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Blood Disorders News

Antibiotic May Lower Effect of Some Blood Thinners

Posted 13 days ago by Drugs.com

TUESDAY, July 21, 2015 – The antibiotic dicloxacillin may lessen the effects of some blood-thinning medications, new research shows. "The surprise in the study was just how much of an impact dicloxacillin had," said study author Anton Pottegard, a pharmacist and research fellow at the University of Southern Denmark, in Odense. "Often, the effects in these kinds of studies are quite small. But this was very pronounced: Six out of 10 patients dropped so much in their level of blood-thinning that they were no longer sufficiently protected against clotting and stroke," Pottegard said. Coumadin (warfarin) and similar blood thinners lower the risk of blood clots, a potential cause of strokes and heart attacks, by thinning the blood so blockages don't form in vessels, according to the U.S. National Library of Medicine. Patients with irregular heart rhythms, such as atrial fibrillation, and ... Read more

Related support groups: Infections, Blood Disorders, Warfarin, Coumadin, Metronidazole, Bacterial Infection, Ischemic Stroke, Bactrim, Atrial Fibrillation, Flagyl, Bactrim DS, Prevention of Thromboembolism in Atrial Fibrillation, Polymyxin B, Xifaxan, Septra, Zyvox, Sulfamethoxazole/Trimethoprim, Rifaximin, Ischemic Stroke - Prophylaxis, Bacitracin

Study Sees No Link Between Testosterone Therapy and Blood Clots

Posted 14 days ago by Drugs.com

MONDAY, July 20, 2015 – Testosterone therapy doesn't appear to increase the risk of blood clots in veins, a new study contends. The most common forms of this problem – called venous thromboembolism (VTE) – are deep vein thrombosis (a clot in the leg) and pulmonary embolism (a clot in the lungs). VTE is the third most common type of cardiovascular problem, after heart attack and stroke, the researchers said. There is conflicting information about the link between testosterone therapy and the risk of VTE. As a result, many men with low testosterone and their doctors are reluctant to start testosterone therapy, the study investigators said. "In 2014, the [U.S.] Federal Drug Administration required manufacturers to add a warning about potential risks of VTE to the label of all approved testosterone products," study author Jacques Baillargeon, a professor of epidemiology at the University ... Read more

Related support groups: Blood Disorders, Bleeding Disorder, Testosterone, AndroGel, Testim, Axiron, Androderm, Fortesta, Depo-Testosterone, Testopel, Delatestryl, Testopel Pellets, Striant, AndroGel 1.25 g/actuation, Everone, Testim 5 g/packet, Coagulation Defects and Disorders, Aveed, Testro, Depotest

Blood Test Could Reveal Your Viral History

Posted 4 Jun 2015 by Drugs.com

THURSDAY, June 4, 2015 – A single drop of blood may reveal a range of viruses a person has contracted recently, or possibly years ago, a new study suggests. Writing in the June 5 issue of Science, researchers describe a new technology that can test for more than 1,000 viral strains at the same time – using one drop of blood. Experts said the achievement could represent an advance over existing tests, which look for just one virus at a time. But for now, they see the one-stop, $25 test as useful for research purposes, rather than real-world diagnostics. "It's hard to say how far off any clinical application could be," said Tomasz Kula, one of the researchers on the study and a graduate student at Harvard University in Boston. More immediately, Kula said, the test – called VirScan – could aid research. "One example would be studies that look for correlations between people's viral ... Read more

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Researchers Report Progress in Making All Blood Types Universally Accepted

Posted 21 May 2015 by Drugs.com

THURSDAY, May 21, 2015 – Scientists are closing in on a way to transform any type of donated blood into type O, the universal blood type that can safely be given to any patient. Researchers have created a special enzyme that can shear off the substances on red blood cells that are responsible for potentially fatal immune reactions if a patient receives the wrong type of blood, according to a new study. The enzyme is not yet effective enough to allow for large-scale processing to convert type A or type B blood into type O, said lead author David Kwan, a postdoctoral fellow of chemistry at the University of British Columbia's Centre for Blood Research in Vancouver, Canada. "We're not there yet. This is really a step towards that," Kwan said. "The big thing is that we've shown that it's feasible to improve these enzymes." Results of the study were published online recently in the Journal ... Read more

Related support groups: Blood Disorders, Bleeding Disorder, Anemia, Blood Transfusion, Blood Cell Transplantation, Anemia Prior to Surgery, Exchange Transfusion

Gene Mutations Tied to Leukemia Rise With Age, Study Finds

Posted 26 Feb 2015 by Drugs.com

THURSDAY, Feb. 26, 2015 – For many people, an increase in genetic mutations that could trigger leukemia seems to be an inevitable part of aging, a new study finds. The British researchers looked specifically at mutations in blood stem cells. "Over time, the probability of these cells acquiring mutations rises," co-lead author Thomas McKerrell, of the Wellcome Trust Sanger Institute, said in an institute news release. "What surprised us was that we found these mutations in such a large proportion of elderly people," he added. In the study, researchers looked at more than 4,200 people without any evidence of blood cancer. They found that up to 20 percent of people aged 50 to 60, and more than 70 percent of people older than 90, have blood cells with the same gene changes seen in leukemia. Just carrying a particular mutation doesn't mean that a leukemia is guaranteed, however. "Leukemia ... Read more

Related support groups: Blood Disorders, Leukemia

Many Kids Who Undergo Stem Cell Transplants Must Return to Hospital

Posted 24 Apr 2013 by Drugs.com

WEDNESDAY, April 24 – Nearly two-thirds of children who received stem cell transplants were readmitted to the hospital within six months for treatment of problems such as infections and unexplained fevers, a new study finds. Children who were given stem cells donated by other people were twice as likely to be readmitted as those who received their own stem cells, said the researchers at Dana-Farber/Children's Hospital Cancer Center in Boston. "No one had ever looked at these data in children," Dr. Leslie Lehmann, clinical director of pediatric stem cell transplantation, said in a cancer center news release. "This is very important information and will allow us to counsel families appropriately, as well as try to devise interventions that reduce the rate of readmissions." Lehmann and Harvard Medical School student David Shulman analyzed the medical records of 129 children who had stem ... Read more

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Off-Label Use of Clotting Drug Soars, Report Finds

Posted 18 Apr 2011 by Drugs.com

MONDAY, April 18 – Hospitals are using a pricey blood-clotting drug in treating people who do not have hemophilia, a rare disorder in which blood does not clot normally – even though its use in such patients is potentially risky, according to new research. Stanford University researchers found that use of the drug, known as recombinant factor 7a, grew by 140 times from use in 125 cases in 2000 to 17,813 in 2008, with off-label uses accounting for most of the increase. The $10,000-a-dose drug was used in people with hemophilia just 4 percent of the time, according to U.S. hospital statistics from 2000 to 2008. The rest of the time, it was used during heart surgery and to treat medical problems such as trauma and bleeding in the brain. The researchers content that such use puts patients at risk for heart attack and stroke because the drug can boost the risk of blood clots. "The stakes ... Read more

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Gene Rx May Fight Severe Blood Disorder

Posted 15 Sep 2010 by Drugs.com

WEDNESDAY, Sept. 15 – Patients suffering from a severe, inherited blood disorder may one day benefit from a new gene therapy and no longer need regular blood transfusions, new research suggests. However, far more study is needed to determine whether the therapy is safe and effective. So far only one patient has received the experimental treatment, and the researchers have followed him for only three years. The blood disorder – beta-thalassemia – occurs when a crucial blood protein known as beta globin is missing from the red blood cells that carry oxygen. Without beta globin, many of the red blood cells die off, causing severe anemia and eventually death if the person goes untreated. Beta-thalassemia mostly affects people of Mediterranean, Middle Eastern, Southeast Asian and Chinese descent. Some 100,000 children are born with the disease each year around the world, according to the ... Read more

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Anemia, Bleeding Disorder, Lymphoma, Protein S Deficiency, Leukemia, Protein C Deficiency, Myeloproliferative Disorders, Leukocytosis, Exchange Transfusion, Cryoglobulinemia, Hemoglobinopathy

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