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Drugs Can Sometimes Prevent Migraines, but at a Cost

Posted 19 days ago by Drugs.com

MONDAY, April 29 – People with severe or frequent migraines often turn to drugs to prevent them. But do the medications work? A new review of preventive treatments shows there is not much difference in the effectiveness of commonly prescribed drugs – they work for some people, in some cases. But there is wide variation in the amount and severity of side effects associated with the drugs. The researchers found that drugs worked better than inactive placebos in reducing monthly migraine attacks. They prevented half or more migraines in 200 to 400 people per 1,000 treated. But many of the medications had side effects so bothersome that sufferers frequently stopped taking them. That could be because none of the drugs used to prevent migraines was designed specifically for that purpose, explained Dr. Jason Rosenberg, director of the Johns Hopkins Headache Center. "So, it's not surprising ... Read more

Consider Weight When Choosing Blood Pressure Meds: Study

Posted 6 Dec 2012 by Drugs.com

THURSDAY, Dec. 6 – Taking a patient's weight into account when choosing blood pressure medications might help prevent strokes, heart attacks and death, a new study suggests. Lean and obese people react differently to different blood pressure medications, said the researchers, who believe their findings could change the way high blood pressure (hypertension) is treated. "Unexpectedly, people who have high blood pressure and are fat actually have a better prognosis than people who have high blood pressure and are thin," said lead researcher Dr. Michael Weber, a professor of medicine at Downstate Medical Center of the State University of New York in New York City. "You can now choose blood pressure medication as a means of compensating for this difference between obese and thin people, so that it's possible to treat everybody with a medicine that maximizes the outcome regardless of how ... Read more

Heart Failure Drugs Put to the Test

Posted 27 Nov 2012 by Drugs.com

TUESDAY, Nov. 27 – Two new studies examine the effectiveness of medications frequently prescribed for heart failure – the heart's inability to pump blood properly throughout the body. For the 5.7 million Americans who suffer from heart failure, shortness of breath and edema (excessive water retention) can hinder normal activities. Advances in medication have dramatically changed the lives of some patients, but the question facing cardiologists is: What drugs should they prescribe for this difficult-to-treat condition? "Treatment can be difficult because of low blood pressure or kidney disease," said study lead author Dr. Adrian Hernandez. "Other conditions such as depression make it harder for patients to adhere to their medications." And patients with heart failure "are at high risk for mortality or hospitalization for worsening heart failure," he explained. (About 55,000 die of ... Read more

Fainting Spells Often Tied to Too Many Meds at Once: Study

Posted 4 Nov 2012 by Drugs.com

SUNDAY, Nov. 4 – Taking too many medications at the same time could lead to repeated fainting episodes, a new study reveals. "Simply stated, the more antihypertensive pills a patient takes, the greater the likelihood of a possible fainting spell under certain circumstances," explained one cardiologist, Dr. David Friedman, chief of Heart Failure Services at North Shore-LIJ's Plainview Hospital in Plainview, N.Y. He was not involved in the new research. In the study, Danish researchers led by Dr. Martin Ruwald of Copenhagen University Hospital Gentofte looked at more than 127,000 patients, median age 64, who were hospitalized for fainting between 1997 and 2009. Of those patients, more than one-fifth had experienced at least two fainting episodes. The researchers found that the risk of repeat fainting rose with the number of medications that patients were taking at the same time. For ... Read more

More Pregnant Women on Blood Pressure Drugs: Study

Posted 11 Sep 2012 by Drugs.com

TUESDAY, Sept. 11 – Growing numbers of pregnant women are on medicines to treat high blood pressure, new research indicates. "The reasons for the increase are not entirely clear," said study author Dr. Brian Bateman, an assistant professor of anesthesia at Harvard Medical School. While it's important to manage high blood pressure during pregnancy, certain drugs are preferred due to their safety profile. In the study, Bateman found that many women were not on those drugs. "We need to do more research to figure out which medicines are the best for insuring a good pregnancy outcome for both mother and baby," he said. The findings are published in the October issue of Hypertension. Bateman and his colleagues examined Medicaid claims from 2000 to 2007, looking for the records of women who had completed pregnancies. Of the more than 1 million women, nearly 48,500 (4.4 percent) took blood ... Read more

Blood Pressure Drugs Linked to Lip Cancer in Study

Posted 7 Aug 2012 by Drugs.com

MONDAY, Aug. 6 – A new study suggests several high blood pressure drugs, including Adalat, Nifediac and Cordipin, increase the risk of lip cancer in white people, possibly because the medications increase susceptibility to sun damage. Lip cancer is very rare even among those who take the drugs, however, and the preliminary findings shouldn't convince patients to stop taking them, a researcher cautioned. "They should be on the medication that's best for them," said study lead author Dr. Gary Friedman, an adjunct investigator with the Kaiser Permanente Medical Care Program of Northern California in Oakland. "It's really important to emphasize that this is a low-risk condition – a rare cancer that's generally easily treated and not life-threatening." Also, protection from the sun – such as sunscreen and hats – can ward off the sun damage that can lead to lip cancer, Friedman said. ... Read more

U.S. Task Force Issues Blood Pressure Guidelines

Posted 15 May 2012 by Drugs.com

TUESDAY, May 15 – "Team-based care" should be used to improve patients' blood pressure control, the U.S. Task Force on Community Preventive Services recommended on Tuesday. The recommendation is based on a review of 77 studies that showed improvements in patients' control of blood pressure when they received care from a team of health professionals – a primary care doctor supported by a pharmacist, nurse, dietitian, social worker, or community health worker – rather than a primary care doctor alone. The task force found that team-based care increased the percentage of patients with controlled blood pressure, led to a decrease in both systolic (top number) and diastolic (bottom number) blood pressure, and improved results in patients with diabetes and elevated levels of blood fats. Team members assist primary care doctors by providing support and sharing responsibility for high blood ... Read more

New Guidelines Issued for Severe Lupus

Posted 3 May 2012 by Drugs.com

THURSDAY, May 3 – When diagnosed with lupus, one in three people already has kidney inflammation, and during the first 10 years with the disease as many as 60 percent of patients will have some kidney problems. Because kidney inflammation (also called lupus nephritis) is so common in people with lupus, the American College of Rheumatology has issued new guidelines for the screening and management of this potentially devastating complication of lupus. "Without treatment, lupus nephritis can lead to end-stage-renal disease, which requires dialysis or a kidney transplant. But, not all types are this serious. It depends on the pattern of damage to the kidneys," said the lead author of the new guidelines, Dr. Bevra Hahn, a professor of medicine and chief of rheumatology at the David Geffen School of Medicine at the University of California, Los Angeles. Hahn said the course of lupus ... Read more

Treatment Advances Improve the Odds for Heart Failure Patients

Posted 16 Feb 2012 by Drugs.com

THURSDAY, Feb. 16 – Although a growing number of Americans now struggle with heart failure, experts say new treatments have dramatically improved both quality of life and life expectancy for these patients. "The present environment for heart failure is substantially improved, and the future holds promises that will truly remove the term 'failure' from the description of this illness," said Dr. Gregg Fonarow, director of the Ahmanson-UCLA Cardiomyopathy Center in Los Angeles and co-director of the Preventive Cardiology Program at UCLA's David Geffen School of Medicine. Dr. Clyde Yancy, past president of the American Heart Association and chief of cardiology at Northwestern Memorial Hospital in Chicago, seconded that notion, pointing to what he sees as "the edge of a new dawn" in which advances in treatment will enable clinicians to "take the heft, the drama and the 'failure' out of ... Read more

Treating Prehypertension Lowers Stroke Risk: Study

Posted 8 Dec 2011 by Drugs.com

THURSDAY, Dec. 8 – A new study found that the risk of stroke dropped about 22 percent in people with prehypertension who took drugs that lower blood pressure. These people didn't yet have high blood pressure, but they still benefited from taking the medications, although there was no significant reduction in the rate of heart attacks for people taking antihypertensives. "We know that blood pressure and stroke are closely related, and high blood pressure is an extremely high risk factor for stroke. If we could reduce blood pressure, we thought we could reduce the risk of stroke," said lead researcher Dr. Ilke Sipahi, an assistant professor of medicine at Case Western Reserve University's Harrington-McLaughlin Heart and Vascular Institute and University Hospitals Case Medical Center in Cleveland. "We found a highly statistically significant 22 percent risk reduction in stroke with any ... Read more

Taking Blood Pressure Meds at Bedtime May Be Better

Posted 24 Oct 2011 by Drugs.com

MONDAY, Oct. 24 – For the millions of Americans on blood pressure-lowering drugs, a new study suggests that taking the pills at bedtime may be best. It was known that taking blood pressure medications at different times of the day can affect patients' blood pressure patterns, but the impact on health wasn't known. The new Spanish study included 661 patients with chronic kidney disease and hypertension. Half of them took their prescribed blood pressure-lowering drugs at bedtime and half took their medications first thing in the morning. After an average follow-up of 5.4 years, the researchers found that patients who took at least one blood pressure-lowering drug at bedtime had better control of their blood pressure and were about one-third as likely to suffer a heart-related event such as heart attack, heart failure or stroke. The team at the University of Vigo also found that ... Read more

Hypertension, Not Blood Pressure Drugs, Linked to Birth Defects

Posted 19 Oct 2011 by Drugs.com

WEDNESDAY, Oct. 19 – Although pregnant women who have high blood pressure face a higher risk that their baby will be born with birth defects, new research indicates that the medications typically used to treat the condition will not raise that risk any further. The finding suggests that the widely used class of high blood pressure medications known as angiotensin-converting enzyme (ACE) inhibitors are safe to use during the first trimester. Published online Oct. 18 in the BMJ, the study results fill in a piece of the puzzle regarding the use of such medications, given that prior research had indicated that ACE inhibitors can be toxic to a fetus if used in the second and/or third trimester of pregnancy. "Our finding suggests that it is likely the underlying hypertension, rather than use of antihypertensive drugs in the first trimester, that increases the risk of birth defects in ... Read more

Health Tip: Why Cough?

Posted 18 Oct 2011 by Drugs.com

-- Coughing is the body's way of ridding the respiratory tract of an irritating substance. Allergies, asthma or inhaling secondhand smoke are common triggers for a cough. The National Heart Lung and Blood Institute mentions these additional potential causes: Air pollution or inhaling fumes from paint or perfume. Medical conditions such as chronic obstructive pulmonary disease (COPD), heart failure or gastroesophageal reflux disease (GERD). Bronchitis or a respiratory infection. Certain medications, including beta blockers and ACE inhibitors, both commonly prescribed to treat high blood pressure and other cardiovascular problems. Read more

Heart Failure Care Influenced by Insurance Coverage

Posted 19 Sep 2011 by Drugs.com

MONDAY, Sept. 19 – The quality of care people with heart failure receive, along with outcomes, are significantly influenced by what type of insurance patients have, a new study finds. Medicare and Medicaid patients and those without health insurance are less likely to be given some essential treatments and tend to be hospitalized longer, researchers report. Medicaid patients were 22 percent more likely to die in the hospital than patients with private insurance, the researchers said. "I wish the results revealed a different story," said lead researcher Dr. John R. Kapoor, an assistant professor of medicine at the University of Chicago Pritzker School of Medicine. The findings reveal that disparities in heart failure care do exist and are associated with worse outcomes, he added, and these unequal practices should be corrected. "It remains medicine's major unhealed wound that care ... Read more

Accidental Medication Poisonings in Kids on the Rise

Posted 16 Sep 2011 by Drugs.com

FRIDAY, Sept. 16 – Despite ongoing prevention efforts, a growing number of young children are being accidentally poisoned with medications, according to new research. The study, which was based on data reported to the American Association of Poison Control Centers between 2001 and 2008, found that medication poisoning among children aged 5 and under increased by 22 percent, although the number of children in the United States in this age group rose by only 8 percent during the study period. "The problem of pediatric poisoning in the U.S. is getting worse, not better," Dr. Randall Bond, of Cincinnati Children's Hospital Medical Center, said in a hospital news release. In conducting the study, which is scheduled for publication in the Journal of Pediatrics, the researchers reviewed information on over 544,000 children who landed in the emergency department due to medication poisoning ... Read more

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