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Bacterial Infection Blog

Related terms: Infection, Bacterial

Antibiotics Often Prescribed Needlessly for Terminally Ill, Study Finds

Posted 6 days ago by Drugs.com

WEDNESDAY, July 16, 2014 – Antibiotics are given to many hospice patients, although there's little proof the medicines benefit them, a new study shows. About 21 percent of patients who go directly from hospitals to hospice care for the terminally ill leave the hospital with an antibiotic prescription, even though more than one-quarter didn't have an infection while in the hospital, the researchers found. Also, 27 percent of hospice patients are still taking antibiotics in their final week of life, according to the study published online recently in the journal Antimicrobial Agents and Chemotherapy. The extensive use of antibiotics in hospice patients raises concerns because the underlying goal of hospice care is to control pain and protect quality of life without aggressive medical treatment. Risks of antibiotic use include harmful side effects, a lengthening of the dying process and ... Read more

Related support groups: Bacterial Infection

Mice Study Sees Link Between Gut Bacteria, Immune Cell Production

Posted 28 Mar 2014 by Drugs.com

FRIDAY, March 28, 2014 – Gut bacteria influence the production of immune cells that act as the first line of defense against infection, a new mouse study finds. If validated in humans, the findings eventually could lead to new therapies to sustain and increase people's immune function, according to the researchers from Cedars-Sinai Medical Center in Los Angeles. Experts note, however, that results achieved in animal studies often aren't able to be replicated in humans. Previous studies found that gut bacteria affect immune cell activity, but it wasn't known if they also played a role in immune cell production. This new research found that immune cell production was defective in mice that lacked gut bacteria. These mice were more likely to develop bacterial infections. The investigators said immune cell replenishment is necessary to fight infection. "We now have a clearer understanding ... Read more

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More Drug-Resistant Infections Seen in U.S. Children

Posted 20 Mar 2014 by Drugs.com

THURSDAY, March 20, 2014 – A growing number of American children are developing infections caused by a worrisome type of antibiotic-resistant bacteria, a new study report. While still rare, the bacteria are being found more often in children of all ages, especially those who are 1 to 5 years old, the study found. Investigators analyzed samples collected from children nationwide between 1999 and 2011 to assess the prevalence of the antibiotic-resistant type of bacteria called Enterobacteriaceae, which produces an enzyme called extended-spectrum beta lactamase (ESBL). The enzyme defeats many strong antibiotics, the study authors said. The researchers also measured ESBL prevalence by looking at rates of resistance to third-generation cephalosporins, which are an important class of antibiotics used to treat many infections. The prevalence of ESBL-producing bacteria rose from 0.28 percent ... Read more

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Many Hospitals Ineffectively Treat Bloodstream Infections, Study Suggests

Posted 18 Mar 2014 by Drugs.com

TUESDAY, March 18, 2014 – More than one-third of community hospital patients with serious bloodstream infections receive inappropriate antibiotic treatment, according to a new study. Most Americans use community care hospitals, rather than those that provide highly specialized care (tertiary care centers), according to the authors of the study, which was published March 18 in the journal PLoS One. "Our study provides a much-needed update on what we're seeing in community hospitals, and, ultimately, we're finding similar types of infections in these hospitals as in tertiary care centers," said study lead author Dr. Deverick Anderson, an associate professor of medicine at Duke University. "It's a challenge to identify bloodstream infections and treat them quickly and appropriately, but this study shows that there is room for improvement in both kinds of hospital settings," Anderson added ... Read more

Related support groups: Bacterial Infection, Septicemia

Eye-Catching Labels Urged for Fast-Tracked Antibiotics

Posted 3 Mar 2014 by Drugs.com

SUNDAY, March 2, 2014 – More than 30 medical organizations and health experts are asking lawmakers on Capitol Hill to add a new, attention-grabbing label to certain antibiotics to prevent them from being prescribed inappropriately. To speed up the process by which new antibiotics are made available to people with serious or life-threatening drug-resistant infections, lawmakers introduced the Antibiotic Development to Advance Patient Treatment (ADAPT) Act last year. This legislation will provide a pathway for new potentially life-saving drugs to be approved based on smaller clinical trials, as opposed to traditional large, clinical trials since drug-resistant infections affect a limited number of patients. Although the drugs must still meet U.S. Food and Drug Administration standards for safety and effectiveness, they are intended for use in this limited and specific group of people, ... Read more

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Many U.S. Hospitals Fall Short in Preventing Infections

Posted 19 Feb 2014 by Drugs.com

WEDNESDAY, Feb. 19, 2014 – Many U.S. hospitals don't follow rules meant to protect patients from preventable and potentially deadly infections, a new study shows. Researchers examined adherence to infection control policies in more than 1,600 intensive care units at 975 hospitals across the nation. They focused on three of the most common types of preventable infections in hospitals: central line-associated bloodstream infections; catheter-associated urinary tract infections; and ventilator-associated pneumonia. About one in 10 hospitals did not have checklists to prevent bloodstream infections, and one in four did not have checklists to prevent ventilator-associated pneumonia. About one-third of hospitals had no policy to prevent catheter-associated urinary tract infections. "Hospitals aren't following the rules they put in place themselves to keep patients safe," team leader Patricia ... Read more

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Decline of Antibiotic Use Among Kids Seems To Be Leveling Off: Study

Posted 4 Feb 2014 by Drugs.com

TUESDAY, Feb. 4, 2014 – A downward trend in antibiotic use among children may have leveled off in certain areas of the United States, a new study shows. Researchers from Boston Children's Hospital and Harvard Medical School reviewed data from three health plans across the country – in New England, the Midwest and the Mountain West – from 2000 to 2010 to better understand how antibiotics are being prescribed in children and to learn if use is still dropping. "This latest report finds that the decline in antibiotic use may have leveled out," said Dr. Louise Elaine Vaz, a clinical fellow in pediatric infectious disease and a health services research fellow at Boston Children's Hospital. The 10-year study included children between the ages of 3 months and 18 years. The researchers collected information on diagnoses as well as the type of antibiotics used, although certain antibiotics and ... Read more

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ERs Not Curbing Overuse of Antibiotics, Study Reveals

Posted 24 Jan 2014 by Drugs.com

FRIDAY, Jan. 24, 2014 – The inappropriate use of antibiotics among adult patients at U.S. emergency departments is not falling, despite increasing concerns about antibiotic resistance, a new study reveals. Improper antibiotic use is a contributing factor to antibiotic resistance, the University of Alabama at Birmingham researchers noted. They analyzed U.S.-wide data collected from 2001 to 2010 and found that there was no decrease in emergency department use of antibiotics for adults with respiratory tract infections such as sinusitis and bronchitis, even when those infections were caused by a virus. Antibiotics are not effective against viruses, the study authors pointed out. The use of antibiotics to treat children with respiratory infections decreased during that time, according to the study published online recently in the journal Antimicrobial Agents and Chemotherapy. During the ... Read more

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Can Bacterial Infections During Pregnancy Raise Autism Risk?

Posted 2 Jan 2014 by Drugs.com

THURSDAY, Jan. 2, 2014 – Pregnant women who have a bacterial infection that's diagnosed during hospitalization may be at greater risk of delivering a child with autism, a new study suggests. These infections – usually of the genitals, urinary tract or amniotic fluid – may lead to a nearly 60 percent greater risk of having a child with autism spectrum disorder, the researchers said in a paper published recently in the Journal of Autism and Developmental Disorders. But, the researchers added, such infections are very common during pregnancy and most don't lead to autism. Half the women included in the study had at least one infection during their pregnancy, regardless of whether their child is autistic. And the study only uncovered an association between bacterial infections and a child with autism – it did not prove cause-and-effect. "The vast majority of women who have infections ... Read more

Related support groups: Bacterial Infection, Autism

U.S. Spends 5 Times More Than U.K. on Antibiotics for Kids: Study

Posted 26 Dec 2013 by Drugs.com

THURSDAY, Dec. 26, 2013 – Antibiotics for children that are covered by private insurance cost five times more in the United States than in the United Kingdom, where costs are covered by a government universal health plan. That's the finding of researchers who looked at data from 160,000 U.S. and U.K. children younger than 10 years old who were prescribed one or more drugs in 2009. Antibiotics were given to 75 percent of the U.S. children and 50 percent of the U.K. children. The estimated cost of antibiotics covered by private insurers in the United States was more than $2.4 million, compared with less than $480,000 in the United Kingdom, according to the study, which was published in the current online issue of the journal Pharmacotherapy. The antibiotics commonly prescribed in the United States were regularly more expensive and taken for longer lengths of time, the investigators ... Read more

Related support groups: Bacterial Infection

FDA Wants Tighter Rules on Antibacterial Soaps, Body Washes

Posted 18 Dec 2013 by Drugs.com

MONDAY, Dec. 16 – The U.S. Food and Drug Administration said Monday that it wants makers of antibacterial hand soaps and body washes to prove their products are safe for long-term daily use and more effective than regular soaps in preventing illness and the spread of certain infections. Unless companies can do that, they would have to reformulate or re-label these products if they want to keep them on the market, the agency said. "Millions of Americans use antibacterial soaps and body washes," Dr. Sandra Kweder, deputy director of the FDA's Office of New Drugs, Center for Drug Evaluation and Research, said during a morning press briefing. "They are used every day at home, at work, at schools and in other public settings where the risk of bacterial infection is relatively low," she said. "We at the FDA believe there should be clearly demonstrated benefits from using antibacterial soaps ... Read more

Related support groups: Bacterial Infection, Triclosan, Bacti-Stat, Septisol, Cetaphil Antibacterial, Digiclean E, Aktif, Gel-X, Asept, Septi-Soft, Cadisept, Digiclean, Aquasept, Digiclean Slim-Line, Antiseptic Hand Soap, Sanygel

FDA Medwatch Alert: Cefepime For Injection, USP And Dextrose Injection, USP By B. Braun Medical Inc.: Recall - Visible Particulate Matter

Posted 16 Oct 2013 by Drugs.com

ISSUE: B. Braun Medical Inc. is voluntarily recalling one lot of 1g Cefepime for Injection USP and Dextrose Injection USP (Lot H3A744, catalog 3193-11) to the consumer level. The 1g Cefepime for Injection USP and Dextrose Injection USP lot has been found to contain visible organic particulate matter in a reserve sample unit. Visible particulate matter, including metals, and organic material such as cotton fibers or hair, may illicit inflammatory responses, both chronic and acute, and may be life threatening (e.g. systemic inflammatory response syndrome (SIRS and / or anaphylaxis). If a right to left cardiac shunt is present, the particulate may lead to arterial emboli and result in stroke, myocardial infarction, respiratory failure, and loss of renal and hepatic function or tissue necrosis. Other adverse effects associated with intravenous injection of particulate matter include foreign ... Read more

Related support groups: Bacterial Infection, Cefepime, Maxipime

'Cycling' Antibiotics Might Help Combat Resistance, Study Suggests

Posted 26 Sep 2013 by Drugs.com

THURSDAY, Sept. 26 – Doctors might be able to overcome antibiotic-resistant bacteria by swapping out the antibiotics used to treat a patient, providing a "one-two" punch that keeps the germs reeling, a new Danish study suggests. The strategy relies on a concept called "collateral sensitivity," in which bacteria that become resistant to one antibiotic also become more vulnerable to other antibiotics. The researchers argue that by swapping between antibiotics that play well off each other, doctors can stay one step ahead of bacteria and continuously avoid resistance. "You cycle between drugs that have reciprocal sensitivities," explained study co-author Morten Sommer, a lead researcher with the Novo Nordisk Foundation Center for Biosustainability at the Technical University of Denmark. "If you become resistant to drug A, you will become more sensitive to drug B. That way, you can cycle ... Read more

Related support groups: Doxycycline, Bactrim, Cephalexin, Bacterial Infection, Azithromycin, Cipro, Levaquin, Ciprofloxacin, Zithromax, Keflex, Sulfamethoxazole, Erythromycin, Minocycline, Bactrim DS, Clarithromycin, Methicillin-Resistant Staphylococcus Aureus Infection, Levofloxacin, Avelox, Biaxin, Tetracycline

Bacterial 'Autopsy' Could Speed Antibiotic Discovery: Study

Posted 20 Sep 2013 by Drugs.com

FRIDAY, Sept. 20 – Scientists say they've found a quicker way to analyze chemicals with bacteria-killing abilities in an advance they hope will speed the development of new antibiotics. With bacterial infections becoming increasingly resistant to existing antibiotics, new drug development is crucial, according to Dr. Stuart Levy, president of the Alliance for the Prudent Use of Antibiotics. "There's a real need for new antibiotics," said Levy, a professor at Tufts University School of Medicine in Boston who was not involved in the new study. There are still questions about the novel testing method described in the study, according to Levy, "but it's a step in the right direction." The approach, detailed in the Sept. 16-20 issue of Proceedings of the National Academy of Sciences, could make it simpler for researchers to figure out how a bacteria-killing chemical works. That's important ... Read more

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Gene Testing Helps Sort Out Bacterial, Viral Infections

Posted 18 Sep 2013 by Drugs.com

WEDNESDAY, Sept. 17 – A new genetic test that distinguishes between viral and bacterial infections could help fight antibiotic resistance and quickly detect new diseases, according to a new study. The immune system responds differently when battling a viral or bacterial infection, and these differences are evident at the genetic level. This new blood test detects a specific genetic signature that a person's immune system expresses in response to viruses, the Duke University Medical Center researchers said. They assessed the test in 102 people and found that it was more than 90 percent accurate in distinguishing between viral and bacterial infections in people with respiratory illnesses, according to the study, which was published in the Sept. 18 issue of the journal Science Translational Medicine. The findings move the test closer to clinical use, where it could help patients get ... Read more

Related support groups: Bacterial Infection, Viral Infection

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