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Postmenopausal Estrogen Therapy Tied to Lower Glaucoma Risk

Posted 30 Jan 2014 by Drugs.com

THURSDAY, Jan. 30, 2014 – Women who take estrogen-only hormone-replacement therapy to relieve menopausal symptoms might also be reducing their risk for a common form of the eye disease glaucoma, according to new research. "Ours is one of the first ... studies to find estrogen-containing hormone-replacement therapy was associated with a reduction in glaucoma risk," said study researcher Dr. Joshua Stein, an assistant professor of ophthalmology at the University of Michigan. Other studies, however, have come up with conflicting results, Stein said. In his study, he looked at insurance-claims data for women aged 50 and older who were enrolled in a managed care plan for at least four years. The women visited an eye care provider at least twice from 2001 to 2009. He evaluated information on more than 152,000 women, about 60,000 of whom had at least one prescription for estrogen-only ... Read more

Related support groups: Estradiol, Premarin, Glaucoma, Estrace, Postmenopausal Symptoms, Ethinyl Estradiol, Vivelle, Vagifem, Climara, Estrace Vaginal Cream, Vivelle-Dot, Estring, Estradiol Patch, Evamist, Premarin Vaginal, Enjuvia, Minivelle, Cenestin, Femring, Estraderm

Avoidance of Hormone Therapy May Have Harmed Hysterectomy Patients: Study

Posted 19 Jul 2013 by Drugs.com

THURSDAY, July 18 – Widespread discontinuance of hormone replacement therapy in the past decade possibly contributed to the deaths of nearly 50,000 U.S. women who had had a hysterectomy, a new analysis contends. The findings refer only to women who've had a hysterectomy and then experience menopausal symptoms, the researchers emphasized. "In women who have had a hysterectomy who have symptoms of hormone deficiency [such as hot flashes], it can be lifesaving for them to take estrogen," said review author Dr. Philip Sarrel, of Yale University School of Medicine. For women between the ages of 50 and 59, estrogen-only therapy after a hysterectomy reduces the risk of heart attack and death, Sarrel said. "The main reduction [in deaths] is the reduction in heart attacks, but there is also a clear reduction in the incidence of breast cancer and deaths from breast cancer," Sarrel said. The use ... Read more

Related support groups: Estradiol, Hysterectomy, Premarin, Estrace, Ethinyl Estradiol, Vivelle, Vagifem, Climara, Estrace Vaginal Cream, Vivelle-Dot, Estring, Estradiol Patch, Evamist, Premarin Vaginal, Enjuvia, Minivelle, Cenestin, Femring, Estraderm, Menest

HRT in Early 50s Has No Impact on Women's Memory, Thinking: Study

Posted 24 Jun 2013 by Drugs.com

MONDAY, June 24 – Women aged 50 to 55 who take hormone therapy to relieve the symptoms of menopause can expect no benefit or risk to their memory or other thinking skills due to the treatment, according to new research. The study was done to evaluate more closely the effect of the hormone treatment on women during the years menopause typically begins. An earlier study, the Women's Health Initiative Memory Study, found that the hormone treatment produced deficits in thinking ability when given to women 65 years old and older. And other WHI research has found that hormone therapy can increase the risk of breast cancer, heart disease and stroke but protect against osteoporosis, the brittle bone disease. Based on that research, many experts now suggest that the hormone therapy be taken, if needed, to relieve menopausal symptoms on a short-term basis. In the new study, the focus was on ... Read more

Related support groups: Estradiol, Premarin, Estrace, Postmenopausal Symptoms, Ethinyl Estradiol, Vivelle, Vagifem, Climara, Estrace Vaginal Cream, Vivelle-Dot, Estring, Estradiol Patch, Evamist, Premarin Vaginal, Enjuvia, Minivelle, Cenestin, Femring, Estraderm, Menest

Sex Change Hormonal Therapy Deemed Safe

Posted 20 Jun 2013 by Drugs.com

THURSDAY, June 20 – For transsexual people who seek hormonal therapy, a new study offers some welcome news: short-term use of the treatment is safe and effective. Surgery and hormone therapy are options for transsexual (also called transgender) people who want to change their external appearance in order to match what they feel is their true gender. Hormone therapy involves taking large doses of male or female sex hormones, which has led to concerns about possible health risks. The study assessed the effects of short-term hormone therapy among 45 transsexual men and 42 transsexual women at four European centers that specialize in such treatment. The female-to-male transsexuals received a form of the male sex hormone testosterone, and the male-to-female transsexuals received treatment to lower their male hormone levels along with a form of the female sex hormone estrogen. Treatment ... Read more

Related support groups: Testosterone, Estradiol, AndroGel, Estrace, Testim, Axiron, Vivelle, Climara, Vivelle-Dot, Androderm, Estradiol Patch, Fortesta, Evamist, Minivelle, Depo-Testosterone, Estraderm, Femring, Testopel, Divigel, Delatestryl

FDA Medwatch Alert: Olympia Pharmacy Sterile Compounded Products: Recall - Concerns About Sterility Assurance

Posted 5 Jun 2013 by Drugs.com

  [Posted 05/30/2013] ISSUE: Lowlite Investments d/b/a Olympia Pharmacy ("Lowlite") notified the public of a voluntary multi-state recall of all sterile drug products compounded by the pharmacy that have not reached the expiration date listed on the product. The recall is being initiated due to concerns associated with prior quality control procedures that impacted sterility assurance. In the event a sterile product is compromised patients are at risk for serious and possible life threatening infections. The recall includes all sterile products that Olympia Pharmacy supplied to patients and offices of licensed medical professionals with a use by date of 09/25/2013 or earlier. Olympia Pharmacy will be notifying customers by phone, fax, or mail to return the products to the pharmacy. BACKGROUND: To date, Lowlite has received no reports of injury or illness associated with the use of the a ... Read more

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Estrogen Levels Tied to Risk for Sudden Cardiac Death in Study

Posted 10 May 2013 by Drugs.com

FRIDAY, May 10 – Higher levels of the hormone estrogen are associated with an increased risk of sudden cardiac death in men and women, a new study suggests. Sudden cardiac death can occur when the heart suddenly and unexpectedly stops beating (sudden cardiac arrest). Each year in the United States, more than 350,000 people die of sudden cardiac death. Researchers examined data from people in Portland, Ore., who suffered sudden cardiac death or had coronary artery disease. Tests of plasma taken at the time of death or during a doctor's visit indicated that both groups had a similar proportion of common heart risk factors such as diabetes, obesity, high blood pressure and high cholesterol. But levels of testosterone were much lower among men and slightly higher among women in the sudden cardiac death group compared to those with coronary artery disease, according to the study, which is ... Read more

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Artificial Ovaries Could Potentially Deliver Hormone Therapy

Posted 29 Mar 2013 by Drugs.com

FRIDAY, March 29 – It might be possible to create artificial ovaries in the laboratory to provide a more natural form of hormone replacement therapy (HRT) for women, researchers report. As well as producing eggs, ovaries secrete hormones that are important for bone and heart health. Production of these hormones stops due to menopause, as well as surgical removal of the ovaries, chemotherapy and radiation treatments for certain types of cancer. There are hormone replacement medications, but long-term use of the drugs is generally avoided due to the increased risk of heart disease and breast cancer, according to the authors of a new study published in the March issue of the journal Biomaterials. In this study, a team from the Institute of Regenerative Medicine at Wake Forest Baptist Medical Center reported that ovaries created in the lab showed sustained release of the female sex ... Read more

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Hormone Pills in Menopause May Carry Gallstone Side Effects

Posted 19 Mar 2013 by Drugs.com

TUESDAY, March 19 – Taking estrogen pills increases a menopausal woman's risk of needing gallbladder surgery to treat complications of gallstones, according to a new study. But there does not appear to be an increased risk for women who take estrogen through skin patches or gels, called transdermal methods. The study appears March 18 in the CMAJ (Canadian Medical Association Journal). Researchers analyzed data gathered from more than 70,000 women in France between 1992 and 2008. In France, transdermal hormone therapy is preferred, while oral hormone therapy (pills or tablets) tends to be favored in North America and the United Kingdom, a journal news release noted. "Complicated gallstone disease should be added to the list of potential adverse events to be considered when balancing the benefits and risks associated with menopausal hormone therapy," said Dr. Antoine Racine, of the ... Read more

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Short-Term, Early HRT May Cut Women's Alzheimer's Risk: Study

Posted 24 Oct 2012 by Drugs.com

WEDNESDAY, Oct. 24 – It is said that timing is everything. When it comes to taking hormone replacement therapy, that may indeed be true. A new study has found that taking hormone replacement therapy within five years of menopause may reduce the risk of developing Alzheimer's disease by 30 percent compared to women who have not used hormone therapy. The researchers set out to better understand why some previous studies had shown hormones were effective in reducing Alzheimer's risk while others had not. The Women's Health Initiative Memory Study, a large, multicenter trial, was stopped prematurely in 2002 due to concerns that the hormones might be raising the risks of cardiovascular disease, cancer and dementia. "The Women's Health study put a cloud over doing further research," said Peter Zandi, author of the latest study and an associate professor at Johns Hopkins University Bloomberg ... Read more

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Hormone Replacement Therapy: Safe or Not?

Posted 24 Oct 2012 by Drugs.com

WEDNESDAY, Oct. 24 – Is hormone replacement therapy safe or not? It has taken a decade of research to arrive at a conclusion that is far from definitive: The evidence suggests it may help in the short term to manage hot flashes and other symptoms of menopause in some younger, healthy women. But, taking it for long periods of time or later in menopause to help prevent certain chronic diseases isn't recommended. On Monday, the U.S. Preventive Services Task Force once again backed the idea that long-term use later in menopause is unwise when it released recommendations that said the increased health risks outweighed the benefits of using the treatment in that medical scenario. That was not always the prevailing view in the medical community, however. For years, it was common for women suffering from hot flashes, night sweats and other life-disrupting symptoms of menopause to go on hormone ... Read more

Related support groups: Hot Flashes, Menopausal Disorders, Estradiol, Premarin, Estrace, Postmenopausal Symptoms, Vivelle, Prempro, Vagifem, Climara, Estrace Vaginal Cream, Estratest, Vivelle-Dot, Estring, Natazia, Perimenopausal Symptoms, Estradiol Patch, Evamist, Premarin Vaginal, Enjuvia

New Research Suggests HRT May Lower Heart Risks

Posted 10 Oct 2012 by Drugs.com

WEDNESDAY, Oct. 10 – New research suggests that women who take hormone replacement therapy in the early stages of menopause may have a reduced risk of heart attack, heart failure or dying. This apparent benefit comes without a heightened risk of cancer or blood clots, the Danish researchers said. These health risks have long been a concern of menopausal women and their doctors when considering hormone therapy. The study, published Oct. 9 in the BMJ, even found evidence of a trend toward a lower risk of breast cancer, although this was not statistically significant, said study author Dr. Louise Lind Schierbeck. However, two doctors not associated with the study said the findings weren't enough to convince them to recommend hormone replacement therapy (HRT) to head off heart problems. But they – and many doctors – would prescribe low doses of the therapy for short durations to treat ... Read more

Related support groups: Heart Attack, Estradiol, Heart Failure, Premarin, Congestive Heart Failure, Progesterone, Estrace, Postmenopausal Symptoms, Vivelle, Prempro, Prometrium, Climara, Myocardial Infarction, Vivelle-Dot, Estradiol Patch, Evamist, Enjuvia, Cenestin, Crinone, Femring

Medical Groups Agree on Use of Hormone-Replacement Therapy

Posted 9 Jul 2012 by Drugs.com

MONDAY, July 9 – A coalition of leading medical groups has concluded that hormone-replacement therapy can be useful and safe for many women suffering from the symptoms of menopause. The coalition includes 15 medical groups, including the North American Menopause Society, the American Society for Reproductive Medicine, the Endocrine Society and the American Academy of Family Physicians. The goal of the statement, released Monday, is to reassure women and doctors that hormone-replacement therapy (HRT) is acceptable and relatively safe for healthy, symptomatic, recently postmenopausal women, the statement authors said in a news release. "Over the last 10 years, there has been a complete abandonment of hormone therapy in some settings accompanied by reluctance to treat women who would benefit from relief of their [menopausal] symptoms. As a result, some women have sought unproven ... Read more

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HRT Update: Therapy May Reduce Fractures, Boost Some Risks

Posted 28 May 2012 by Drugs.com

MONDAY, May 28 – Updated evidence on hormone replacement therapy for menopausal women presents good news for those at risk of osteoporosis, but a mixed bag of results regarding breast cancer and other chronic diseases. While estrogen-only and estrogen-plus-progestin formulations reduce the risk of fractures, both increase the odds for stroke and other conditions including gallbladder disease, according to a new update of available evidence compiled for the U.S. Preventive Services Task Force, an independent expert panel that is revising its guidelines. Estrogen-plus-progestin therapy raises the risk of breast cancer and probable dementia, while estrogen alone reduces the risk of breast cancer, the researchers found. "We looked at all the published studies on hormone therapy for the prevention of chronic disease," said Dr. Heidi Nelson, who led the update. "What is new here is, we've ... Read more

Related support groups: Estradiol, Premarin, Estrace, Postmenopausal Symptoms, Ethinyl Estradiol, Vivelle, Vagifem, Climara, Estrace Vaginal Cream, Vivelle-Dot, Fracture, bone, Estring, Estradiol Patch, Evamist, Premarin Vaginal, Enjuvia, Cenestin, Femring, Estraderm, Menest

Birth Control Pills, HRT Tied to Digestive Ills

Posted 21 May 2012 by Drugs.com

MONDAY, May 21 – The use of oral contraceptives by younger women or hormone therapy by older women may be linked with inflammatory bowel disease, new research indicates. Birth control pills are associated with a higher risk for Crohn's disease, said researcher Dr. Hamed Khalili, a clinical and research fellow of gastroenterology at Massachusetts General Hospital in Boston. Crohn's causes inflammation of the lining and wall of the large or small intestine, or both. The lining can become so inflamed it bleeds. Hormone replacement therapy taken by some women after menopause is linked with ulcerative colitis, the study found. It is a disease of the colon (large intestine) or rectum. It causes diarrhea, abdominal cramping and rectal bleeding. Khalili presented the findings Sunday at the Digestive Disease Week meeting, in San Diego. Of the two links they found, Khalili said, the association ... Read more

Related support groups: Birth Control, Contraception, Plan B, Sprintec, Mirena, Implanon, Provera, NuvaRing, Tri-Sprintec, Yasmin, Depo-Provera, Ortho Tri-Cyclen, Loestrin 24 Fe, Lutera, Microgestin Fe 1/20, Estradiol, TriNessa, Ortho Evra, Mononessa, Nexplanon

Long-Term Estrogen Therapy Does Up Breast Cancer Risk: Study

Posted 2 Apr 2012 by Drugs.com

SUNDAY, April 1 – Several weeks after a study suggested that women who take estrogen-only hormone replacement to treat menopause symptoms may be at lower risk for developing breast cancer, another, much-larger study finds that when used for longer than 10 years, estrogen-only regimens actually raise a woman's long-term risk for breast cancer. The new study was funded by the National Cancer Institute, part of the U.S. National Institutes of Health, whereas the previous one was partially funded by drug manufacturer Wyeth. Researchers evaluated follow-up data from the Nurse's Health Study collected from 1980 through 2008. The women in the study were 30 to 55 years old in 1976. Overall, the risk for breast cancer was 88 percent higher among women who had taken estrogen plus progesterone for 10 to 14.9 years, compared to women who did not. This risk more than doubled for women who used ... Read more

Related support groups: Breast Cancer, Estradiol, Premarin, Estrace, Ethinyl Estradiol, Vivelle, Vagifem, Climara, Estrace Vaginal Cream, Vivelle-Dot, Estring, Estradiol Patch, Evamist, Premarin Vaginal, Enjuvia, Cenestin, Femring, Estraderm, Menest, Ogen

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