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Weight Gain From Antidepressants Is Minimal, Study Suggests

Posted 5 Jun 2014 by Drugs.com

THURSDAY, June 5, 2014 – While it has long been known that some antidepressants can help spur weight gain, a new study finds that the actual amount gained is usually small. "This study was motivated in the first place by the number of patients who have asked me if their medicine is going to make them gain weight," said study co-author Dr. Roy Perlis, director of Massachusetts General Hospital's Center for Experimental Drugs and Diagnostics, in Boston. "It's the most common question I get when prescribing any medication, frankly," he said. "But most antidepressant studies have been short term, looking at just a few months of treatment. So I wanted to look at it for a longer period of time," Perlis explained. "I think our findings should be reassuring to patients. Yes, antidepressants can lead in some cases to small amounts of weight gain, that's true. And we need to pay attention to it, ... Read more

Related support groups: Depression, Lexapro, Zoloft, Cymbalta, Wellbutrin, Effexor, Prozac, Celexa, Paxil, Citalopram, Amitriptyline, Sertraline, Effexor XR, Bupropion, Fluoxetine, Venlafaxine, Wellbutrin XL, Mirtazapine, Remeron, Elavil

FDA Approves First Generic Versions of Antidepressant Drug Cymbalta

Posted 11 Dec 2013 by Drugs.com

December 11, 2013 – The U.S. Food and Drug Administration today approved the first generic versions of Cymbalta (duloxetine delayed-release capsules), a prescription medicine used to treat depression and other conditions. Aurobindo Pharma Ltd., Dr. Reddy’s Laboratories Ltd., Lupin Ltd., Sun Pharma Global FZE, Teva Pharmaceuticals USA, and Torrent Pharmaceuticals Ltd. have received FDA approval to market duloxetine in various strengths. “Health care professionals and consumers can be assured that these FDA-approved generic drugs have met our rigorous standards,” said Kathleen Uhl, M.D., acting director of the Office of Generic Drugs in the FDA’s Center for Drug Evaluation and Research. “Generic drugs offer greater access to health care for many people.” Depression is characterized by symptoms that interfere with a person's ability to work, sleep, study, eat, and enjoy once-pleasu ... Read more

Related support groups: Depression, Cymbalta, Duloxetine

Generic Cymbalta Approved

Posted 11 Dec 2013 by Drugs.com

WEDNESDAY, Dec. 11, 2013 – The first generic versions of the antidepressant drug Cymbalta (duloxetine delayed-release capsules) have been approved by the U.S. Food and Drug Administration. License to produce generic Cymbalta was granted to Aurobindo Pharma Ltd., Dr. Reddy's Laboratories Ltd., Lupin Ltd., Sun Pharma Global FZE, Teva Pharmaceuticals USA, and Torrent Pharmaceuticals Ltd., the agency said Wednesday in a news release. Duloxetine is prescribed to treat symptoms of depression, which may include: depressed mood, loss of interest in usual activities, changes in weight or appetite, sleep problems, feelings of guilt or worthlessness, inability to concentrate or suicidal thoughts, the FDA said. Labeling on duloxetine and other antidepressants says these drugs could increase users' risks of suicidal thinking and behavior, particularly among children, teens and young adults. Users ... Read more

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7 out of 10 Americans Take a Prescription Drug: Study

Posted 27 Jun 2013 by Drugs.com

THURSDAY, June 27 – Nearly 70 percent of Americans take prescription drugs, with antibiotics, antidepressants and painkillers being the most widely used, according to a new study. Researchers also found that more than half of patients take two prescription drugs, while 20 percent take five or more prescription medications. One other key finding: "As you get older you tend to get more prescriptions, and women tend to get more prescriptions than men," study author Dr. Jennifer St. Sauver, of the Mayo Clinic Center for the Science of Health Care Delivery, said in a Mayo news release. The findings come from an analysis of 2009 statistics from people living in Olmsted County, Minn., near the Mayo Clinic. St. Sauver believes the findings are comparable to people living elsewhere in the United States. According to the study, 17 percent of patients took antibiotics, 13 percent took ... Read more

Related support groups: Suboxone, Oxycodone, Methadone, Lexapro, Zoloft, Cymbalta, Hydrocodone, OxyContin, Vicodin, Effexor, Prozac, Morphine, Celexa, Norco, Fentanyl, Lortab, Paxil, Codeine, Citalopram, Opana

Antidepressant Lessens Chemo-Related Pain

Posted 2 Apr 2013 by Drugs.com

TUESDAY, April 2 – The antidepressant drug Cymbalta can help relieve chronic pain caused by certain cancer drugs, a new clinical trial reports. The study, appearing in the April 3 issue of the Journal of the American Medical Association, tested Cymbalta on patients with chronic cases of chemotherapy-related peripheral neuropathy – pain, tingling and numbness in the limbs that arises when certain chemo drugs damage the nerves. Of 115 patients who took the antidepressant for five weeks, 59 percent got some degree of pain relief, compared with 38 percent of patients given a drug-free placebo. Researchers said the findings support what some doctors have seen in everyday practice, since Cymbalta is already used to treat the chemo side effect. That use has been based on the fact that Cymbalta helps with other types of pain, said Dr. Michael Stubblefield, who was not involved in the study ... Read more

Related support groups: Pain, Cymbalta, Duloxetine

Psychiatric Drugs More Often Prescribed in the South

Posted 1 Feb 2013 by Drugs.com

FRIDAY, Feb. 1 – Use of psychiatric medications is most prevalent in the southern United States and least prevalent in the West, according to a new U.S. study. Although people living in the West are the least likely to use antipsychotics, antidepressants and stimulants, the Yale researchers found that the drugs' use is 40 percent higher in a large section of the South than in other parts of the country. The study authors attributed this discrepancy to variations in local access to health care and marketing efforts within the pharmaceutical industry. "The geographic patterns we identify are striking and map onto the patterns found for a host of other medical conditions and treatments, from cognitive decline to bypass surgery," Marissa King, assistant professor of organizational behavior at the Yale School of Management, said in a school news release. "Our work suggests that access to ... Read more

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Antidepressant Cymbalta Might Ease Chemo-Linked Pain

Posted 4 Jun 2012 by Drugs.com

MONDAY, June 4 – Cancer patients on certain chemotherapies often experience a painful tingling in their extremities called peripheral neuropathy, and a new study suggests the antidepressant Cymbalta may be the first treatment to work against the condition. In the small study, 59 percent of patients who'd experienced peripheral neuropathy said that they gained relief after taking Cymbalta (duloxetine), compared to 39 percent who took a "dummy" pill. Taking Cymbalta daily "decreases chronic chemotherapy-induced neuropathy and pain severity in the majority of patients who take it and it improves function and quality of life," said study author Ellen Lavoie Smith, an assistant professor at the University of Michigan's School of Nursing. She said the drug is also "very well tolerated" by most patients. Smith spoke at a news briefing Sunday at the annual meeting of the American Society of ... Read more

Related support groups: Cymbalta, Cancer, Peripheral Neuropathy, Duloxetine, Taxol, Paclitaxel, Onxol

Newer Antidepressants May Be Safe for Parkinson's Patients

Posted 11 Apr 2012 by Drugs.com

WEDNESDAY, April 11 – Some of the newer antidepressants can help treat depression in people with Parkinson's disease without aggravating other disease symptoms such as tremor or rigidity, researchers have found. Nearly 1 million people in the United States are living with Parkinson's disease, a progressive movement disorder marked by tremor, slowness and/or rigidity. Parkinson's disease and depression tend to travel together, and there has been concern that some of the medications used to treat depression may worsen motor symptoms. A new study published online April 11 and in the April 17 print issue of Neurology shows that this is not the case, at least when it comes to the antidepressants Paxil (paroxetine) and Effexor (venlafaxine). Paxil is in the class of drugs known as SSRIs (selective serotonin reuptake inhibitors) while Effexor is an SNRI (serotonin and norepinephrine reuptake ... Read more

Related support groups: Depression, Lexapro, Zoloft, Cymbalta, Effexor, Prozac, Celexa, Paxil, Citalopram, Pristiq, Sertraline, Effexor XR, Fluoxetine, Venlafaxine, Savella, Parkinson's Disease, Escitalopram, Paroxetine, Luvox, Duloxetine

Minorities, Medicare Recipients Less Likely to Get Antidepressants

Posted 9 Apr 2012 by Drugs.com

MONDAY, April 9 – Hispanics and blacks are less likely to be prescribed antidepressants than whites, and Medicare and Medicaid patients are less likely to receive the drugs than those with private insurance, a new study says. University of Michigan School of Public Health researchers examined data from 1993 to 2007 and found that whites were 1.5 times more likely to receive antidepressants than blacks or Hispanics with major depression. The study also found that Medicare and Medicaid patients were 31 percent and 38 percent less likely to be prescribed antidepressants than privately insured patients. Race didn't play a role in the type of antidepressants prescribed to patients, but insurance did. Medicare and Medicaid patients were 58 percent and 61 percent less likely to receive newer antidepressants than privately insured patients. Newer types of antidepressants such as serotonin ... Read more

Related support groups: Depression, Lexapro, Zoloft, Cymbalta, Wellbutrin, Effexor, Prozac, Celexa, Paxil, Trazodone, Citalopram, Pristiq, Viibryd, Amitriptyline, Sertraline, Effexor XR, Bupropion, Fluoxetine, Venlafaxine, Savella

Best Antidepressant May Depend on Patient: Study

Posted 5 Dec 2011 by Drugs.com

TBD – Newer antidepressants seem to be about as effective as one another, a new analysis indicates. This suggests that the choice of which drug is appropriate for which patient should be made on the basis of such considerations as side effects, cost and patient preference. "They're all equally effective," said Dr. David Schlager, a clinical assistant professor of psychiatry and behavioral science at Texas A&M Health Science Center College of Medicine. "They're interchangeable except for side effects," he added, so psychiatrists do tend to "exploit the side-effect profile" to find suitable medications for individual patients, he added. According to the background information in the new study, appearing in the Dec. 6 issue of Annals of Internal Medicine, some 27 million people in the United States had taken antidepressants as of 2005. Most of these drugs are "second-generation" ... Read more

Related support groups: Lexapro, Zoloft, Cymbalta, Wellbutrin, Effexor, Prozac, Celexa, Paxil, Citalopram, Pristiq, Sertraline, Effexor XR, Bupropion, Fluoxetine, Venlafaxine, Savella, Wellbutrin XL, Wellbutrin SR, Escitalopram, Paroxetine

Fear of Antidepressants Keep Many From Disclosing Depression

Posted 13 Sep 2011 by Drugs.com

TUESDAY, Sept. 13 – For a nation that seems ready to pop a pill for any ill, a new study suggests that the opposite seems true for some people with symptoms of depression, whose concerns about the side effects of antidepressants were the top reason they wouldn't disclose warning signs to their doctors. A phone survey of more than 1,000 adults who had previously participated in the California Behavioral Risk Factor Survey System, which probed depression-related beliefs, showed that 43 percent reported one or more reasons for not talking to their primary care physician about their depression. Nearly a quarter of them worried that their doctor would recommend antidepressants – the most frequently cited reason for withholding the information. Other stated barriers to sharing depressive symptoms included the belief that it's not a primary care physician's job to deal with emotional issues ... Read more

Related support groups: Depression, Lexapro, Zoloft, Cymbalta, Wellbutrin, Effexor, Prozac, Celexa, Paxil, Trazodone, Citalopram, Pristiq, Viibryd, Amitriptyline, Sertraline, Effexor XR, Bupropion, Fluoxetine, Venlafaxine, Savella

Certain Antidepressants Linked to Falls in Nursing Homes

Posted 26 Jul 2011 by Drugs.com

TUESDAY, July 26 – In the days after they start taking non-SSRI (selective serotonin reuptake inhibitor) antidepressants, such as bupropion or venlafaxine, nursing home residents are at significantly greater risk for falls, according to a new study. Researchers found the increased risk for falls also applies to those who had a dosage increase of their current prescription. "Our results identify the days following a new prescription or increased dose of a non-SSRI antidepressant as a window of time associated with a particularly high risk of falling among nursing home residents," said study author Dr. Sarah D. Berry, a scientist at the Institute for Aging Research of Hebrew SeniorLife in Boston. More closely monitoring these nursing home residents for two days after a change in these antidepressants could help prevent falls, the researchers said. In conducting the study, recently ... Read more

Related support groups: Depression, Lexapro, Zoloft, Cymbalta, Wellbutrin, Effexor, Prozac, Celexa, Paxil, Citalopram, Pristiq, Sertraline, Effexor XR, Bupropion, Fluoxetine, Venlafaxine, Savella, Wellbutrin XL, Wellbutrin SR, Escitalopram

Antidepressant Use Rising as Psychotherapy Rates Fall

Posted 6 Dec 2010 by Drugs.com

MONDAY, Dec. 6 – Even as fewer Americans have sought psychotherapy for their depression, antidepressant prescription rates have continued to climb in recent years, a new survey reveals. "This is an encouraging trend as it suggests that fewer depressed Americans are going without treatment," said study author Dr. Mark Olfson, a professor of clinical psychiatry at Columbia University/New York State Psychiatric Institute in New York City. "At the same time, however, the decline in psychotherapy raises the possibility that many depressed patients are not receiving optimal care." "While progress is being made in increasing the availability of depression care, a mismatch is opening up between clinical evidence and practice," Olfson cautioned. "For many depressed adults and youth, a combination of psychotherapy and antidepressants is the most effective approach. Yet, only about one-third of ... Read more

Related support groups: Depression, Lexapro, Zoloft, Cymbalta, Wellbutrin, Effexor, Prozac, Celexa, Paxil, Trazodone, Citalopram, Pristiq, Amitriptyline, Sertraline, Effexor XR, Bupropion, Fluoxetine, Venlafaxine, Savella, Wellbutrin XL

FDA Clears Cymbalta to Treat Chronic Musculoskeletal Pain

Posted 5 Nov 2010 by Drugs.com

Indications include osteoarthritis, chronic lower back pain ROCKVILLE, Md., Nov. 4, 2010--The U.S. Food and Drug Administration today approved Cymbalta (duloxetine hydrochloride) to treat chronic musculoskeletal pain, including discomfort from osteoarthritis and chronic lower back pain. Cymbalta was first used to treat major depressive disorder in 2004.  “Up to three quarters of the population experience chronic pain at some time in their lives," said Janet Woodcock, M.D., director of FDA’s Center for Drug Evaluation and Research. “This approval means that many of those people now have another treatment option.” Since its initial approval, about 30 million patients in the United States have used Cymbalta. It was approved for the treatment of diabetic peripheral neuropathy in 2004; generalized anxiety disorder and maintenance treatment of major depression in 2007; and fibromyalgia in 2008 ... Read more

Related support groups: Pain, Back Pain, Cymbalta, Osteoarthritis, Duloxetine

Antidepressant Use in U.S. Has Almost Doubled

Posted 16 Dec 2009 by Drugs.com

MONDAY, Aug. 3 – Antidepressant use among United States residents almost doubled between 1996 and 2005, along with a concurrent rise in the use of other psychotropic medications, a new report shows. The increase seemed to span virtually all demographic groups. "Over 10 percent of people over the age of 6 were receiving anti-depression medication. That strikes me as significant," said study author Dr. Mark Olfson, a professor of clinical psychiatry at Columbia University/New York State Psychiatric Institute in New York City. According to background information in the study, antidepressants are now the most widely prescribed class of drugs in the United States. The expansion in use dates back to the 1980s, with the introduction of the antidepressant Prozac (fluoxetine). The study found that 5.84 percent of U.S. residents aged 6 and over were using antidepressants in 1996, compared with ... Read more

Related support groups: Depression, Lexapro, Zoloft, Cymbalta, Wellbutrin, Effexor, Prozac, Celexa, Paxil, Trazodone, Citalopram, Pristiq, Amitriptyline, Sertraline, Effexor XR, Bupropion, Fluoxetine, Venlafaxine, Savella, Wellbutrin XL

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