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Common Cold Meds May Pose Health Threats

Posted 19 Mar 2014 by Drugs.com

WEDNESDAY, March 19, 2014 – Over-the-counter sinus and pain remedies that combine two common ingredients – phenylephrine and acetaminophen – might cause serious side effects such as high blood pressure, dizziness and tremors, New Zealand researchers warn. These side effects occur because acetaminophen (the main ingredient in Tylenol) boosts the effects of phenylephrine, according to a report in the March 20 issue of the New England Journal of Medicine. Products containing this drug combination include Tylenol Sinus, Sudafed PE Sinus, Benadryl Allergy Plus Sinus and Excedrin Sinus Headache. "What we found was surprising because it hasn't been studied or reported," said lead researcher Hartley Atkinson, managing director of AFT Pharmaceuticals, Ltd., in Auckland. Phenylephrine, which replaced pseudoephedrine in many over-the-counter medications, relieves nasal congestion from colds, ... Read more

Related support groups: Percocet, Vicodin, Norco, Tylenol, Lortab, Acetaminophen, Sta-D, Fioricet, Paracetamol, Darvocet-N 100, Endocet, Excedrin, Cold Symptoms, Tylenol PM, Phenylephrine, NyQuil, Ultracet, Tylenol with Codeine, Acetaminophen/Hydrocodone, Roxicet

Use of Tylenol in Pregnancy Tied to Higher ADHD Risk in Child

Posted 24 Feb 2014 by Drugs.com

MONDAY, Feb. 24, 2014 – Expectant mothers suffering from fever or headache may face a new dilemma when they open the medicine cabinet. Pregnant women who take acetaminophen – best known under the brand name Tylenol – might be more likely to have a child with attention deficit-hyperactivity disorder (ADHD), a new long-term study suggests. Acetaminophen is the most commonly used over-the-counter medication for pregnant women who experience fever or pain. Children whose mothers took acetaminophen while pregnant had up to a 40 percent higher risk of being diagnosed with ADHD, according to the research, which involved more than 64,000 Danish mothers and their children. The kids were born between 1996 and 2002. By the age of 7, these children also were more likely to use ADHD medication and exhibit ADHD-like behavior problems, according to the study, published Feb. 24 in the journal JAMA ... Read more

Related support groups: Attention Deficit Hyperactivity Disorder (ADHD), Percocet, Vicodin, Norco, Tylenol, Lortab, Acetaminophen, Fioricet, Paracetamol, Darvocet-N 100, Endocet, Excedrin, Tylenol PM, NyQuil, Ultracet, Tylenol with Codeine, Acetaminophen/Hydrocodone, Roxicet, Percocet 10/325, Tylenol with Codeine 3

FDA Warns Against Prescription Drugs With High Levels of Acetaminophen

Posted 15 Jan 2014 by Drugs.com

WEDNESDAY, Jan. 15, 2014 – The U.S. Food and Drug Administration has asked doctors to stop prescribing painkillers that contain more than 325 milligrams of acetaminophen because of reports of severe liver damage. Prescription painkillers, which include Vicodin and Percocet, are commonly given for pain following acute injuries, operations or dental procedures and they often contain acetaminophen. However, many over-the-counter medications also contain acetaminophen. The FDA first tackled this issue in January 2011, when it asked drug makers to stop making prescription painkillers that contained more than 325 milligrams of acetaminophen per dose. Accidental overdoses from using these products contributes to nearly half of all cases of acetaminophen-related liver failure in the United States, the agency said in a statement issued Tuesday. Most cases of severe liver injury occurred in ... Read more

Related support groups: Percocet, Vicodin, Norco, Tylenol, Lortab, Acetaminophen, Fioricet, Paracetamol, Darvocet-N 100, Endocet, Excedrin, Tylenol PM, NyQuil, Ultracet, Tylenol with Codeine, Acetaminophen/Hydrocodone, Roxicet, Percocet 10/325, Tylenol with Codeine 3, Lorcet 10/650

FDA Medwatch Alert: Acetaminophen Prescription Combination Drug Products with more than 325 mg: FDA Statement - Recommendation to Discontinue Prescribing and Dispensing

Posted 14 Jan 2014 by Drugs.com

ISSUE: FDA is recommending health care professionals discontinue prescribing and dispensing prescription combination drug products that contain more than 325 milligrams (mg) of acetaminophen per tablet, capsule or other dosage unit. There are no available data to show that taking more than 325 mg of acetaminophen per dosage unit provides additional benefit that outweighs the added risks for liver injury. Further, limiting the amount of acetaminophen per dosage unit will reduce the risk of severe liver injury from inadvertent acetaminophen overdose, which can lead to liver failure, liver transplant, and death.   Cases of severe liver injury with acetaminophen have occurred in patients who: • took more than the prescribed dose of an acetaminophen-containing product in a 24-hour period; • took more than one acetaminophen-containing product at the same time; or • drank alcohol while taking a ... Read more

Related support groups: Pain, Percocet, Vicodin, Norco, Tylenol, Lortab, Acetaminophen, Fever, Fioricet, Paracetamol, Darvocet-N 100, Endocet, Excedrin, Tylenol PM, NyQuil, Ultracet, Tylenol with Codeine, Acetaminophen/Hydrocodone, Roxicet, Percocet 10/325

Health Tip: Don't Take Too Much Acetaminophen

Posted 3 Jan 2014 by Drugs.com

-- If you're plagued with a headache, sinus congestion or body aches, you may find the common pain reliever acetaminophen in more than one medication you take for relief. After all, acetaminophen is found in more than 600 over-the-counter and prescription medications, the U.S. Food and Drug Administration says. The FDA makes these recommendations on how to make sure you don't take too much acetaminophen, the active ingredient in Tylenol: Adults should not exceed 4,000 milligrams per day. Never take more than the recommended dose of any medication. Avoid taking multiple over-the-counter medications that contain acetaminophen. Don't take a prescription drug that contains acetaminophen along with an OTC medication that contains it. Read more

Related support groups: Headache, Percocet, Vicodin, Norco, Tylenol, Lortab, Acetaminophen, Fioricet, Paracetamol, Darvocet-N 100, Endocet, Excedrin, Cold Symptoms, Tylenol PM, NyQuil, Ultracet, Tylenol with Codeine, Acetaminophen/Hydrocodone, Roxicet, Percocet 10/325

Tylenol and Alcohol a Bad Mix, Study Suggests

Posted 4 Nov 2013 by Drugs.com

MONDAY, Nov. 4 – Combining Tylenol and even light consumption of alcohol can more than double someone's risk of kidney disease, researchers say. Taking the recommended dose of Tylenol, also known by its generic name acetaminophen, combined with a small to moderate amount of alcohol produces a 123 percent increased risk of kidney disease, according to a new preliminary study. "Most people take this medication without any input from pharmacists or physicians, and that's where the public-health concern is," said lead researcher Harrison Ndetan, an associate professor for research and biostatistics at Parker University in Dallas. "People buy acetaminophen over the counter, and they also are casual alcohol users, and they don't know that there is a harmful interaction." The study, scheduled for presentation Monday at the American Public Health Association's annual meeting in Boston, ... Read more

Related support groups: Percocet, Vicodin, Norco, Tylenol, Lortab, Acetaminophen, Fioricet, Paracetamol, Darvocet-N 100, Endocet, Excedrin, Tylenol PM, NyQuil, Ultracet, Tylenol with Codeine, Acetaminophen/Hydrocodone, Roxicet, Percocet 10/325, Tylenol with Codeine 3, Lorcet 10/650

Tylenol to Come With New Warning

Posted 4 Sep 2013 by Drugs.com

September 3, 2013 – Caps on bottles of the popular pain reliever Tylenol that are sold in the United States will soon come with warnings alerting consumers to the potential for liver failure and even death, the Associated Press reported Thursday. The warning will state that Tylenol's active ingredient is acetaminophen, the nation's leading cause of sudden liver failure. The new cap is designed to alert consumers who may not read similar warnings that already appear in small print on the product's label, the AP said. In addition to Tylenol, acetaminophen is contained in more than 600 over-the-counter products used by nearly one in four American adults every week. Those other products include such popular brands as Nyquil cold formula, Excedrin pain tablets and Sudafed sinus pills, the AP reported. Tylenol's maker, Johnson & Johnson, said the warning will appear on the cap of each new ... Read more

Related support groups: Vicodin, Norco, Tylenol, Lortab, Acetaminophen, Fioricet, Paracetamol, Darvocet-N 100, Excedrin, Tylenol PM, NyQuil, Ultracet, Tylenol with Codeine, Acetaminophen/Hydrocodone, Tylenol with Codeine 3, Lorcet 10/650, Panadol, Coricidin, Vicodin ES, Excedrin Migraine

FDA Warns of Rare Skin Reactions to Acetaminophen

Posted 2 Aug 2013 by Drugs.com

FRIDAY, Aug. 2 – The widely used painkiller acetaminophen, best known as Tylenol, can cause rare but serious skin reactions and a warning about this danger will be added to product labels, the U.S. Food and Drug Administration said Thursday. Acetaminophen is also often used in combination with other medicines, including opioids for pain and medicines to treat colds, coughs, allergy, headache and sleeping problems. According to the FDA, acetaminophen can trigger three serious skin reactions. Two of them – Stevens-Johnson Syndrome and toxic epidermal necrolysis – usually require hospitalization and can be lethal. The reactions usually begin with flu-like symptoms followed by rash, blistering and extensive damage to the skin surface. Recovery can take weeks or months, and possible complications include scarring, skin color changes, blindness and damage to internal organs. A third skin ... Read more

Related support groups: Vicodin, Norco, Tylenol, Lortab, Acetaminophen, Fioricet, Paracetamol, Darvocet-N 100, Excedrin, Tylenol PM, NyQuil, Ultracet, Tylenol with Codeine, Acetaminophen/Hydrocodone, Tylenol with Codeine 3, Lorcet 10/650, Panadol, Coricidin, Vicodin ES, Excedrin Migraine

FDA Medwatch Alert: Acetaminophen: Drug Safety Communication - Association with Risk of Serious Skin Reactions

Posted 1 Aug 2013 by Drugs.com

ISSUE: FDA notified healthcare professionals and patients that acetaminophen has been associated with a risk of rare but serious skin reactions. Acetaminophen is a common active ingredient to treat pain and reduce fever; it is included in many prescription and over-the-counter (OTC) products.  These skin reactions, known as Stevens-Johnson Syndrome (SJS), toxic epidermal necrolysis (TEN), and acute generalized exanthematous pustulosis (AGEP), can be fatal. These reactions can occur with first-time use of acetaminophen or at any time while it is being taken.  Other drugs used to treat fever and pain/body aches (e.g., non-steroidal anti-inflammatory drugs, or NSAIDS, such as ibuprofen and naproxen) also carry the risk of causing serious skin reactions, which is already described in the warnings section of their drug labels. BACKGROUND: This new information resulted from the Agency’s rev ... Read more

Related support groups: Vicodin, Norco, Tylenol, Lortab, Acetaminophen, Fioricet, Paracetamol, Darvocet-N 100, Excedrin, Tylenol PM, NyQuil, Ultracet, Tylenol with Codeine, Acetaminophen/Hydrocodone, Tylenol with Codeine 3, Lorcet 10/650, Panadol, Coricidin, Vicodin ES, Excedrin Migraine

Tylenol-Induced Liver Failure Presents Own Set of Problems: Study

Posted 19 Jul 2013 by Drugs.com

WEDNESDAY, July 17 – People with liver failure caused by an overdose of acetaminophen (Tylenol) have poorer health than patients whose liver failure was caused by other problems, a new study finds. They reported more days of poor mental and physical health, activity limitations because of poor health, pain, anxiety and depression than other liver failure patients, U.S. researchers found. Acetaminophen-overdose patients also had higher rates of substance abuse and psychiatric disease than other liver failure patients, the study found. And patients who suffered an accidental acetaminophen overdose were less likely to have psychiatric disorders than those who intentionally overdosed, 48 percent versus 82 percent. For the study, published online in the journal Liver Transplantation, the researchers analyzed data from more than 280 patients who were diagnosed with acute liver failure ... Read more

Related support groups: Vicodin, Norco, Tylenol, Lortab, Acetaminophen, Fioricet, Paracetamol, Darvocet-N 100, Excedrin, Tylenol PM, NyQuil, Ultracet, Tylenol with Codeine, Acetaminophen/Hydrocodone, Tylenol with Codeine 3, Lorcet 10/650, Panadol, Coricidin, Vicodin ES, Excedrin Migraine

Know What's in Your Child's Medications, FDA Warns

Posted 17 Mar 2013 by Drugs.com

SUNDAY, March 17 – It's the time of year when cold season and allergy season overlap, and parents need to know the active ingredients in the medicines they give their children for these conditions, the U.S. Food and Drug Administration warns. Taking more than one medicine at a time could cause serious health problems if the drugs have the same active ingredient, which is the component that makes the medicine effective against a particular condition. For over-the-counter products, active ingredients are listed first on a medicine's Drug Facts label. For prescription medicines, active ingredients are listed in a patient package insert or consumer information sheet provided by the pharmacist, the FDA said. Many medicines have just one active ingredient. But combination medicines – such as those for allergy, cough or fever and congestion – may have more than one. Antihistamine is an ... Read more

Related support groups: Vicodin, Norco, Tylenol, Lortab, Acetaminophen, Ibuprofen, Benadryl, Advil, Zyrtec, Sta-D, Claritin, Fioricet, Allegra, Loratadine, Diphenhydramine, Pseudoephedrine, Paracetamol, Darvocet-N 100, Motrin, Sudafed

Doubling Up on Cold, Flu Remedies May Harm Liver

Posted 30 Jan 2013 by Drugs.com

WEDNESDAY, Jan. 30 – Taking too much acetaminophen, an active ingredient in many commonly used drugs for fever and pain relief, including Tylenol, can cause liver damage, experts at the U.S. Food and Drug Administration warn. People suffering from a cold or the flu may be tempted to take a combination of medicines to treat several symptoms. Used correctly, acetaminophen can be safe and effective. More than 600 prescription and over-the-counter medications contain acetaminophen, however, and doubling up on these remedies can be dangerous, the FDA cautioned. Complicating matters, signs of an acetaminophen overdose may not become apparent for days. "If you're taking more than one medicine at a time, you may be putting yourself at risk for liver damage," Dr. Fathia Gibril, a supervisory medical officer at the FDA, said in an agency news release. Over-the-counter medications are used by 70 ... Read more

Related support groups: Vicodin, Norco, Tylenol, Lortab, Acetaminophen, Fioricet, Paracetamol, Darvocet-N 100, Excedrin, Cold Symptoms, Tylenol PM, NyQuil, Ultracet, Tylenol with Codeine, Acetaminophen/Hydrocodone, Tylenol with Codeine 3, Lorcet 10/650, Panadol, Coricidin, Vicodin ES

Tylenol Overdose Can Be Deadly for a Child

Posted 10 Jun 2012 by Drugs.com

FRIDAY, June 8 – Overdoses of the pain and fever drug acetaminophen (brand name Tylenol) are a leading cause of acute liver failure in children, and more public education is needed to warn parents and others of this danger, experts say. Acetaminophen is a widely available over-the-counter medication, but repeated doses above the recommended level, or overdoses due to errors or intentional consumption, can lead to acute liver failure and even death in children, according to Dr. Rod Lim, of the Children's Hospital at the London Health Sciences Center in Ontario, Canada, and colleagues. Writing in the June 4 issue of the Canadian Medical Association Journal, they cite a case study of parents who mistakenly gave their 22-day-old baby boy too much acetaminophen after a circumcision. The mistake was discovered, and the child recovered after receiving intravenous treatment with ... Read more

Related support groups: Percocet, Vicodin, Norco, Tylenol, Lortab, Acetaminophen, Fioricet, Paracetamol, Darvocet-N 100, Endocet, Excedrin, Tylenol PM, NyQuil, Ultracet, Tylenol with Codeine, Acetaminophen/Hydrocodone, Roxicet, Percocet 10/325, Tylenol with Codeine 3, Lorcet 10/650

Many Americans Taking Too Much Acetaminophen

Posted 2 Jun 2012 by Drugs.com

FRIDAY, June 1 – Many U.S. adults are at risk for overdosing on over-the-counter pain relievers containing acetaminophen, according to a new study. Acetaminophen (Tylenol) is the most commonly used over-the-counter pain medication in the United States, and acetaminophen overdose is the leading cause of acute liver failure, according to researchers from Northwestern University in Evanston, Ill.. The researchers interviewed 500 adult patients at outpatient general medicine clinics in Atlanta and Chicago. More than half had used acetaminophen in the past six months and 19 percent said they were heavy users, which means they took acetaminophen every day or a couple of times a week. The study authors then assessed whether the patients understood the recommended dosage of acetaminophen products and if they were able to take them safely. The results showed that nearly a quarter of the ... Read more

Related support groups: Percocet, Vicodin, Norco, Tylenol, Lortab, Acetaminophen, Fioricet, Paracetamol, Darvocet-N 100, Endocet, Excedrin, Tylenol PM, NyQuil, Ultracet, Tylenol with Codeine, Acetaminophen/Hydrocodone, Roxicet, Percocet 10/325, Tylenol with Codeine 3, Lorcet 10/650

Patients May Receive Too Much Acetaminophen in Hospital

Posted 23 May 2012 by Drugs.com

WEDNESDAY, May 23 – Roughly 2.5 percent of admitted hospital patients may receive more than the safe daily cumulative dose of the pain-reliever acetaminophen, best known as Tylenol, on at least one day, according to a new U.S. study. Patients on more than one drug containing acetaminophen often consume more than the recommended 4 grams per day of the drug, the researchers from Thomas Jefferson University Hospital in Philadelphia found. Together, two tablets of extra-strength Tylenol contain 1 gram of acetaminophen, commonly used to relieve pain and reduce fever. Over the course of two years, researchers led by Dr. Jesse Civan examined 46,000 hospital admissions and the medications those patients were given. They found that on at least one day of hospitalization, roughly 1,100 patients received more than 4 grams of acetaminophen in the form of Tylenol, Percocet and similar drugs. The ... Read more

Related support groups: Percocet, Vicodin, Norco, Tylenol, Lortab, Acetaminophen, Fioricet, Paracetamol, Darvocet-N 100, Endocet, Excedrin, Tylenol PM, NyQuil, Ultracet, Tylenol with Codeine, Acetaminophen/Hydrocodone, Roxicet, Percocet 10/325, Tylenol with Codeine 3, Lorcet 10/650

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