Join the 'Graft-versus-host disease' group to help and get support from people like you.

Graft-versus-host disease Blog

Related terms: GVHD

HIV Drug May Prevent Bone Marrow Transplant Complication

Posted 11 Jul 2012 by Drugs.com

WEDNESDAY, July 11 – An HIV drug significantly reduced the risk of graft-versus-host disease, an all-too-common complication in blood cancer patients following bone marrow transplants, new research finds. Bone marrow is the spongy tissue inside the bones that contains immature cells, or stem cells. In an "allogeneic" bone marrow transplantation, also called a stem cell transplant, a patient's own stem cells and immune system are wiped out by chemotherapy and radiation. Then, the patient receives the transplant, or bone marrow, from a closely matched donor. The treatment is used for several types of blood cancers, including lymphoma and leukemia. But a common complication of a bone marrow transplant is graft-versus-host disease. It occurs when transplanted immune cells attack patients' healthy tissue, a complication that can be minor or life-threatening. "Graft-versus-host disease ... Read more

Related support groups: Graft-versus-host disease, Maraviroc, Selzentry

Treatment May Limit Graft-Versus-Host Disease

Posted 12 Jan 2010 by Drugs.com

WEDNESDAY, Aug. 19 – People who need a blood stem-cell transplant may be able to lessen the chances that the transplanted material will attack the body – what's known as graft-versus-host disease – by being treated with anti-T-cell globulin, a new study has shown. Graft-versus-host disease (GVHD) occurs in up to 60 percent of those who have a transplant of blood stem cells – called hematopoietic cell transplantation – from the bone marrow or peripheral blood of unrelated donors. In GVHD, the immune system or T-cells from the donor recognize the recipient's tissues as foreign and attack. Previous research has suggested that antibodies that eliminate T-cells might prevent this attack. The new study included 201 adults with blood cancer who were scheduled for a transplant from an unrelated donor. One group was given standard treatment to prevent GVHD prophylaxis (cyclosporine and ... Read more

Related support groups: Graft-versus-host disease

Ask a Question

Further Information

Related Condition Support Groups

Organ Transplant

Related Drug Support Groups

prednisone, methotrexate, cyclosporine, tacrolimus, mycophenolate mofetil, Deltasone, Sterapred, Liquid Pred, Methotrexate LPF Sodium, view more... Trexall, Sterapred DS, Prednicot, Folex PFS, Meticorten, Orasone, Prednicen-M