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Related terms: Cancer, Hodgkin's Lymphoma, Hodgkin's Disease, Lymphoma, Hodgkin's
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More Aggressive Chemo May Help Younger Lymphoma Patients: Study
Posted 27 Nov 2011 by Drugs.com
THURSDAY, Nov. 24 – Higher doses of chemotherapy with less time between treatments may benefit younger people suffering from aggressive lymphomas, such as diffuse large B-cell lymphoma (one of the most common and aggressive forms of non-Hodgkin's lymphoma), according to new research. A study published online Nov. 24 in The Lancet found this intensive form of chemotherapy, when combined with the monoclonal antibody drug rituximab, may reduce recurrence of the disease and increase survival rates among patients under 60 years of age. The researchers said these younger patients are about twice as likely to remain in remission after three years versus those given rituximab plus the standard chemotherapy treatment known as CHOP (cyclophosphamide, doxorubicin, vincristine, and prednisone). In conducting the study, researchers led by Dr. Herve Tilly of the University of Rouen in France gave ... Read more
Related support groups: Prednisone, Lymphoma, Rituxan, Rituximab, Cytoxan, Adriamycin, Cyclophosphamide, Vincristine, Hodgkin's Lymphoma, Sterapred DS, Bleomycin, Deltasone, Doxorubicin, Sterapred, Oncovin
Study Finds Big Strides Made in Treating Leukemia, Lymphoma in Past Decade
Posted 24 Nov 2010 by Drugs.com
WEDNESDAY, Nov. 24 – Clinicians have made remarkable advances in treating blood cancers with bone marrow and blood stem cell transplants in recent years, significantly reducing the risk of treatment-related complications and death, a new study shows. Between the early 1990s and 2007, there was a 41 percent drop in the overall risk of death in an analysis of more than 2,500 patients treated at Fred Hutchinson Cancer Center in Seattle, a leader in the field of blood cancers and other malignancies. Researchers from the Fred Hutchinson Cancer Center, who conducted the study, also noted dramatic decreases in treatment complications such as infection and organ damage. The study was published in the Nov. 24 issue of the New England Journal of Medicine "We have made enormous strides in understanding this very complex procedure and have yielded quite spectacular results," said study senior ... Read more
Related support groups: Hairy Cell Leukemia, Leukemia, Chronic Myelogenous Leukemia (CML), Lymphoma, Chronic Lymphocytic Leukemia (CLL), Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Cutaneous T-cell Lymphoma, Non-Hodgkin's Lymphoma, Hodgkin's Lymphoma, Acute Lymphocytic Leukemia, Follicular Lymphoma, Acute Nonlymphocytic Leukemia, Infection Prophylaxis, Chronic Lymphocytic Leukemia, Acute Promyelocytic Leukemia
Less May Be More When Treating Early Hodgkin's
Posted 11 Aug 2010 by Drugs.com
WEDNESDAY, Aug. 11 – Fewer cycles of chemotherapy and lower dosages of radiation may work just as well as more intensive treatment for early-stage Hodgkin's lymphoma, a new study suggests. Researchers in Germany randomly assigned 1,370 patients with early-stage Hodgkin's lymphoma into four groups: four cycles of chemotherapy followed by either 30 Gy of radiation or 20 Gy of radiation; or two cycles of chemo followed by 30 Gy of radiation or 20 Gy of radiation. Gy is the abbreviation for gray, a unit of measurement for radiation. The chemotherapy was a four-drug combination – doxorubicin, bleomycin, vinblastine and dacarbazine (ABVD) – the standard treatment for the disease. After five years, 91.1 percent of patients in the weakest treatment group (two cycles of chemo and the lesser dosage of radiation) had not experienced a relapse, while 93 percent of those in the strongest ... Read more
Related support groups: Hodgkin's Lymphoma
Lymphoma Survivors Often Miss Out on Follow-Up
Posted 19 Jun 2010 by Drugs.com
FRIDAY, June 18 – Many Hodgkin lymphoma survivors don't receive recommended follow-up screening tests for other cancers, a new study finds. "Most [Hodgkin lymphoma] patients are cured, but they can be at risk many years later of developing secondary cancers or other late effects of their initial treatment. This is why quality of follow-up care post-treatment is so important," principal investigator Dr. David Hodgson, a radiation oncologist at the Princess Margaret Hospital Cancer Program in Toronto, Canada, said in a University Health Network news release. He and his colleagues followed 2,071 survivors for up to 15 years after Hodgkin lymphoma diagnosis and found that 62.5 percent were not screened for colorectal cancer, 32.3 percent were not screened for breast cancer, and 19.9 percent were not screened for cervical cancer. "Our results indicate that the optimal follow-up care did not ... Read more
Related support groups: Hodgkin's Lymphoma
Kids Who Beat Cancer Still Face Heart Risks
Posted 9 Dec 2009 by Drugs.com
WEDNESDAY, Dec. 9 – Survivors of childhood cancer have a significantly increased risk for developing heart disease as young adults, a new study finds. The finding came from an analysis of data on 14,358 five-year cancer survivors who were diagnosed before age 21 and 3,899 siblings of cancer survivors. The cancers were leukemia, brain cancer, Hodgkin's lymphoma, non-Hodgkin's lymphoma, kidney cancer, neuroblastoma, soft tissue carcinoma or bone cancer. The study found that young adult survivors of these childhood cancers are much more likely than others in their age group to have cardiovascular problems, including heart failure, heart attack, heart inflammation and heart valve abnormalities, for up to 30 years after being treated for cancer. They also found that the risk was associated with lower exposure to chemotherapy and radiation treatment than previously thought. "Young adults who ... Read more
Related support groups: Hairy Cell Leukemia, Leukemia, Chronic Myelogenous Leukemia (CML), Brain Tumor, Renal Cell Carcinoma, Osteosarcoma, Chronic Lymphocytic Leukemia (CLL), Acute Myeloid Leukemia, Glioblastoma Multiforme, Acute Lymphoblastic Leukemia, Pituitary Tumor, Non-Hodgkin's Lymphoma, Hodgkin's Lymphoma, Acute Lymphocytic Leukemia, Anaplastic Oligodendroglioma
Radiation May Raise Stroke Risk After Hodgkin's
Posted 17 Jun 2009 by Drugs.com
WEDNESDAY, June 17 – Hodgkin's lymphoma survivors who are treated with radiation therapy have a greatly increased risk of stroke and transient ischemic attack, also called a "mini-stroke," new research has found. Flora E. van Leeuwen and colleagues at the Netherlands Cancer Institute in Amsterdam studied 2,201 people with Hodgkin's lymphoma who had been treated before age 51 and had survived at least five years after their diagnosis. After a median follow-up of 18 years, the researchers found that they were 2.2 times more likely to suffer a stroke and 3.1 times more likely to experience a transient ischemic attack (TIA) than people in the general population. Radiation to the head and neck was associated with this increased risk, but not chemotherapy. "For young survivors of Hodgkin's lymphoma, who are at especially increased risk of stroke and TIA, physicians should consider ... Read more
Related support groups: Hodgkin's Lymphoma
DNA Variations May Alter Risk of Hodgkin's Disease
Posted 9 Mar 2009 by Drugs.com
MONDAY, March 9 – The chances of developing Hodgkin's disease could be up to four times greater for people with certain variations in genes that repair DNA, a new study shows. Researchers at the University of Texas M.D. Anderson Cancer Center in Houston found the association based on their analysis of variants in five DNA repair genes (XPC, XPD, XPG, XRCC1, and XRCC3) in 420 people, about half of whom had Hodgkin's disease, a type of lymphoma. Proteins that fix damaged DNA help maintain cell health and help stave off cancer by preventing genetic damage from piling up. Previous studies have linked reduced DNA repair in people to susceptibility to certain cancers, including breast, colon and lung cancer. The latest findings, scheduled to appear in the April 15 issue of Cancer, suggest that more study is needed of these genes and their possible role in the development of Hodgkin's ... Read more
Related support groups: Hodgkin's Lymphoma
Hodgkin's Survivors Prone to Breast Cancer Later
Posted 16 Feb 2009 by Drugs.com
MONDAY, Feb. 16 – In an ironic testament to the success of childhood cancer treatments, researchers report that women who were treated as children with radiation for Hodgkin's disease were almost 40 times more likely to develop breast cancer later in life. "We can cure most patients now who have Hodgkin's disease. Back in 1950, it was regarded as a universally fatal disease," said study co-author Dr. Nancy Mendenhall, a professor of radiation oncology at the University of Florida College of Medicine in Gainesville. "[But] when you've got a high cure rate, as people age, you begin to identify some of the unanticipated effects that seem to be related to the treatments. If you don't cure the patients, they don't survive to see those effects." The risk rose with the radiation dose, and there was also a higher risk of developing malignancies in both breasts. The findings, published in the ... Read more
Related support groups: Hodgkin's Lymphoma
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