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Medicare Spends Billions on Chronic Kidney Disease, Study Finds

Posted 29 Mar 2016 by Drugs.com

TUESDAY, March 29, 2016 – Chronic kidney disease affects nearly 14 percent of Americans and costs Medicare billions of dollars a year, a new study reveals. In 2013, Medicare spent $50 billion on chronic kidney disease among people 65 and older, and $31 billion on those with kidney failure, the researchers found. "This report is a one-stop shop to try to understand the prevalence of kidney disease, how it's being treated and how the burden affects various populations," researcher Rajesh Balkrishnan, a professor of public health sciences at the University of Virginia School of Medicine, said in a university news release. "If we can identify which treatment modalities are working and how they're used and link these treatments to outcomes, we can inform the government of the most cost-effective ways to manage and treat the growing burden of kidney disease in the U.S.," he added. The study ... Read more

Related support groups: Renal Failure, Chronic Kidney Disease, Diabetic Kidney Disease, Peritoneal dialysis, Diabetic Nephropathy, Anemia Associated with Chronic Renal Failure, Renal Osteodystrophy, Renal Artery Atherosclerosis, Renal and Genitourinary Disorders, Hypertensive Renal Disease, Renovascular Hypertension, Anuria, Hyperphosphatemia of Renal Failure, Hypertensive Heart (w/ CHF) and Renal Disease

Paying for Kidneys Might Boost Donor Rate, Study Says

Posted 23 Mar 2016 by Drugs.com

WEDNESDAY, March 23, 2016 – If offered $50,000, nearly three out of five Americans would part with a kidney, a new study finds. "It appears that American society is ready to accept the concept of paying kidney donors," said lead researcher Dr. Thomas Peters, an emeritus professor of surgery at the University of Florida College of Medicine, in Jacksonville. However, Peters isn't suggesting that a paid market for kidneys start anytime soon, only that the idea be studied to see if it might increase the supply of kidneys. Paying for organs is illegal under the U.S. National Organ Transplant Act. When the law was enacted, "the feeling was that altruism should prevail," Peters said. "Organs should not become a commodity, and the giving was as important as receiving. "Laws should be amended or changed, so at least pilot studies regarding this question could be carried out to see if kidney ... Read more

Related support groups: Renal Failure, Chronic Kidney Disease, Organ Transplant - Rejection Prophylaxis, Peritoneal dialysis, Organ Transplant, Renal Osteodystrophy, Hyperphosphatemia of Renal Failure

Kidney Dialysis Might Not Extend Survival of Elderly

Posted 18 Mar 2016 by Drugs.com

THURSDAY, March 17, 2016 – Dialysis does not significantly improve survival for elderly kidney failure patients, a new study indicates. The findings suggest that conservative care may be a reasonable option for some kidney failure patients over 80. The researchers don't say that dialysis treatment should not be given to anybody older than 80 or with severe co-occurring conditions. "But we show that the treatment is on average of little advantage regarding survival," said study co-leader Dr. Wouter Verberne of St. Antonius Hospital in Nieuwegein, the Netherlands. The findings were published online March 17 in the Clinical Journal of the American Society of Nephrology. "Our next task is to predict who benefits and who does not," Verberne said in a journal news release. "Until we are able to give a better prediction of the results of dialysis treatment at high age, we can merely suggest ... Read more

Related support groups: Renal Failure, Chronic Kidney Disease, Diabetic Kidney Disease, Peritoneal dialysis, Hemodialysis, Diabetic Nephropathy, Hyperphosphatemia of Renal Failure, Renal and Genitourinary Disorders

Blacks More Likely to Have Kidney Failure Than Whites: Study

Posted 11 Mar 2016 by Drugs.com

THURSDAY, March 10, 2016 – Black Americans are at greater risk for kidney failure than whites, but this racial difference is not explained by the fact that blacks are more likely to have gene variants associated with kidney disease, a new study shows. The findings suggest that widespread screening for these gene variants in blacks is not yet justified, the researchers said. These variants occur in a gene called apolipoprotein L1 (APOL1), which produces a protein that is part of "good" HDL cholesterol. About 5 million black Americans have APOL1 variants, but not all people with these variants develop kidney disease. The Johns Hopkins researchers analyzed data from more than 15,000 Americans who were followed for nearly 25 years. During that time, black participants had a higher risk of developing high blood pressure, diabetes and kidney failure than whites. But kidney function decline ... Read more

Related support groups: Renal Failure, Chronic Kidney Disease, Peritoneal dialysis, Hyperphosphatemia of Renal Failure

Anemia Drugs May Not Boost Kidney Patients' Well-Being: Study

Posted 16 Feb 2016 by Drugs.com

MONDAY, Feb. 15, 2016 – The pricey anemia drugs often given to people with chronic kidney disease may make no difference in how they feel day to day, a new research review confirms. Researchers said the study results back up current guidelines on how to use the drugs, called erythropoietin-stimulating agents (ESAs). These include the injection drugs marketed under the names Procrit, Epogen and Aranesp. Patients may still benefit from the medications because they reduce the need for blood transfusions to treat severe anemia, said Dr. Navdeep Tangri, senior researcher on the study. "But this should close the book on the idea that these drugs help with exhaustion and improve patients' quality of life," said Tangri, an attending doctor at Seven Oaks General Hospital Renal Program in Manitoba, Canada. However, one expert argued that while on average, that is true, some patients do feel ... Read more

Related support groups: Renal Failure, Anemia, Chronic Kidney Disease, Peritoneal dialysis, Aranesp, Procrit, Epogen, Renal Osteodystrophy, Darbepoetin Alfa, Mircera, Anemia Associated with Chronic Disease, Epoetin Beta-Methoxy Polyethylene Glycol, Epoetin Alfa, Omontys, Peginesatide, Hyperphosphatemia of Renal Failure

Racial Disparity in Kidney Transplant Outcomes Narrows: Study

Posted 5 Feb 2016 by Drugs.com

THURSDAY, Feb. 4, 2016 – Racial disparities in kidney transplant outcomes are shrinking, new research indicates. Previous studies had shown that black patients who received kidney transplants had worse outcomes compared with white patients. But a new analysis of roughly 200,000 kidney transplants revealed that the success of surgeries involving black people improved between 1990 and 2012, with fewer organ rejections and deaths among these patients. The study authors compared information on almost 64,000 black and more than 145,400 white adults who received a kidney from a living or deceased donor. The findings were published online Feb. 4 in the Journal of the American Society of Nephrology. "We hypothesized that advances in immunosuppression and post-transplant management might differentially benefit black kidney transplant recipients, who were disproportionately burdened by ... Read more

Related support groups: Renal Failure, Chronic Kidney Disease, Organ Transplant - Rejection Prophylaxis, Peritoneal dialysis, Organ Transplant, Renal Osteodystrophy, Graft-versus-host disease, Rejection Prophylaxis, Hyperphosphatemia of Renal Failure

New Kidney Transplant Drug Cuts Risk of Earlier Death: Study

Posted 28 Jan 2016 by Drugs.com

WEDNESDAY, Jan. 27, 2016 – A newer drug used for preventing organ rejection might improve the long-term outlook for kidney transplant recipients, a new study finds. Over seven years, patients given the drug belatacept (brand name: Nulojix) were 43 percent less likely to die or see their donor kidney fail compared to patients given an older drug called cyclosporine. Experts said the findings should encourage more doctors and patients to choose belatacept over standard anti-rejection medications. "This is a potentially transformational drug," said study lead researcher Dr. Flavio Vincenti, a transplant specialist at the University of California, San Francisco. The study – funded by the drug's maker, Bristol-Myers Squibb – was published in the Jan. 28 issue of the New England Journal of Medicine. Belatacept was first approved by the U.S. Food and Drug Administration in 2011 for ... Read more

Related support groups: Renal Failure, Kidney Infections, Restasis, Cyclosporine, Chronic Kidney Disease, Organ Transplant - Rejection Prophylaxis, Peritoneal dialysis, Neoral, Organ Transplant, Organ Transplant - Rejection Reversal, Renal Osteodystrophy, Pyelonephritis, Gengraf, Graft-versus-host disease, Rejection Prophylaxis, Sandimmune, Hyperphosphatemia of Renal Failure, Belatacept, Nulojix

Kidney Woes Tied to Raised Cancer Risk, Study Finds

Posted 12 Nov 2015 by Drugs.com

THURSDAY, Nov. 12, 2015 – Kidney failure and having a kidney transplant may increase the risk for certain types of cancer, a new study suggests. Poor kidney function and immune system-suppressing drugs may be behind this increased risk, according to Elizabeth Yanik, of the U.S. National Cancer Institute, and colleagues. For the study, published in the Nov. 12 online edition of the Journal of the American Society of Nephrology, the researchers looked at data from more than 200,000 U.S. kidney transplant candidates and recipients. Along with finding that these patients are at increased risk for certain types of cancer, the investigators also identified clear patterns of risk associated with different types of treatment. However, the associations seen in the study do not prove cause-and-effect. The risk of kidney and thyroid cancers was especially high when kidney failure patients were on ... Read more

Related support groups: Cancer, Methotrexate, Renal Failure, CellCept, Gilenya, Tysabri, Imuran, Chronic Kidney Disease, Orencia, Xolair, Revlimid, Leflunomide, Azathioprine, Arava, Afinitor, Tecfidera, Peritoneal dialysis, Mycophenolate Mofetil, Benlysta, Myfortic

Kidney Patients Without Online Access Face Additional Burden

Posted 22 Oct 2015 by Drugs.com

THURSDAY, Oct. 22, 2015 – Disadvantaged chronic kidney disease patients are less likely to have access to electronic health resources, a new study finds. This problem among blacks, the poor, seniors and Medicaid/Medicare beneficiaries may strengthen or increase existing health-related inequities associated with race and income, the researchers said. They added that being able to go online to check medical information and communicate with health care providers enables patients to learn more about kidney disease and might help them follow their doctor's recommendations. The study will be published in the Clinical Journal of the American Society of Nephrology. "Unfortunately, in the setting of (chronic kidney disease), it appears that black patients and patients of lower socioeconomic status are often left behind when it comes to using these technologies," study author Dr. Khaled ... Read more

Related support groups: Renal Failure, Chronic Kidney Disease, Peritoneal dialysis, Renal Osteodystrophy, Hyperphosphatemia of Renal Failure

A High Salt and Potassium Diet May Accelerate Chronic Kidney Disease

Posted 17 Sep 2015 by Drugs.com

THURSDAY, Sept. 17, 2015 – A diet high in sodium and potassium can make chronic kidney disease (CKD) worse, a new study claims. "These data warrant future clinical trials to test the effect of a moderate reduction in dietary sodium and potassium intake on CKD progression in patients with high dietary sodium or potassium intake," study leader Dr. Jiang He, from Tulane University, said in a news release from the American Society of Nephrology. "The findings could ultimately impact dietary recommendations for patients with CKD to slow disease progression," He added. It's estimated that 26 million people in the United States have chronic kidney disease, the researchers said. Chronic kidney disease can lead to kidney failure and also increases the risk for heart disease and early death, according to the study authors. For the study, the researchers tested urine samples from almost 4,000 ... Read more

Related support groups: Renal Failure, Klor-Con, Potassium Chloride, Chronic Kidney Disease, Sodium Chloride, Peritoneal dialysis, Klor-Con M20, Klor-Con M10, K + Potassium, HalfLytely and Bisacodyl, K-Dur, Klor-Con 10, K-Tab, Hyper-Sal, Rhinaris, K-Dur 20, Micro-K 10, K-10, Slow-K, Micro-K

Kidney Donors, Recipients Want to Know More About Each Other

Posted 18 Aug 2015 by Drugs.com

TUESDAY, Aug. 18, 2015 – Most living kidney donors and recipients would like to know more about each other's health before a transplant, a new study indicates. Currently, a transplant candidate must be told if the donor is at increased risk for hepatitis or HIV, but rules are unclear about what other health information can be shared. "Our finding that both donors and recipients support greater sharing of health and health-behavior information challenges the current approach to disclosure in organ transplantation," said study author Dr. Lainie Friedman Ross, of the University of Chicago. Researchers surveyed 76 kidney transplant recipients or candidates and 160 potential or actual donors. They found that 88 percent of the respondents said recipients should receive donors' general health information, and nearly four out of five said donors should be given recipients' general health ... Read more

Related support groups: Renal Failure, Renal Transplant, Organ Transplant - Rejection Prophylaxis, Peritoneal dialysis, Organ Transplant, Hyperphosphatemia of Renal Failure

Too Few Kidney Dialysis Patients Referred for Organ Transplant, Study Finds

Posted 11 Aug 2015 by Drugs.com

TUESDAY, Aug. 11, 2015 – Although a kidney transplant is considered the best hope for people struggling with end-stage renal disease, a new study conducted in Georgia found three-quarters of these patients weren't even evaluated for a possible transplant within their first year of dialysis. That finding flies in the face of U.S. regulations that require all dialysis centers to fully inform these patients about all available treatment options. Those options include kidney transplantation, a typically less expensive intervention than ongoing dialysis and one that also promises greater longevity and a better quality of life, the researchers noted. What's more, the team found a huge variation in statewide referral rates. Some dialysis centers failed to send even a single first-year patient for a transplant consultation, while others referred 75 percent of their new patients. It remains ... Read more

Related support groups: Renal Failure, Renal Transplant, Chronic Kidney Disease, Diabetic Kidney Disease, Peritoneal dialysis, Diabetic Nephropathy, Organ Transplant, Renal Osteodystrophy, Hyperphosphatemia of Renal Failure, Hypertensive Renal Disease, Anuria, Renal and Genitourinary Disorders

Kidney Problems Linked to Brain Disorders: Study

Posted 6 Aug 2015 by Drugs.com

THURSDAY, Aug. 6, 2015 – Kidney problems can increase the risk of brain disorders, a new study finds. The findings suggest that protecting kidney health may also benefit the brain, the researchers said. They studied data from more than 2,600 people in the Netherlands, and found that poor kidney function was strongly associated with decreased blood flow to the brain. They also saw an increased risk of stroke and memory and thinking problems (dementia) in people with kidney problems. The association was independent of known heart disease risk factors, the researchers said. The study was published Aug. 6 in the Journal of the American Society of Nephrology. "Our findings provide a possible explanation linking kidney disease to brain disease," Dr. M. Arfan Ikram, an assistant professor of neuroepidemiology at Erasmus University Medical Center in the Netherlands, said in a journal news ... Read more

Related support groups: Dementia, Renal Failure, Alzheimer's Disease, Kidney Infections, Chronic Kidney Disease, Mild Cognitive Impairment, Diabetic Kidney Disease, Peritoneal dialysis, Diabetic Nephropathy, Anemia Associated with Chronic Renal Failure, Polycystic Kidney Disease, Renal Osteodystrophy, Pyelonephritis, Hyperphosphatemia of Renal Failure, Renal Vein Thrombosis, Lewy Body Dementia, Renal and Genitourinary Disorders, Renovascular Hypertension

U.S. Dialysis Patients Increasingly Live in Poor Areas

Posted 24 Jun 2015 by Drugs.com

WEDNESDAY, June 24, 2015 – More than one-third of kidney dialysis patients in the United States live in poor neighborhoods, a study finds. Kidney dialysis rates in the United States are higher in poor neighborhoods, and they're increasing in those areas, the 15-year analysis shows. Dialysis is used to treat people with kidney failure. Researchers analyzed U.S. Centers for Medicare and Medicaid Services data to assess overall dialysis rates and those in poor areas, defined as having a a zip code where at least 20 percent of people live below the federal poverty line. The results showed that 27.4 percent of adults who began dialysis between 1995 and 2004 lived in poor neighborhoods, compared with about 11 percent of adults in the general population. Those percentages increased to 34 percent and 12.5 percent, respectively, between 2005 and 2010, said the researchers from Loyola University ... Read more

Related support groups: Renal Failure, Chronic Kidney Disease, Diabetic Kidney Disease, Peritoneal dialysis, Diabetic Nephropathy, Renal Osteodystrophy, Hyperphosphatemia of Renal Failure

Keryx Biopharmaceuticals Announces Trade Name Auryxia for Ferric Citrate

Posted 17 Nov 2014 by Drugs.com

NEW YORK, Nov. 17, 2014 (GLOBE NEWSWIRE) – Keryx Biopharmaceuticals, Inc., a biopharmaceutical company focused on bringing innovative therapies to market for patients with renal disease, today announced that the U.S. Food and Drug Administration (FDA) has approved the trade name Auryxia (ferric citrate) for its FDA-approved ferric citrate. Auryxia, an iron-based phosphate binder, was approved by the FDA to control serum phosphorus levels in patients with chronic kidney disease (CKD) on dialysis in September 2014. Ron Bentsur, Chief Executive Officer of Keryx, commented, "We are excited to receive FDA approval of the trade name Auryxia. We look forward to launching Auryxia in the U.S. at year end and to providing nephrologists with an effective phosphate binder for dialysis-dependent CKD patients." For more information about Auryxia, please visit www.Auryxia.com. About End Stage ... Read more

Related support groups: Ferric Citrate, Hyperphosphatemia of Renal Failure

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