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GERD Blog

Related terms: Heartburn, Acid reflux, Esophageal Reflux, Gastroesophageal Reflux Disease, Pyrosis, Reflux, Heart Burn

Pfizer Statement on U.S. FDA Approval of Over-the-Counter Nexium 24HR

Posted 20 days ago by Drugs.com

Friday, March 28, 2014 - Today the U.S. Food and Drug Administration (FDA) approved over-the-counter Nexium 24HR (esomeprazole 20mg) marking a key step towards providing those who suffer from frequent heartburn broader access to a brand doctors and patients have trusted for years. In 2012, Pfizer acquired exclusive global rights from AstraZeneca to market non-prescription Nexium. The addition of Nexium 24HR to the Pfizer Consumer Healthcare portfolio expands the breadth of categories in which we help consumers better manage their health, and extends the value of the world’s leading prescription acid blocker brand. “Switching medicines, whenever appropriate, from prescription to non-prescription status improves access, empowers consumers to care for their own health and is an important strategy for Pfizer,” said Paul Sturman, President, Pfizer Consumer Healthcare. “The FDA approval of N ... Read more

Related support groups: GERD, Nexium, Heartburn Relief, Esomeprazole

Acid-Reflux Drugs Tied to Lower Levels of Vitamin B-12

Posted 10 Dec 2013 by Drugs.com

TUESDAY, Dec. 10, 2013 – People who take certain acid-reflux medications might have an increased risk of vitamin B-12 deficiency, according to new research. Taking proton pump inhibitors (PPIs) to ease the symptoms of excess stomach acid for more than two years was linked to a 65 percent increase in the risk of vitamin B-12 deficiency. Commonly used PPI brands include Prilosec, Nexium and Prevacid. Researchers also found that using acid-suppressing drugs called histamine-2 receptor antagonists – also known as H2 blockers – for two years was associated with a 25 percent increase in the risk of B-12 deficiency. Common brands include Tagamet, Pepcid and Zantac. "This study raises the question of whether or not people who are on long-term acid suppression need to be tested for vitamin B-12 deficiency," said study author Dr. Douglas Corley, a research scientist and gastroenterologist at ... Read more

Related support groups: GERD, Omeprazole, Nexium, Prilosec, Protonix, Zantac, Pantoprazole, Ranitidine, Dexilant, Prevacid, Pepcid, Lansoprazole, Aciphex, Famotidine, Heartburn Relief, Zegerid, Vitamin B12 Deficiency, Zantac 150, Pepcid AC, Rabeprazole

Generic Aciphex Approved to Treat Chronic Heartburn

Posted 8 Nov 2013 by Drugs.com

FRIDAY, Nov. 8 – The first generic versions of the anti-GERD drug Aciphex (rabeprazole sodium) have been approved by the U.S. Food and Drug Administration for people aged 12 and older, the agency said Friday. Gastroesophageal reflux disease (GERD), also known as chronic heartburn, is a very common disorder characterized by backward flow of stomach acid to the esophagus. This process could damage tissue in the esophagus, the tube that connects the throat and stomach. License to produce generic rabeprazole was granted to Dr. Reddy's Laboratories, Kremers Urban Pharmaceuticals, Lupin Pharmaceuticals, Mylan Pharmaceuticals, Teva Pharmaceuticals and Torrent Pharmaceuticals, the FDA said. The drug is among a class called proton-pump inhibitors, which are designed to reduce the amount of stomach acid produced. Generic drugs, the FDA stressed, are equivalent to the brand-name versions in ... Read more

Related support groups: GERD, Aciphex, Rabeprazole

Chronic Heartburn May Raise Odds for Throat Cancer: Study

Posted 23 May 2013 by Drugs.com

THURSDAY, May 23 – People who suffer from frequent heartburn may be at increased risk for cancers of the throat and vocal cords even if they don't smoke or drink alcohol, a new study says. Interestingly, common over-the-counter antacids seemed to protect against these cancers while prescription medications such as Prilosec, Nexium and Prevacid didn't, the researchers said. "There has been a controversy about whether heartburn contributes to cancers of the larynx or pharynx," said lead researcher Scott Langevin, a postdoctoral research fellow at Brown University in Providence, R.I. "And we found out that it does elevate the risk of these cancers. There is about a 78 percent increase in the risk for cancer in people who experience heavy heartburn," he said. "This is important in figuring out who to monitor more closely." The other finding, which Langevin called "surprising," was the ... Read more

Related support groups: Cancer, GERD, Omeprazole, Nexium, Prilosec, Indigestion, Prevacid, Lansoprazole, Tums, Caltrate, Milk of Magnesia, Calcium Carbonate, Sodium Bicarbonate, Esomeprazole, Mylanta, Prilosec OTC, Aluminum Hydroxide, Magnesium Hydroxide, Maalox, Prevacid SoluTab

FDA Approves Aciphex Sprinkle (rabeprazole sodium) For Use in Children Ages 1 to 11

Posted 16 Apr 2013 by Drugs.com

Woodcliff Lake, NJ, March 26, 2013 - Eisai Inc. announced today that the U.S. Food and Drug Administration (FDA) has approved Aciphex Sprinkle Delayed-Release Capsules 5mg and 10mg for the treatment of Gastroesophageal Reflux Disease (GERD) in children 1 to 11 years of age for up to 12 weeks. “We are proud to offer a new treatment option for young children who suffer from GERD,” said Lonnel Coats, president and CEO of Eisai Inc. “Eisai is committed to keeping the medical needs of patients and their families at the forefront of all that we do, as part of our human health care (hhc) corporate mission.” The approval of Aciphex Sprinkle is based on the results of a clinical trial of pediatric patients 1 to 11 years of age. The clinical trial was a multicenter, double-blind, parallel-group study conducted in 127 pediatric patients with endoscopically-proven GERD that consisted of a 12-week ... Read more

Related support groups: GERD, Aciphex, Rabeprazole, Gastroesophageal Reflux Disease

Health Tip: Before You Take This Heartburn Medication...

Posted 5 Apr 2013 by Drugs.com

-- A proton pump inhibitor, a drug commonly taken for heartburn, may cause side effects. The American Academy of Family Physicians lists these factors to consider before using a proton pump inhibitor (PPI): If you're a postmenopausal woman, talk with your doctor because a PPI could increase your risk for bone fractures. If you've been treated for a C. difficile infection, check with your doctor because PPIs may increase the risk of the infection returning. If you have problems with your immune system or are elderly, check with your doctor because PPIs may increase the risk of pneumonia. Read more

Related support groups: GERD, Omeprazole, Nexium, Prilosec, Protonix, Pantoprazole, Dexilant, Prevacid, Lansoprazole, Aciphex, Zegerid, Rabeprazole, Esomeprazole, Prilosec OTC, Prevacid SoluTab, Dexlansoprazole, Kapidex, Zegerid OTC, Omeprazole/Sodium Bicarbonate, Protonix IV

Parents Will Push for Medication, Even If Doc Says Not Needed

Posted 1 Apr 2013 by Drugs.com

MONDAY, April 1 – When doctors use quick-and-easy disease labels to sum up symptoms of concern in an otherwise healthy infant, parents are more apt to want to treat their child with some type of medication, even if they're told that drugs won't help, new research says. The finding was gleaned from the results of a survey administered in a general pediatric clinic setting. The poll had asked parents how they would react to being told that their child's excessive crying and spitting amounted to a diagnosis of gastroesophageal reflux disease (GERD), rather than being given no specific disease label at all. The study highlights the powerful impact that a physician's choice of words can have on parental decision-making, while emphasizing the importance of good doctor-patient/parent communication. "The disease label seems to send the message that there is an illness that requires medical ... Read more

Related support groups: GERD

Health Tip: Don't Let GERD Interrupt Your Sleep

Posted 6 Mar 2013 by Drugs.com

-- Gastroesophageal reflux disease (GERD) is a gastrointestinal condition that often triggers uncomfortable nighttime heartburn that affects sleep. The National Sleep Foundation lists these suggestions to help keep GERD under control so you can get a better night's sleep: Don't lie down after eating a big meal. Try to eat smaller meals instead of large ones; practice an upright but relaxed posture as you eat. Try to avoid onions, chocolate and high-fat foods, as well as alcohol. Don't take potassium supplements. Take medications while sitting in an upright position and swallow with a lot of water. Read more

Related support groups: GERD

Heartburn Meds May Often Be Taken for Too Long, at Too-High Doses

Posted 22 Feb 2013 by Drugs.com

FRIDAY, Feb. 22 – U.S. veterans with chronic heartburn are often prescribed higher-than-recommended doses of medicines to control the condition and many are kept on the drugs far too long, according to a new study. Researchers looked at 1,600 veterans who were diagnosed with chronic heartburn – also known as gastroesophageal reflux disease (GERD) – and prescribed a type of drug called a "proton pump inhibitor," such as Prilosec (omeprazole). GERD arises when the ring of muscle between the esophagus and stomach fails to close properly, allowing stomach acids to splash up into the esophagus. The main symptom is chronic heartburn. These drugs – which also include Prevacid (lansoprazole) and Nexium (esomeprazole) – are among the most widely used drugs in the United States and provide relief for many patients with chronic heartburn. However, proper prescribing is required to avoid ... Read more

Related support groups: GERD, Omeprazole, Nexium, Prilosec, Protonix, Pantoprazole, Dexilant, Prevacid, Lansoprazole, Aciphex, Zegerid, Rabeprazole, Esomeprazole, Prilosec OTC, Prevacid SoluTab, Dexlansoprazole, Kapidex, Zegerid OTC, Omeprazole/Sodium Bicarbonate, Protonix IV

Magnetic Implant May Ease Chronic Acid Reflux

Posted 20 Feb 2013 by Drugs.com

WEDNESDAY, Feb. 20 – An implanted magnetic device could offer a new treatment option for people with chronic heartburn that is not controlled with medication, a small study suggests. The study, reported in the Feb. 21 issue of the New England Journal of Medicine, tested a newer approach to taming stubborn cases of gastroesophageal reflux disease (GERD) – one of the most common health conditions diagnosed in the United States. GERD arises when the ring of muscle between the esophagus and stomach fails to close properly, allowing stomach acids to splash up into the esophagus. The main symptom is chronic heartburn. For people who have frequent heartburn – more than twice a week – the go-to medications are the so-called proton pump inhibitors, such as Prilosec, Prevacid and Nexium. But studies estimate that up to 40 percent of people on those drugs do not get enough relief. The new ... Read more

Related support groups: GERD

Chronic Heartburn Could Spur Asthma in Some Patients

Posted 25 Jan 2013 by Drugs.com

FRIDAY, Jan. 25 – Chronic heartburn is a major cause of asthma in adults, a new study suggests. The finding could help add asthma to the known health risks – including esophageal cancer – already associated with chronic heartburn, which is formally known as gastroesophageal reflux disease (GERD) and is one of the most common digestive disorders in Western nations. GERD occurs when a muscle at the end of the esophagus fails to close properly. This allows stomach contents to leak back (reflux) into the esophagus and irritate it. GERD symptoms include frequent heartburn, chest discomfort, dry cough, difficulty swallowing, hoarseness or sore throat, and regurgitation of food. In this study, researchers used a new, specially designed catheter that measures levels of acid reflux exposure within the patient's airway. They believe that this new method (known by the acronym HMII) was much ... Read more

Related support groups: GERD, Asthma

New Guidelines Urge Limiting Endoscopy for GERD

Posted 4 Dec 2012 by Drugs.com

TUESDAY, Dec. 4 – Heartburn can usually be diagnosed and managed without the use of an invasive procedure called an upper endoscopy, according to new recommendations for doctors. Many physicians perform upper endoscopies to screen people who have had long-term heartburn for cancer of the esophagus because heartburn, also known as gastroesophageal reflux disease (GERD), can raise the risk of this cancer. Upper endoscopy involves placing a long, flexible tube down the throat that takes pictures of the esophagus, stomach and other parts of the gastrointestinal tract. The new guidelines by the American College of Physicians (ACP) recommend against screening the general population with GERD this way, partly because the cancer is rare even in this at-risk group. "It's an area of uncertainty if screening prevents death from cancer," said guidelines author Dr. Nicholas Shaheen, director of the ... Read more

Related support groups: GERD, Diagnosis and Investigation, Endoscopy or Radiology Premedication

Stimulation Device for Esophagus Might Ease GERD Symptoms

Posted 23 Oct 2012 by Drugs.com

TUESDAY, Oct. 23 – Electric stimulation of the esophagus shows promise as a novel way to provide symptom relief for patients struggling with chronic gastroesophageal reflux (GERD), three new studies suggest. The device's effectiveness, which was tested in very small groups of patients, was measured by two independent study teams – one American and one Dutch. Both teams presented their findings Monday at the American College of Gastroenterology annual meeting, in Las Vegas. The goal: to develop a new therapy for GERD patients who are reluctant to undergo more invasive stomach surgery, or for whom a lifelong regimen of acid-suppression drugs known as proton pump inhibitors is either unappealing or not particularly effective. "Most patients who have reflux symptoms are treated by meds that suppress acid production in the stomach," explained one of the American team's co-authors, Dr. Edy ... Read more

Related support groups: GERD

Untreated Heartburn May Raise Risk for Esophageal Cancer, Study Says

Posted 25 Jul 2012 by Drugs.com

WEDNESDAY, July 25 – Rates of esophageal cancer have surged due to a lack of awareness about what causes the disease and how it can be prevented, experts say. The esophagus is the muscular tube that carries food and liquid from the mouth to the stomach. There were six times as many cases of esophageal cancer in 2001 as there were in 1975, according to a team from the University of California, Los Angeles. The researchers noted that one key way people can reduce their risk for the disease is by managing heartburn and acid reflux, often called gastroesophageal reflux disease, or GERD. "Obesity and poor diet have spiked the numbers suffering from acid reflux," Dr. V. Raman Muthusamy, associate clinical professor of medicine and endoscopy director at the UCLA Center for Esophageal Disorders, said in a university news release. If left untreated, GERD can cause stomach acid to wash ... Read more

Related support groups: GERD, Barrett's Esophagus, Esophageal Carcinoma

Chronic Heartburn May Boost Risk for Esophageal Cancer

Posted 18 May 2012 by Drugs.com

FRIDAY, May 18 – Inflammation caused by chronic heartburn may increase the risk of esophageal cancer, a new study finds. The condition – formally known as gastroesophageal reflux disease (GERD) – occurs when a muscle at the end of the esophagus doesn't close properly, allowing stomach contents to leak back into the esophagus and irritate it. GERD can lead to changes in the tissue lining the esophagus, a condition called Barrett's esophagus, often a precursor to esophageal cancer. In the study, researchers looked at nearly 34,000 GERD patients in Denmark and found that 77 percent had inflammation of the lining of the esophagus, a condition called erosive reflux disease. During an average follow-up time of 7.4 years, 0.11 percent of patients developed esophageal cancer. The incidence of esophageal cancer among GERD patients with erosive disease was much higher than that of the general ... Read more

Related support groups: GERD, Barrett's Esophagus, Esophageal Carcinoma

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