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FDA Medwatch Alert: Statins and HIV or Hepatitis C Drugs: Drug Safety Communication - Interaction Increases Risk of Muscle Injury
Posted 2 Mar 2012 by Drugs.com
ISSUE: FDA notified healthcare professionals of updates to the prescribing information concerning interactions between protease inhibitors and certain statin drugs. Protease inhibitors and statins taken together may raise the blood levels of statins and increase the risk for muscle injury (myopathy). The most serious form of myopathy, called rhabdomyolysis, can damage the kidneys and lead to kidney failure, which can be fatal. BACKGROUND: Statins are a class of prescription drugs used together with diet and exercise to reduce blood levels of low-density lipoprotein (LDL) cholesterol (“bad cholesterol”). HIV protease inhibitors are a class of prescription anti-viral drugs used to treat HIV. HCV protease inhibitors are a class of prescription anti-viral drugs used to treat hepatitis C infection. RECOMMENDATION: Healthcare professionals should follow the recommendations in the pr ... Read more
Related support groups: Simvastatin, Lipitor, Crestor, Pravastatin, Zocor, Lovastatin, Incivek, Atorvastatin, Livalo, Rosuvastatin, Red Yeast Rice, Pravachol, Victrelis, Kaletra, Lescol
Anti-HIV Drugs May Help Prevent Spread of Virus
Posted 27 May 2010 by Drugs.com
THURSDAY, May 27 – People who are HIV-positive can lower their risk for transmitting the virus to their partners by 90 percent by taking antiretroviral drugs, new research has found. Antiretroviral drug therapy helps reduce HIV levels in the infected person's blood, which in turn makes the person less infectious to others. The drugs are commonly taken in the United States by people with HIV, the virus that causes AIDS. In the new research, published online May 26 in The Lancet, investigators studied more than 3,400 heterosexual couples in seven African countries. In each couple, one person was infected with HIV and the other was not. No one in the study was taking antiretroviral drugs. Health workers counseled the couples about preventing HIV transmission and followed up with them for two years. During that time, periodic blood tests measured HIV levels in the blood, and people were ... Read more
Related support groups: HIV Infection, Atripla, Truvada, Baraclude, Kaletra, Norvir, Hepsera, Combivir, Ritonavir, Lexiva, Norvir Soft Gelatin, Viread, Entecavir, Nevirapine, Reyataz
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HIV Infection, Nonoccupational Exposure, Occupational Exposure