUESDAY, Oct. 18 – In an important first, a new vaccine has been shown to cut the risk of malaria in young African children by about half, according to research announced Tuesday. Although the effectiveness shown in this Phase 3 trial is far less than the near-100 percent effectiveness often seen in childhood vaccines for other illnesses in the West, the findings are promising, given that malaria kills some 800,000 people in sub-Saharan Africa alone each year. "This potentially translates into [the prevention of] tens of millions of cases of malaria in children," said Dr. Tsiri Agbenyega, a principal investigator of the trial. Other experts agreed. "This is really important because it's a viable strategy against a major killer of children in the world," added Dr. Kenneth Bromberg, chairman of pediatrics and director of the Vaccine Research Center at the Brooklyn Hospital Center, New ... Read more
Related support groups: Malaria, Malaria Prevention, Malaria Prophylaxis
Herbal Derivative Wins Praise as Malaria Treatment
Posted 16 Mar 2011 by Drugs.com

WEDNESDAY, March 16 – Artesunate should replace quinine as the drug of choice for treating malaria, according to an updated review of clinical trial results. Derived from herbs used in Chinese medicine, artesunate was found to be more effective at preventing death in people with severe malaria. The review, published in the Cochrane Library, includes the findings of a large study of African children published last year in The Lancet and eight other clinical trials, all together involving 1,664 adults and 5,765 children from a number of areas in Africa and Asia. The updated review shows that using artesunate to treat people with severe malaria reduces the risk for death by 39 percent in adults and 24 percent in children, compared with quinine. In adults, deaths fell from 241 per 1,000 with quinine to 147 with artesunate. In children, deaths were reduced from 108 per 1,000 with quinine to ... Read more
Related support groups: Malaria, Malaria Prevention, Malaria Prophylaxis
Malaria Vaccine Effective in Latest Trials
Posted 8 Dec 2008 by Drugs.com

MONDAY, Dec. 8 Results from two phase II trials in Africa show that a new malaria vaccine is effective at preventing both infection and the mosquito-borne disease itself in infants and children. "Malaria is killing almost 1 million people, mostly African children, every year," Dr. Christian Loucq, director of the PATH Malaria Vaccine Initiative, said during a morning teleconference Monday. "Clearly, the world needs a safe and effective malaria vaccine." The vaccine, called RTS,S, is one of several vaccine candidates for malaria, Loucq said. Other vaccines are under development, but RTS,S is the one that is furthest along and ready for phase III testing, he noted. "These studies offer further evidence that RTS,S provides both infants and young children with substantial protection against the disease," Loucq said. "We are closer than ever before to having a malaria vaccine for use by the ... Read more
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