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Related terms: B-cell Lymphoma, Burkitt's Lymphoma, Burkitt's Tumor, Cancer, Burkitt Lymphoma, High-grade B-cell Lymphoma, Lymphoma, Burkitt, Small non-cleaved cell Lymphoma

Study Finds Big Strides Made in Treating Leukemia, Lymphoma in Past Decade

Posted 24 Nov 2010 by Drugs.com

WEDNESDAY, Nov. 24 – Clinicians have made remarkable advances in treating blood cancers with bone marrow and blood stem cell transplants in recent years, significantly reducing the risk of treatment-related complications and death, a new study shows. Between the early 1990s and 2007, there was a 41 percent drop in the overall risk of death in an analysis of more than 2,500 patients treated at Fred Hutchinson Cancer Center in Seattle, a leader in the field of blood cancers and other malignancies. Researchers from the Fred Hutchinson Cancer Center, who conducted the study, also noted dramatic decreases in treatment complications such as infection and organ damage. The study was published in the Nov. 24 issue of the New England Journal of Medicine "We have made enormous strides in understanding this very complex procedure and have yielded quite spectacular results," said study senior ... Read more

Related support groups: Hairy Cell Leukemia, Leukemia, Chronic Myelogenous Leukemia (CML), Lymphoma, Chronic Lymphocytic Leukemia (CLL), Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Cutaneous T-cell Lymphoma, Non-Hodgkin's Lymphoma, Hodgkin's Lymphoma, Acute Lymphocytic Leukemia, Acute Promyelocytic Leukemia, Follicular Lymphoma, Acute Nonlymphocytic Leukemia, Infection Prophylaxis, Chronic Lymphocytic Leukemia

Cancer Drug Seems to Work by Activating Virus

Posted 25 Apr 2010 by Drugs.com

FRIDAY, April 23 – The cancer drug cyclophosphamide activates a viral infection that helps anti-viral medications eliminate a virus-linked cancer, says a new study. The drug is used to treat Burkitt lymphoma, an aggressive, fast-growing type of non-Hodgkin lymphoma that often occurs in children. In Africa, the cancer is caused by the Epstein-Barr virus (EBV), which typically remains dormant inside tumor cells. This study of 21 patients, ages 5 to 15, who were being treated with cyclophosphamide, found that the drug triggers an active EBV infection. Increased replication of the virus in cancer cells makes the cells more susceptible to antiviral drugs, which kill cells containing the replicating virus. The study was published in the April issue of the journal Clinical Cancer Research. "What we have learned from this work is a potential means of capitalizing on presence of viral genomes ... Read more

Related support groups: Cytoxan, Cyclophosphamide, Neosar, Cytoxan Lyophilized, Burkitt Lymphoma

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