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Glaucoma (Open Angle) Blog

Alcon Announces FDA Approval of Simbrinza Suspension, a New Beta Blocker-Free, Fixed-Combination Therapy for Glaucoma Patients

Posted 23 Apr 2013 by Drugs.com

Basel, April 19, 2013 – Alcon, the global leader in eye care and a division of Novartis, announces US FDA approval for Simbrinza Suspension, indicated for the reduction of elevated intraocular pressure (IOP) in patients with primary open-angle glaucoma or ocular hypertension.4 Elevated IOP is the only modifiable risk factor for glaucoma. Glaucoma is a group of eye diseases that lead to progressive damage of the optic nerve5 and can result in gradual, irreversible loss of vision, and eventually blindness, if left untreated.6 Glaucoma affects more than 2.2 million Americans7 and is the second-leading cause of preventable blindness worldwide.8 Simbrinza is a fixed-dose combination medication that offers a wide range of treatment possibilities due to its strong efficacy and ability to decrease elevated IOP by 21- 35%.1,2,3 In addition, it is the only available, fixed-dose combination ... Read more

Related support groups: Glaucoma, Glaucoma (Open Angle), Intraocular Hypertension, Brimonidine, Brinzolamide

Best Glaucoma Treatments Still a Puzzle, Task Force Reports

Posted 18 Feb 2013 by Drugs.com

MONDAY, Feb. 18 – Drugs and surgery can lower the hallmark inner-eye pressure characteristic of glaucoma – the second-leading cause of blindness in the United States. But research still hasn't identified the best ways to prevent significant vision loss and improve patient satisfaction, according to a prominent government medical group. The U.S. Preventive Services Task Force (USPSTF) reviewed dozens of studies and collective reviews on open-angle glaucoma, which accounts for about 90 percent of all cases, concluding there's inadequate evidence to directly compare the effectiveness of medical, surgical or laser treatments. The task force, comprised of 16 independent experts in prevention and evidence-based medicine, also said it couldn't determine whether glaucoma screening for adults without previous vision problems prevents blindness or enhances long-term health. "We know that ... Read more

Related support groups: Glaucoma, Glaucoma (Open Angle), Glaucoma/Intraocular Hypertension

U.S. Glaucoma Cases Jump 22 Percent Over Decade: Report

Posted 13 Dec 2012 by Drugs.com

THURSDAY, Dec. 13 – The prevalence of glaucoma in the United States is 22 percent higher than it was 10 years ago, a new report reveals. Researchers from Prevent Blindness America and the U.S. National Eye Institute reported that more than 2.7 million Americans aged 40 and older are affected by this eye disease, which can damage the optic nerve and gradually lead to blindness. Symptoms for glaucoma develop slowly, so the condition is also known as the "sneak thief of sight." The researchers pointed out in a joint news release that more than 50 percent of those who have glaucoma are not even aware of it. To increase awareness and educate people about glaucoma, Prevent Blindness America joined forces with other leading vision and eye health groups to declare January as National Glaucoma Awareness Month. Among the people at greatest risk for glaucoma are those who are older and have a ... Read more

Related support groups: Glaucoma, Glaucoma (Open Angle), Glaucoma/Intraocular Hypertension, Glaucoma (Narrow Angle)

Coffee Might Raise Glaucoma Risk: Study

Posted 4 Oct 2012 by Drugs.com

THURSDAY, Oct. 4 – People who drink at least three cups of coffee a day might be increasing their risk of developing glaucoma, which can lead to vision loss or blindness, according to Harvard University researchers. Specifically, caffeinated coffee appears to be associated with a type of glaucoma called exfoliation glaucoma, which is characterized by tiny fibers peeling from the eye's lens that can cause a pressure build-up, the researchers said. "While caffeinated coffee has several health benefits, drinking three or more cups of caffeinated coffee was found to be associated with increased risk of developing exfoliation glaucoma, particularly among those with a family history of glaucoma," said lead researcher Jae Hee Kang, assistant professor of medicine at the Channing Division of Network Medicine at Brigham and Women's Hospital in Boston. The increased risk was on the order of 66 ... Read more

Related support groups: Glaucoma, Glaucoma (Open Angle), Glaucoma/Intraocular Hypertension, Glaucoma (Narrow Angle)

Statins Tied to Reduced Glaucoma Risk

Posted 2 Oct 2012 by Drugs.com

TUESDAY, Oct. 2 – Researchers may have discovered yet another potential use for the widely used cholesterol-lowering drugs known as statins. In a new study, older people with high cholesterol who had taken statins for two years had an 8 percent reduced risk of developing open-angle glaucoma, the most common form of the eye disease. "That's a big deal," said Dr. Mark Fromer, an ophthalmologist at Lenox Hill Hospital in New York City, and eye surgeon director for the New York Rangers hockey team. "We're talking 3 million people [in the United States] who have glaucoma and half those people don't know it." Fromer was not involved with the study, which appears in the October issue of Ophthalmology. Glaucoma, which often affects people over 60, can lead to blindness. People at higher risk include those with a family member with glaucoma, blacks and older Hispanics, according to the Glaucoma ... Read more

Related support groups: Lipitor, Simvastatin, Crestor, Glaucoma, Pravastatin, Atorvastatin, Zocor, Lovastatin, Glaucoma (Open Angle), Rosuvastatin, Livalo, Red Yeast Rice, Pravachol, Lescol, Lescol XL, Mevacor, Pitavastatin, Altoprev, Fluvastatin, Baycol

Glaucoma Stent Approved

Posted 25 Jun 2012 by Drugs.com

MONDAY, June 25 – An ocular stent that's designed to reduce inner-eye pressure among people with mild or moderate open-angle glaucoma has been approved by the U.S. Food and Drug Administration. The iStent Trabecular Micro-Bypass Stent System is sanctioned for people with the disease who also have a cataract. The stent, along with surgery to remove the cataract, is designed to prevent damage to the optic nerve caused by high pressure inside the eye. Open-angle glaucoma, which causes this buildup of pressure, is among the leading causes of vision loss and blindness, the FDA said in a news release. The iStent is a small titanium tube that's designed to restore the natural draining of fluid from the eye, potentially decreasing intraocular pressure. The device was clinically studied among 239 people. Because the stent was used in cases where cataract surgery also was performed, ... Read more

Related support groups: Glaucoma, Glaucoma (Open Angle)

Research Gets Closer to Genetic Roots of Glaucoma

Posted 27 Apr 2012 by Drugs.com

FRIDAY, April 27 – Two genetic variations are linked to a common form of glaucoma, known as primary open-angle glaucoma, according to new research. Glaucoma affects about 2.2 million people in the United States, the U.S. National Eye Institute said in a news release. "Loss of vision from glaucoma, a common cause of blindness worldwide, is due to irreversible damage to the optic nerve," noted one expert, Dr. Mark Fromer, an ophthalmologist at Lenox Hill Hospital in New York City. "Glaucoma is usually associated with high eye pressure leading to optic nerve damage. There is also a form of glaucoma with normal pressure." In the new study, Janey Wiggs, of Harvard Medical School and Massachusetts Eye and Ear Infirmary in Boston, and colleagues analyzed the DNA sequences of more than 6,000 people. Half of them had primary open-angle glaucoma. This form of the disease is typically associated ... Read more

Related support groups: Glaucoma, Glaucoma (Open Angle)

Glaucoma Need Not Steal Sight, Experts Say

Posted 20 Apr 2012 by Drugs.com

FRIDAY, April 20 – Though glaucoma has been nicknamed the silent thief of sight, eye experts now say it generally doesn't have to be that way. "For most people, if you treat early, you should have vision for a lifetime," said Dr. Mark Fromer, an ophthalmologist at Lenox Hill Hospital and medical director of the Fromer Eye Centers, both in New York City, and the eye surgeon director for the New York Rangers hockey team. Glaucoma isn't just one disease but a group of conditions that cause damage to the optic nerve, which connects the eye to the brain. Left untreated, glaucoma can in fact cause blindness. And because the disease can progress for long periods undetected, experts stress that checkups and early detection are key to maintaining vision. Most forms of glaucoma develop because of increased pressure in the eye, according to the Glaucoma Foundation. High eye pressure, also known ... Read more

Related support groups: Glaucoma, Glaucoma (Open Angle)

FDA Approves Zioptan (tafluprost ophthalmic solution), Merck's Once-Daily, Preservative-Free Ophthalmic Medication

Posted 13 Feb 2012 by Drugs.com

WHITEHOUSE STATION, N.J., Feb. 13, 2012 – Merck, known as MSD outside the United States and Canada, announced today that the U.S. Food and Drug Administration (FDA) has approved Zioptan (tafluprost ophthalmic solution) 0.0015%, the first preservative-free prostaglandin analog ophthalmic solution. Zioptan (pronounced zye-OP-tan) is approved for reducing elevated intraocular pressure (IOP) in patients with open-angle glaucoma (OAG) or ocular hypertension. Open-angle glaucoma is the most common form of glaucoma, while ocular hypertension is a condition characterized by an increase in pressure inside the eye. "Prostaglandin analogs are often used as a first line of treatment to lower intraocular pressure in patients with open-angle glaucoma. The approval of Zioptan will provide a new, effective option to lower IOP," said George L. Spaeth, M.D., Wills Eye Institute, Philadelphia, "I a ... Read more

Related support groups: Glaucoma, Glaucoma (Open Angle), Glaucoma/Intraocular Hypertension

Mobius Therapeutics Receives Final FDA Approval for New Glaucoma Drug Mitosol

Posted 9 Feb 2012 by Drugs.com

ST. LOUIS, Feb. 9, 2012 /PRNewswire/ – Mobius Therapeutics, LLC, a St. Louis-based ophthalmic company, has received final approval from the U.S. Food and Drug Administration for the platform product, Mitosol. This initial indication is for the use of Mitosol in glaucoma surgery. With FDA approval, Mobius Therapeutics can start marketing and production efforts for Mitosol immediately. "The approval of Mitosol for use in glaucoma surgery represents the culmination of more than five years of work on the part of Mobius Therapeutics," said Ed Timm, President of Mobius Therapeutics. "It will provide surgeons, hospitals, and patients with enhanced convenience, safety, and consistency in the surgical treatment of glaucoma." Glaucoma is the second-leading cause of blindness in the United States. It is treated progressively, beginning with pharmaceuticals, then office intervention and finally ... Read more

Related support groups: Glaucoma, Glaucoma (Open Angle), Glaucoma/Intraocular Hypertension, Ophthalmic Surgery, Glaucoma (Narrow Angle), Glaucoma with Pupillary Block

Spending on Glaucoma Meds Rising in U.S., Study Finds

Posted 13 Jun 2011 by Drugs.com

MONDAY, June 13 – Spending on medications for Americans with the eye disease glaucoma has increased overall and especially among certain groups of patients, a new study finds. Researchers analyzed data from 1,404 patients aged 18 and older who used glaucoma medication between 2001 and 2006. The average amount spent per patient for glaucoma medications increased from $445 in 2001 to $557 in 2006. Among the groups most likely to be associated with significant increases in spending on glaucoma medications were women, people who had only public health insurance and those who hadn't completed high school. Spending on glaucoma medications was higher among patients with Medicare Part D coverage than among those with private insurance, said Dr. Byron L. Lam, of the Bascom Palmer Eye Institute in Miami, and colleagues. Glaucoma is a leading cause of blindness in the United States. As the ... Read more

Related support groups: Glaucoma, Glaucoma (Open Angle), Glaucoma/Intraocular Hypertension, Glaucoma (Narrow Angle), Glaucoma with Pupillary Block

Obesity Seems to Cut Women's Risk of Open-Angle Glaucoma

Posted 14 Feb 2011 by Drugs.com

MONDAY, Feb. 14 – Obesity may be associated with reduced risk of the eye disease open-angle glaucoma in women, but not in men, a new study suggests. Open-angle glaucoma is the most common form of glaucoma, a condition that causes damage to the optic nerve. In the study, researchers in the Netherlands analyzed data from 3,939 participants, aged 55 and older, who took part in the Rotterdam Study and who did not have open-angle glaucoma when the study began between 1991 and 1993. Over an average follow-up period of nearly 10 years, open-angle glaucoma developed in 108 participants (2.7 percent). The condition was most likely to occur in those who were older, had severe nearsightedness and in men, said Dr. Wishal Ramdas of the Erasmus Medical Center in Rotterdam, and colleagues. The investigators found that, for women, there was a link between increased body mass index (BMI) and pressure ... Read more

Related support groups: Obesity, Glaucoma (Open Angle)

Glaucoma Cases on the Rise in U.S.

Posted 11 Jul 2010 by Drugs.com

SUNDAY, July 11 – The changing makeup of the U.S. population is expected to lead to an increase in cases of glaucoma, the leading cause of vision loss in the country, experts say. A number of demographic and health trends have increased the number of Americans who fall into the major risk groups for glaucoma. These trends include: The aging of America Growth in the black and Hispanic populations The ongoing obesity epidemic And as more people become at risk, regular eye exams become increasingly important, eye experts say. Early detection of glaucoma is essential to preserving a person's sight, but eye exams are the only way to catch the disease before serious damage is done to vision. "The big thing about glaucoma is that it doesn't have any signs or symptoms," said Dr. Mildred Olivier of the Midwest Glaucoma Center in Hoffman Estates, Ill., and a board member of Prevent Blindness ... Read more

Related support groups: Glaucoma, Glaucoma (Open Angle), Glaucoma/Intraocular Hypertension, Glaucoma (Narrow Angle)

Confronting Glaucoma, Before It's Too Late

Posted 11 Jul 2010 by Drugs.com

SUNDAY, July 11 – Alan Leighton discovered he had glaucoma when he noticed a gray area of sight in his left eye. That was in 1992. "I think I had it a long time before that, but I didn't know until then," said Leighton, 68, a corporate treasurer who lives in Indianapolis. "Glaucoma is like that. It's sneaky." Leighton made an appointment with his ophthalmologist to see what was wrong. "We went for a bunch of tests, and he determined there was an issue with that eye, and that I had normal pressure glaucoma," he said. His response was unsentimental and pragmatic: His family has a history of glaucoma, so the news wasn't a total surprise. "I decided that we needed to take the most proactive methods we could," Leighton said. "I would go to the best people I could find and see what methods they had to address it and keep it from getting worse. I wanted to keep it from affecting my right eye, ... Read more

Related support groups: Glaucoma, Glaucoma (Open Angle), Glaucoma/Intraocular Hypertension, Glaucoma (Narrow Angle)

New Contact Lenses Could Improve Glaucoma Treatment

Posted 24 Mar 2010 by Drugs.com

WEDNESDAY, March 24 – A team of researchers has created special contact lenses for glaucoma patients that come loaded with vitamin E, using a design that could essentially lengthen the amount of time a medication bathes an afflicted eye. This strategy could reduce the significant waste of medication that happens with traditional eye drops, but so far the concept has only been tested in beagles. "Currently, the way we deliver medication to the eye is very bad and very ineffective," said study author Anuj Chauhan, an associate professor in the department of chemical engineering at the University of Florida in Gainesville. "And this approach is wonderful because it delivers drugs for a long period of time." Chauhan and his colleagues are to present their findings Wednesday at the American Chemical Society annual meeting in San Francisco. According to the Glaucoma Research Foundation, ... Read more

Related support groups: Glaucoma, Glaucoma (Open Angle), Glaucoma/Intraocular Hypertension, Glaucoma (Narrow Angle), Glaucoma with Pupillary Block

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