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Related terms: Cancer, Leukemia

Radon in the Home May Be Linked to Blood Cancers in Women

Posted 7 hours ago by Drugs.com

TUESDAY, May 3, 2016 – New research suggests a strong link between exposure to high levels of radon in the home and women's risk of blood cancers. Radon is a naturally occurring radioactive gas, the U.S. Environmental Protection Agency says. It's known to cause lung cancer and is the second leading cause of lung cancer in the United States, the researchers said. The American Cancer Society collected information over 19 years on more than 140,000 Americans as part of a prevention study. During that time, just over 3,000 cases of blood cancer were diagnosed. The cancers included leukemia, lymphoma and myeloma, the study found. Women who lived in counties with the highest radon levels were 63 percent more likely to develop blood cancers than those in counties with the lowest radon levels. There was no link seen among men, the study noted. The study was published online recently in the ... Read more

Related support groups: Cancer, Leukemia, Lung Cancer, Lymphoma, Non-Small Cell Lung Cancer, Multiple Myeloma, Poisoning, Small Cell Lung Cancer, Toxic Reactions Incl Drug and Substance Abuse

FDA Approves Venclexta (venetoclax) for Chronic Lymphocytic Leukemia with 17p Deletion

Posted 12 Apr 2016 by Drugs.com

April 11, 2016 – The U.S. Food and Drug Administration today approved Venclexta (venetoclax) for the treatment of patients with chronic lymphocytic leukemia (CLL) who have a chromosomal abnormality called 17p deletion and who have been treated with at least one prior therapy. Venclexta is the first FDA-approved treatment that targets the B-cell lymphoma 2 (BCL-2) protein, which supports cancer cell growth and is overexpressed in many patients with CLL. According to the National Cancer Institute, CLL is one of the most common types of leukemia in adults, with approximately 15,000 new cases diagnosed each year. CLL is characterized by the progressive accumulation of abnormal lymphocytes, a type of white blood cell. Patients with CLL who have a 17p deletion lack a portion of the chromosome that acts to suppress cancer growth. This chromosomal abnormality occurs in approximately 10 ... Read more

Related support groups: Leukemia, Chronic Lymphocytic Leukemia (CLL), Venclexta, Venetoclax

Male Childhood Cancer Survivors Less Likely to Have Kids, Study Finds

Posted 24 Feb 2016 by Drugs.com

WEDNESDAY, Feb. 24, 2016 – Men who survived cancer when they were children, teens or young adults seem to be less likely to have children of their own than men who never had cancer, a new study reveals. The likelihood of having children was especially low among those who survived testicular cancer, bone cancer, brain tumors, lymphoma and leukemia, researchers at the University of Bergen in Norway found. The findings "are important for male cancer survivors, seeing as we can identify groups at risk of having reproduction problems," study author Maria Winther Gunnes, a Ph.D. candidate in the department of global public health and primary care, said in a university news release. For the study, researchers reviewed data from all Norwegian men born between 1965 and 1985. Male cancer survivors were three times more likely to use assisted fertilization than those who never had cancer, the ... Read more

Related support groups: Cancer, Female Infertility, Leukemia, Lymphoma, Brain Tumor, Oligospermia, Testicular Cancer

New Immune Therapy Achieves Complete Remission in Blood Cancer Patients

Posted 16 Feb 2016 by Drugs.com

A new therapy that uses a person's immune system to attack tumors led to complete remission in terminally ill blood cancer patients, according to researchers. In a clinical trial, symptoms vanished in 94 percent of leukemia patients who received the treatment. The response rate was more than 80 percent in patients with other blood cancers, and half achieved total remission, CNBC reported. The results were presented Monday at the annual meeting of the American Association for the Advancement of Science. Detailed data will be published later this year. They therapy involves removing immune system T-cells from patients, loading them with anti-cancer molecules, and placing them back in the body. The altered T-cells then seek and destroy cancer, CNBC reported. The results are unprecedented, according to researcher Stanley Riddell. "In the laboratory and in clinical trials, we are seeing ... Read more

Related support groups: Blood Disorders, Cancer, Hairy Cell Leukemia, Leukemia, Chronic Myelogenous Leukemia (CML), Chronic Lymphocytic Leukemia (CLL), Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Diagnosis and Investigation, Acute Lymphocytic Leukemia, Chronic Eosinophilic Leukemia, Acute Nonlymphocytic Leukemia, Acute Promyelocytic Leukemia, Infection Prophylaxis, Chronic Lymphocytic Leukemia, Meningeal Leukemia, Acute Myeloblastic Leukemia

Could IVF Raise Children's Odds for Blood Cancer?

Posted 4 Feb 2016 by Drugs.com

THURSDAY, Feb. 4, 2016 – Children conceived through in vitro fertilization (IVF) might have a slightly increased risk of developing blood cancer, a new study suggests. Children born via IVF had a 67 percent increased risk of leukemia and a more than tripled risk of Hodgkin's lymphoma compared to children conceived naturally, researchers found in an analysis of more than 1.6 million children in Norway. Parents shouldn't panic, however. The risk of childhood cancer is still very small, even after factoring in the results of this study, said lead author Dr. Marte Myhre Reigstad. She is a researcher with the Norwegian National Advisory Unit on Women's Health at Oslo University Hospital. "For example, in Norway, the risk of being diagnosed with leukemia within the first 10 years of life is 0.5 in 1,000," Reigstad said. "A risk increase of such magnitude as found in our study would amount to ... Read more

Related support groups: Female Infertility, Leukemia, Lymphoma, Ovulation Induction, Primary Ovarian Failure, Follicle Stimulation

Genmab Announces U.S. FDA Approval of Arzerra (ofatumumab) as Extended Treatment for Recurrent or Progressive CLL

Posted 20 Jan 2016 by Drugs.com

Copenhagen, Denmark; January 19, 2016 — Genmab A/S (Nasdaq Copenhagen: GEN) announced today that the U.S. Food and Drug Administration (FDA) has approved a supplemental Biologics License Application (sBLA) for the use of Arzerra (ofatumumab) for extended treatment of patients who are in complete or partial response after at least two lines of therapy for recurrent or progressive chronic lymphocytic leukemia (CLL). The application was submitted by Novartis under the ofatumumab collaboration between the two companies. This FDA approval is based on data from an interim analysis from a Phase III study, PROLONG (OMB112517) which evaluated ofatumumab maintenance therapy versus no further treatment in patients with a complete or partial response after second or third line treatment for CLL. "The approval of Arzerra in the U.S. as extended treatment provides patients with relapsed CLL with a ... Read more

Related support groups: Leukemia, Chronic Lymphocytic Leukemia (CLL), Arzerra, Ofatumumab

Antibody May Lower Rejection Rates After Stem Cell Transplant in Leukemia Patients

Posted 7 Jan 2016 by Drugs.com

WEDNESDAY, Jan. 6, 2016 – People with acute leukemia who were given antibody therapy before a stem cell transplant fared better than those who didn't receive the treatment, a small study found. Stem cell transplantation allows doctors to give higher doses of cancer-killing chemotherapy, according to the American Cancer Society. However, the odds of the body rejecting the transplanted stem cells are very high – a condition called graft-versus-host disease, the study authors explained. By treating patients first with animal-derived antibodies, called antihuman T-lymphocyte immune globulin (ATG), the researchers were able to lower the threat of rejection in patients. "Graft-versus-host disease is the most serious complication after stem cell transplantation," said lead researcher Dr. Francesca Bonifazi, from the Institute of Hematology at Bologna University in Italy. "Using [ATG] reduces ... Read more

Related support groups: Hairy Cell Leukemia, Leukemia, Chronic Myelogenous Leukemia (CML), Chronic Lymphocytic Leukemia (CLL), Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Acute Lymphocytic Leukemia, Chronic Eosinophilic Leukemia, Acute Nonlymphocytic Leukemia, Infection Prophylaxis, Chronic Lymphocytic Leukemia, Acute Promyelocytic Leukemia, Acute Myeloblastic Leukemia, Meningeal Leukemia

End-of-Life Talk Often Comes Too Late for Blood Cancer Patients

Posted 21 Dec 2015 by Drugs.com

MONDAY, Dec. 21, 2015 – Many doctors wait too long to have end-of-life discussions with blood cancer patients, a new study finds. Researchers analyzed surveys completed by 349 blood cancer specialists, and found that 56 percent said end-of-life discussions with patients happen too late. Nearly 43 percent said they had their first end-of-life discussions with patients at less-than-ideal times, the findings showed. About 23 percent of the doctors said they waited until death was imminent before discussing hospice care. And nearly 40 percent waited until death was imminent before they asked patients where they wanted to die. Several factors may contribute to the delay in end-of-life discussions with blood cancer patients, according to Dr. Oreofe Odejide, from the Dana-Farber Cancer Institute in Boston, and colleagues. While solid tumors are incurable after they reach an advanced stage, ... Read more

Related support groups: Cancer, Hairy Cell Leukemia, Leukemia, Chronic Myelogenous Leukemia (CML), Chronic Lymphocytic Leukemia (CLL), Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Acute Lymphocytic Leukemia, Acute Nonlymphocytic Leukemia, Chronic Eosinophilic Leukemia, Infection Prophylaxis, Chronic Lymphocytic Leukemia, Acute Promyelocytic Leukemia, Acute Myeloblastic Leukemia, Meningeal Leukemia

Researchers Focus on Risk Factors for Leukemia After Breast Cancer Treatment

Posted 7 Dec 2015 by Drugs.com

MONDAY, Dec. 7, 2015 – Researchers say they're zeroing in on factors that may increase the risk of leukemia after breast cancer treatment. The findings are a step forward in determining ways to prevent this complication in breast cancer survivors. While the breast cancer treatments target malignant cells, they can also affect healthy cells and could increase the risk of leukemia later, the researchers said. The scientists looked at 88 breast cancer survivors with treatment-related leukemia and found that many had a personal and family history of cancer, suggesting a genetic susceptibility to cancer. Also, 20 percent of the women had an inherited gene mutation that increases the risk of breast cancer, according to the study published Dec. 7 in the journal Cancer. "The findings justify a long-term, follow-up study of women with and without inherited breast cancer gene mutations who are ... Read more

Related support groups: Provera, Depo-Provera, Breast Cancer, Lupron, Tamoxifen, Medroxyprogesterone, Arimidex, Leukemia, Femara, Lupron Depot, Anastrozole, Breast Cancer, Metastatic, Zoladex, Evista, Megestrol, Megace, Letrozole, Aromasin, Herceptin, Casodex

Childhood Cancer Tied to Raised Risk for Other Ills in Adult Life

Posted 11 Nov 2015 by Drugs.com

WEDNESDAY, Nov. 11, 2015 – Childhood cancer survivors are at increased risk for diabetes and other autoimmune diseases, a new study suggests. "Cure is no longer a sufficient goal in childhood cancer care," the researchers wrote. "As the vast majority of these patients survive, attention must be paid to their long-term quality of life and health challenges." In the study, the investigators analyzed data from more than 20,000 adults in Denmark, Iceland and Sweden, who had cancer before the age of 20 and survived for at least one year, and compared them to nearly 126,000 adults who did not have childhood cancer. Over an average follow-up of 15 to 19 years, 3.6 percent of childhood cancer survivors were treated in a hospital at least once for an autoimmune disease. That rate is 40 percent higher than among the adults who did not have childhood cancer, according to Dr. Anna Sallfors ... Read more

Related support groups: Diabetes, Type 2, Cancer, Leukemia, Autoimmune Disorders, Brain Tumor, Hodgkin's Lymphoma

Young Cancer Survivors Often Develop New Malignancies

Posted 6 Oct 2015 by Drugs.com

TUESDAY, Oct. 6, 2015 – Teen and young adult cancer survivors are at increased risk for other cancers later in life, a new study reveals. Researchers analyzed U.S. National Cancer Institute data on people who survived cancers before age 40. They had the most common types of cancers in that age group: leukemia, lymphoma, testicular, ovarian, thyroid, breast, soft tissue and bone cancers. "This is a patient demographic that has been largely overlooked," said senior study author Dr. Robert Goldsby, a professor of pediatrics at the University of California, San Francisco Benioff Children's Hospital. Over 30 years, nearly 14 percent of the survivors were diagnosed with another, different type of cancer. On average, the second cancer occurred within 15 years. Compared to people in the general population, patients successfully treated for cancer between ages 15 and 39 were nearly 60 percent ... Read more

Related support groups: Cancer, Breast Cancer, Hairy Cell Leukemia, Leukemia, Chronic Myelogenous Leukemia (CML), Lymphoma, Basal Cell Carcinoma, Melanoma, Skin Cancer, Chronic Lymphocytic Leukemia (CLL), Ovarian Cancer, Non-Hodgkin's Lymphoma, Acute Myeloid Leukemia, Stomach Cancer, Cutaneous T-cell Lymphoma, Hodgkin's Lymphoma, Acute Lymphoblastic Leukemia, Soft Tissue Sarcoma, Acute Lymphocytic Leukemia, Burkitt Lymphoma

Breast-feeding May Lower Risk of Childhood Leukemia: Study

Posted 1 Jun 2015 by Drugs.com

MONDAY, June 1, 2015 – Breast-feeding – even for a short time – may lower a baby's later risk of childhood leukemia, a new study suggests. The researchers found that babies breast-fed for at least six months appear to have a 19 percent lower risk of childhood leukemia compared to children who were never breast-fed or were breast-fed for fewer months. "Breast-feeding is a highly accessible and low-cost preventive public health measure that has been found in numerous studies to be associated not only with lower risk for childhood leukemia but also with lower risk for Sudden Infant Death Syndrome (SIDS), gastrointestinal infection, ear infection, type 2 diabetes and obesity later in life," said the study's lead author, Efrat Amitay, of the School of Public Health at the University of Haifa in Israel. "There is, therefore, a distinct public benefit in breast-feeding and it should be ... Read more

Related support groups: Leukemia, Delivery, Premature Labor, Labor Induction, Lactation Suppression, Cesarean Section, Labor and Delivery including Augmentation

Kids Born to Older Dads May Face Risk of Blood Cancers

Posted 12 May 2015 by Drugs.com

TUESDAY, May 12, 2015 – Adults who were born to older fathers may be at increased risk for blood and immune system cancers such as leukemia and lymphoma, a new study suggests. This association is particularly strong among only children, the American Cancer Society investigators added. However, the study did not prove there was a cause-and-effect link between the two. There was no association between having an older mother and increased risk of these cancers, according to the study published online May 11 in the American Journal of Epidemiology. "The lifetime risk of these cancers is fairly low – about one in 20 men and women will be diagnosed with lymphoma, leukemia or myeloma at some point during their lifetime – so people born to older fathers should not be alarmed," study leader Lauren Teras said in a journal news release. "Still, the study does highlight the need for more ... Read more

Related support groups: Leukemia, Lymphoma, Multiple Myeloma

Contagious Leukemia Killing East Coast Clams

Posted 9 Apr 2015 by Drugs.com

THURSDAY, April 9, 2015 – A lethal marine cancer killing clams along North America's East Coast is contagious, new research indicates. Scientists say they've traced leukemia outbreaks among soft-shell clams from New York to Canada back to one case of cancer, which was transmitted to other clams. "The evidence indicates that the tumor cells themselves are contagious – that the cells can spread from one animal to another in the ocean," said researcher Stephen Goff of the Howard Hughes Medical Institute and Columbia University in New York City. "We know this must be true because the genotypes of the tumor cells do not match those of the host animals that acquire the disease, but instead all derive from a single lineage of tumor cells," Goff explained. The findings, published April 9 in Cell, suggest that cells can survive in seawater long enough to reach and infect a new host. The ... Read more

Related support groups: Leukemia

Gene Mutations Tied to Leukemia Rise With Age, Study Finds

Posted 26 Feb 2015 by Drugs.com

THURSDAY, Feb. 26, 2015 – For many people, an increase in genetic mutations that could trigger leukemia seems to be an inevitable part of aging, a new study finds. The British researchers looked specifically at mutations in blood stem cells. "Over time, the probability of these cells acquiring mutations rises," co-lead author Thomas McKerrell, of the Wellcome Trust Sanger Institute, said in an institute news release. "What surprised us was that we found these mutations in such a large proportion of elderly people," he added. In the study, researchers looked at more than 4,200 people without any evidence of blood cancer. They found that up to 20 percent of people aged 50 to 60, and more than 70 percent of people older than 90, have blood cells with the same gene changes seen in leukemia. Just carrying a particular mutation doesn't mean that a leukemia is guaranteed, however. "Leukemia ... Read more

Related support groups: Blood Disorders, Leukemia

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Chronic Myelogenous Leukemia (CML), Chronic Lymphocytic Leukemia (CLL), Acute Lymphocytic Leukemia, Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Acute Nonlymphocytic Leukemia, Hairy Cell Leukemia, Chronic Eosinophilic Leukemia, Meningeal Leukemia, Acute Myeloblastic Leukemia, Blood Disorders

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