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Botox Offers Little Relief for Migraine, Study Finds
Posted 24 Apr 2012 by Drugs.com
TUESDAY, April 24 – Botox is considered a preventive medication for debilitating migraine headaches, but a new review finds that it may only help people with chronic migraines or chronic daily headaches. And, even then, the effect appears to only be "small to modest." The review found that Botox (botulinum toxin A) was no help for people with episodic migraines (fewer than 15 a month) or chronic tension-type headaches. "Our analyses suggest that botulinum toxin A may be associated with improvement in the frequency of chronic migraine and chronic daily headaches, but not with improvement in the frequency of episodic migraine, chronic tension-type headaches or episodic tension-type headaches. However, the association of botulinum toxin A with clinical benefit was small," wrote the authors of the review. Still, the review's lead author, Dr. Jeffrey Jackson, said, "If I was having more ... Read more
Related support groups: Headache, Migraine, Botox, New Daily Persistent Headache, Botox Cosmetic, Onabotulinumtoxina
Drugs to Make You Look Beautiful -- But at What Price?
Posted 4 Nov 2011 by Drugs.com
FRIDAY, Nov. 4 – Skimpy eyelashes, balding pates and wrinkles aren't diseases, but they may as well be in a society that "medicalizes" normal conditions by producing drugs not to cure or heal, but to enhance, some health experts contend. So the news that a cosmetic company is developing a pill to prevent hair from graying will offer Americans more options than ever to not only turn back the clock, but – as experts note – to eliminate common differences that make individuals distinct. The booming worldwide "lifestyle" drug market – which was estimated to surpass $29 billion in 2007 – pits problems of a social or cosmetic nature against conditions threatening physical health or well-being. But all drugs in the United States must undergo the same rigorous approval process whether they are designated for disease prevention or treatment or to alter people's looks or behavior. This ... Read more
Related support groups: Botox, Finasteride, Propecia, Proscar, Latisse, Botox Cosmetic, Onabotulinumtoxina
Anti-Wrinkle Gel Might Work Like Botox Without Needles
Posted 21 Sep 2011 by Drugs.com
TUESDAY, Sept. 20 – Preliminary industry-funded research suggests that a gel based on the active ingredient of the injectable Botox wrinkle treatment could help reduce the lines around the eyes known as crow's feet – without the pain of needles. The effects of the gel, which uses botulinum toxin, last for about four months, comparable to that produced by Botox injections, the researchers said. The new study is encouraging since it showed that the gel "noticeably softened crow's feet," said study author Dr. Michael Kane, a plastic surgeon at the Manhattan Eye, Ear and Throat Hospital in New York City. He has served as an investigator and consultant to Revance Therapeutics of Mountain View, Calif., the gel maker that has been trying to develop a Botox alternative for several years. There are several caveats, he pointed out. It's not clear how much the treatment would cost, whether it ... Read more
Related support groups: Botox, Facial Wrinkles, Dysport, Botox Cosmetic
Accidental Medication Poisonings in Kids on the Rise
Posted 16 Sep 2011 by Drugs.com
FRIDAY, Sept. 16 – Despite ongoing prevention efforts, a growing number of young children are being accidentally poisoned with medications, according to new research. The study, which was based on data reported to the American Association of Poison Control Centers between 2001 and 2008, found that medication poisoning among children aged 5 and under increased by 22 percent, although the number of children in the United States in this age group rose by only 8 percent during the study period. "The problem of pediatric poisoning in the U.S. is getting worse, not better," Dr. Randall Bond, of Cincinnati Children's Hospital Medical Center, said in a hospital news release. In conducting the study, which is scheduled for publication in the Journal of Pediatrics, the researchers reviewed information on over 544,000 children who landed in the emergency department due to medication poisoning ... Read more
Related support groups: Suboxone, Xanax, Methadone, Oxycodone, Percocet, OxyContin, Hydrocodone, Vicodin, Morphine, Norco, Fentanyl, Klonopin, Lortab, Lisinopril, Subutex
Botox Approved to Treat Urinary Incontinence
Posted 24 Aug 2011 by Drugs.com
WEDNESDAY, Aug. 24 – Botox (onabotulinumtoxinA) has been approved by the U.S. Food and Drug Administration to treat urinary incontinence in people with neurological conditions such as spinal cord injury and multiple sclerosis. Some people with these conditions have uncontrolled bladder contractions, which leads to inability to retain urine. Common treatments include medication or a catheter, the agency said in a news release. The use of Botox involves injecting the drug into the bladder, relaxing the bladder. The drug's effects last for about nine months, the FDA said. Botox was evaluated for this use in clinical studies involving 691 people. The most common adverse reactions included urinary tract infection and urinary retention. Botox also is FDA-approved for reducing facial frown lines, and treating chronic migraine, certain forms of muscle stiffness, severe underarm sweating and ... Read more
Related support groups: Urinary Incontinence, Botox
FDA Approves Botox to Treat Specific Form of Urinary Incontinence
Posted 24 Aug 2011 by Drugs.com
SILVER SPRING, Md., Aug. 24, 2011 /PRNewswire-USNewswire/ – The U.S. Food and Drug Administration today approved Botox (onabotulinumtoxinA) injection to treat urinary incontinence in people with neurologic conditions such as spinal cord injury and multiple sclerosis who have overactivity of the bladder. Uninhibited urinary bladder contractions in people with some neurological conditions can lead to an inability to store urine. Current management of this condition includes medications to relax the bladder and use of a catheter to regularly empty the bladder. The treatment consists of Botox being injected into the bladder resulting in relaxation of the bladder, an increase in its storage capacity and a decrease in urinary incontinence. "Urinary incontinence associated with neurologic conditions can be difficult to manage," said George Benson, deputy director, Division of Reproductive and ... Read more
Related support groups: Urinary Incontinence, Botox, Onabotulinumtoxina
Study Finds Botox Alternative Better at Smoothing 'Crow's Feet'
Posted 20 Jun 2011 by Drugs.com
MONDAY, June 20 – A more recently approved version of botulinum toxin type A beat the anti-wrinkle medication Botox in a trial that compared the respective powers of each in erasing those unwanted lines of aging around the eyes known as "crow's feet." "One month after treatment, on a two-to-one preference basis, patients picked Dysport over the Botox in terms of wrinkle improvement," said study co-author Dr. Corey S. Maas, an associate clinical professor at the University of California, San Francisco, as well as a plastic surgeon with The Maas Clinic, based in San Francisco and Lake Tahoe. "So, we can say that when it comes to addressing the smile lines around the eyes, the crow's feet, at one month the Dysport is more effective than Botox," Maas said. "And that's a big deal, because Botox is such a recognized household name now. And it's such a great drug. But when you have something ... Read more
Related support groups: Botox, Facial Wrinkles, Dysport, Botox Cosmetic, Onabotulinumtoxina, Abobotulinumtoxina
FDA Approves Botox to Treat Chronic Migraine
Posted 17 Oct 2010 by Drugs.com
SILVER SPRING, Md., Oct. 15 – The U.S. Food and Drug Administration today approved Botox injection (onabotulinumtoxinA) to prevent headaches in adult patients with chronic migraine. Chronic migraine is defined as having a history of migraine and experiencing a headache on most days of the month. "Chronic migraine is one of the most disabling forms of headache," said Russell Katz, M.D., director of the Division of Neurology Products in the FDA's Center for Drug Evaluation and Research. "Patients with chronic migraine experience a headache more than 14 days of the month. This condition can greatly affect family, work, and social life, so it is important to have a variety of effective treatment options available." Migraine headaches are described as an intense pulsing or throbbing pain in one area of the head. The headaches are often accompanied by nausea, vomiting, and sensitivity to ... Read more
Related support groups: Migraine, Botox, Botox Cosmetic, Onabotulinumtoxina
Injections May Relieve Drooling in Nerve-Damaged Kids
Posted 22 Sep 2010 by Drugs.com
WEDNESDAY, Sept. 22 – Botulinum toxin injections may temporarily relieve drooling in children with certain neurological conditions, a new European study has found. Depending on its severity, drooling can lead to stigmatization and social neglect, numerous daily clothing changes, skin irritation around the mouth, aspiration pneumonia and dehydration, Dr. Arthur Scheffer of Radboud University Medical Center in Nijmegen, the Netherlands, and colleagues noted in a news release about their study. In the study, Scheffer's team gave botulinum toxin injections to 131 children, average age 10.9 years, with cerebral palsy or other non-progressive neurological conditions, as well as moderate to severe drooling. The injections were confined to the submandibular glands, which are responsible for 70 percent of saliva production while a person is resting. Two months after the injections, the average ... Read more
Related support groups: Botox, Botox Cosmetic, Onabotulinumtoxina
Botox Injections May Relieve Tennis Elbow Pain
Posted 26 Apr 2010 by Drugs.com
MONDAY, April 26 – Botulinum toxin, which smoothes facial wrinkles through injections of the drug Botox, can also help people who suffer from "tennis elbow," a new study finds. But the researchers warn that it must be injected carefully, and there's a potentially nettlesome side effect, according to the report published online April 26 in the Canadian Medical Association Journal. Researchers at the Imam Khomeini Hospital Complex at Tehran University in Iran gave botulinum toxin injections to 48 patients with tennis elbow who hadn't been helped by previous treatments. Tennis elbow, which causes pain and inflammation in the upper arm near the elbow, affects some people who repeatedly move their wrists or forearms while taking part in activities like tennis. The researchers customized the injection sites based on the length of each patient's forearm instead of giving injections at the ... Read more
Related support groups: Botox, Epicondylitis - Tennis Elbow
Botox (onabotulinumtoxinA) Receives FDA Approval for Treatment of Upper Limb Spasticity in Adults
Posted 10 Mar 2010 by Drugs.com
IRVINE, Calif.--(BUSINESS WIRE)--Mar 10, 2010 - Allergan, Inc. today announced that the United States Food and Drug Administration (FDA) has approved Botox (onabotulinumtoxinA) for the treatment of increased muscle stiffness in the elbow, wrist and fingers in adults with upper limb spasticity. Spasticity is a debilitating condition impacting approximately 1 million Americans1, many of whom suffer from spasticity in the upper limbs following a stroke. Upper limb spasticity may also occur following a spinal cord or traumatic brain injury or in patients affected by multiple sclerosis or adults with a history of cerebral palsy. Although not a life-threatening condition, upper limb spasticity can be severely debilitating and painful, producing disfiguring muscle contractions that can result in stiff, tight muscles in the elbow, wrist and fingers, or a clenched fist. This stiffness hinders a ... Read more
Related support groups: Botox, Chronic Spasticity, Botulinum Toxin Type A
Botox May Prevent Some Migraines
Posted 15 Feb 2010 by Drugs.com
MONDAY, Feb. 15 – Botulinum toxin type A (Botox), the drug that can temporarily erase wrinkles, may also help prevent some types of migraines, a small study suggests. Specifically, Botox may help reduce the recurrence of those migraines people describe as crushing or eye-popping, otherwise known as ocular migraines. However, the treatment does not appear to work for migraines that are experienced as pressure inside the head, the researchers added. "In a previous study, neurologists discovered that most patients with imploding and ocular headaches responded to botulinum toxin A injections with a reduction of their headache frequency, while the majority of patients with exploding type migraines did not respond," said lead researcher Dr. Christine C. Kim, a dermatologist in Encino, Calif. "We tested this hypothesis in a cosmetic dermatology setting, using botulinum toxin A doses that were ... Read more
Related support groups: Migraine, Migraine Prevention, Botox, Migraine Prophylaxis
New Guidelines Suggest Botox for Cerebral Palsy
Posted 25 Jan 2010 by Drugs.com
MONDAY, Jan. 25 – In children and teens with cerebral palsy, botulinum toxin injections can be an effective treatment for spasticity and muscle tightness that interferes with movement, new guidelines from the American Academy of Neurology and the Child Neurology Society state. The guidelines, which stem from a review of available research on drug treatments for cerebral palsy, also said that botulinum toxin type A, nicknamed Botox, is generally safe but does pose some risk. "In reviewing this drug for treatment of spasticity in children, the [U.S.] Food and Drug Administration is investigating isolated cases of generalized weakness following use of botulinum toxin type A for spasticity," Dr. Mauricio R. Delgado, of the University of Texas Southwestern Medical Center in Dallas and lead author of the guidelines, said in a news release from the academy. The guidelines also recommend ... Read more
Related support groups: Botox, Cerebral Palsy
Plastic Surgery Technique Might Ease Migraines
Posted 16 Dec 2009 by Drugs.com
FRIDAY, July 31 – Thanks to a procedure borrowed from cosmetic surgery, Michelle Cramer has now lost most of her frequent and debilitating migraine headaches, as well as her frown lines. Cramer, a graphics illustrator in Williamsburg, Va., suffered about 15 migraines a month for close to a decade until she had surgery to "disarm" various nerves that were apparently controlling her headaches. "I get maybe two migraines a year now," she said. Cramer, 38, participated in a clinical trial to evaluate the surgery, the results of which are published in the August issue of Plastic and Reconstructive Surgery. "The theory here is that there are sites outside the brain in the face and back of the head that can trigger migraines and, if you surgically remove the migraine trigger, the migraine will improve and there's certainly a precedent for the idea," said Dr. Richard Lipton, director of the ... Read more
Related support groups: Migraine, Botox, Botox Cosmetic
FDA Mandates New Warnings for Botox
Posted 30 Apr 2009 by Drugs.com
THURSDAY, April 30 – Reports of deaths among people using popular anti-wrinkle injections such as Botox to treat muscle spasms have prompted a change in labeling. Botox and similar products will now be required to carry boxed warnings, the most serious type of label warning, the U.S. Food and Drug Administration announced Thursday. Most cases involved children given the drug to control muscle spasticity associated with cerebral palsy and adults using it to treat muscle spasticity, migraines and cervical dystonia. "The hospitalizations are very few, deaths are very rare, but they have been reported," said Dr. Ellis F. Unger, acting deputy director of the FDA's Office of Drug Evaluation, said during a teleconference. "We don't want to discourage use of these drugs as patients taking them have significant disability and the drugs are effective to relieve important problems," he said. "But ... Read more
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Overactive Bladder, Migraine Prevention, Migraine Prophylaxis, Chronic Spasticity, Urinary Incontinence, Hyperhidrosis, Cervical Dystonia, Upper Limb Spasticity, Dystonia, Blepharospasm, Strabismus