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Pacira Pharmaceuticals, Inc. Announces U.S. FDA Approval of Exparel For Postsurgical Pain Management
Posted 31 Oct 2011 by Drugs.com
PARSIPPANY, N.J., Oct. 31, 2011 /PRNewswire via COMTEX/ – Pacira Pharmaceuticals, Inc. announces that the U.S. Food and Drug Administration (FDA) has approved Exparel (bupivacaine liposome injectable suspension) 1.3% for administration into the surgical site to produce postsurgical analgesia. In a pivotal hemorrhoidectomy trial of Exparel compared to placebo, where all patients with inadequate pain control received opioids for rescue pain relief, Exparel demonstrated significant reductions in cumulative pain scores with an attendant decrease in opioid consumption for up to 72 hours. "As a non-opioid local analgesic, Exparel represents an evolution in the management of postsurgical pain by providing analgesia for several days with a single intraoperative infiltration," said Dave Stack, president and CEO of Pacira Pharmaceuticals, Inc. "This FDA approval is an important milestone for ... Read more
Related support groups: Pain, Postoperative Pain, Bupivacaine
Hypnosis Plus Local Anesthesia Might Work Well for Some Surgeries
Posted 14 Jun 2011 by Drugs.com
TUESDAY, June 14 – Certain surgeries that typically require the use of general anesthesia could be safely performed with localized anesthesia in combination with hypnosis, Belgian researchers suggest. The finding stems from a pair of very small case-control studies that explored the combo's potential during surgical procedures performed for breast cancer patients and thyroid patients, respectively. The studies revealed that, relative to general anesthesia, the local anesthesia/hypnosis approach sped up the healing process, reduced the need for post-surgery opioid drugs and reduced hospitalization time. "There is still a lot of debate around the exact mechanism that allows hypnosis to reduce pain perception," said study author and professor Fabienne Roelants in a European Anaesthesiology Congress news release, "but what is absolutely clear is that it does so." She and her colleague ... Read more
Related support groups: Surgery, Lidocaine, Xylocaine, Marcaine, Procaine, Septocaine, Bupivacaine, Novocain, Prilocaine, Tetracaine, Marcaine HCl, Marcaine Spinal, Carbocaine, Naropin, Sensorcaine
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Related Condition Support Groups
Local Anesthesia, Cesarean Section, Postoperative Pain
Related Drug Support Groups
Marcaine, Marcaine HCl, Marcaine Spinal, Sensorcaine, Sensorcaine-MPF, Sensorcaine-MPF Spinal