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Bacterial Infection Blog

Related terms: Infection, Bacterial

FDA Approves New Formulation of Minocin (minocycline) for Injection

Posted 13 days ago by Drugs.com

PARSIPPANY, N.J.--(BUSINESS WIRE)--Apr. 20, 2015-- The Medicines Company (NASDAQ:MDCO) today announced that the U.S. Food and Drug Administration (FDA) has approved a supplemental new drug application (sNDA) for a new formulation of Minocin (minocycline) for Injection. The FDA has also granted Qualified Infectious Disease Product (QIDP) designation for the new formulation of Minocin for Injection under the Generating Antibiotic Incentives Now Act (GAIN Act). The designation, the third granted to a product in the Company’s infectious disease portfolio, would qualify Minocin for Injection for priority review and five years of marketing exclusivity upon an approval of the additional potential indications. Multi-drug resistant Acinetobacter is considered to be a serious antimicrobial resistance threat by the US Centers for Disease Control and Prevention (CDC). CDC estimates the number of d ... Read more

Related support groups: Bacterial Infection, Minocycline, Minocin

Simpler Antibiotic Regimen Helps Sick Babies in Developing Nations

Posted 2 Apr 2015 by Drugs.com

WEDNESDAY, April 1, 2015 – Newborns and young infants in developing nations who have suspected severe bacterial infections can be effectively treated outside a hospital, two new studies suggest. The findings indicate that the World Health Organization's guidelines on treating newborns and young infants with possible bacterial infections – such as pneumonia and sepsis (blood infection) – should be altered, the researchers said. About one in five babies worldwide develops severe bacterial infections during the first month of life, leading to about 700,000 deaths in newborns every year, the researchers explained. Current WHO guidelines recommend that newborns and young infants believed to have such infections be hospitalized and treated with antibiotic injections for at least seven to 10 days. However, many parents in developing nations can't afford, or don't have access to, such ... Read more

Related support groups: Amoxicillin, Bacterial Infection, Pneumonia, Amoxil, Sepsis, Amoxil Pediatric Drops, Trimox, Biomox, Moxatag, DisperMox, Apo-Amoxi, Moxilin, Wymox, Amoxicot

FDA Tightens Rules on Endoscopes Tied to 'Superbug' Outbreaks

Posted 12 Mar 2015 by Drugs.com

THURSDAY, March 12, 2015 – The U.S. Food and Drug Administration on Thursday issued final recommendations for the cleaning and sterilization of medical devices used in invasive procedures. The updated rules, first proposed in 2011, were released in response to last month's reports of seven serious infections and two deaths at Ronald Reagan UCLA Medical Center in Los Angeles, which were caused by duodenoscopes contaminated with a "superbug." On March 4, four similar "superbug" infections were reported at Cedars Sinai Hospital in Los Angeles. Duodenoscopes are devices used to diagnose and treat problems in the liver, pancreas and gallbladder. The FDA and the U.S. Centers for Disease Control and Prevention "have been devoting a great deal of effort to understand the circumstances and reasons for the episodes of drug-resistant bacterial infections associated with duodenoscopes," Dr. ... Read more

Related support groups: Infections, Bacterial Infection

2 Deaths, Scores of Potential 'Superbug' Infections at UCLA Med Center

Posted 19 Feb 2015 by Drugs.com

THURSDAY, Feb. 19, 2015 – At least 100 patients may have been exposed to medical devices contaminated with a "superbug" at the Ronald Reagan UCLA Medical Center in Los Angeles, where the devices are already believed to be responsible for seven serious infections, including two deaths. Endoscopes that were used to perform digestive procedures between October and January were contaminated with Carbapenem-Resistant Enterobacteriaceae (CRE), hospital officials said Thursday. The hospital said about 100 patients may have been exposed to the contaminated devices. The Associated Press reported that 180 patients might be at risk. Free home-testing kits are being delivered to all potentially infected patients, and UCLA will analyze the results, the medical center said. The two endoscopes thought responsible for the infections were used in the diagnosis and treatment of pancreatic and bile duct ... Read more

Related support groups: Infections, Bacterial Infection, Infection Prophylaxis

1 in 5 Sore Throats Tied to Scary Bacteria, Study Finds

Posted 16 Feb 2015 by Drugs.com

MONDAY, Feb. 16, 2015 – A potentially deadly bacteria is responsible for one in five sore throats in young adults, a new study suggests. Patients with this bacteria – Fusobacterium necrophorum – can get negative results on a strep test, but be at risk of an abscess that blocks the airway, researchers report. "If it looks like strep but it isn't strep, it could be this," said study author Dr. Robert Centor, a professor of medicine at the University of Alabama School of Medicine at Birmingham. Most sore throats get better without treatment, Centor said. But antibiotics should be prescribed when a patient "has a sore throat with fever, difficulty swallowing and swollen tonsils but a negative strep test," he said. In this study of young people aged 15 to 30, researchers found that more than 20 percent of the sore throats were caused by F. necrophorum – more than the number caused by ... Read more

Related support groups: Bacterial Infection, Strep Throat

Study Links Antibiotics to Digestive Complication in Infants

Posted 16 Feb 2015 by Drugs.com

MONDAY, Feb. 16, 2015 – Using certain antibiotics early in infancy may raise the risk of a serious gastrointestinal condition called pyloric stenosis, a new study indicates. Doctors have known that using the antibiotic erythromycin can increase the risk of pyloric stenosis in infants. The new findings confirmed that link, and also found that the antibiotic azithromycin (Zithromax) is associated with a higher risk of pyloric stenosis when given to infants under 6 weeks old. "Ingestion of oral azithromycin and erythromycin places young infants at increased the risk of developing [pyloric stenosis]," wrote the study authors, from the Uniformed Services University of the Health Sciences, in Bethesda, Md. "This association is strongest if the exposure occurred in the first two weeks of life, but persists, although to a lesser degree, in children between 2 and 6 weeks of age." However, it's ... Read more

Related support groups: Bacterial Infection, Azithromycin, Zithromax, Erythromycin, Chlamydia Infection, Zithromax Z-Pak, Erythrocin, Z-Pak, Ery-Tab, Pertussis, Azithromycin Dose Pack, E-Mycin, Zithromax IV, Zithromax TRI-PAK, Ilosone, EES Granules, EryPed, Zmax, EES-400 Filmtab, Robimycin

Certain Infections Linked to Reduced Risk of Rheumatoid Arthritis

Posted 5 Feb 2015 by Drugs.com

THURSDAY, Feb. 5, 2015 – People with recent gut, urinary tract or genital infections may be less likely to develop rheumatoid arthritis, new research says. The findings are "particularly interesting" in light of recent research suggesting that digestive system bacteria may play a role in the development of rheumatoid arthritis, researchers from the Karolinska Institute in Stockholm, Sweden, said. The study included almost 6,500 people from Sweden. Their average age was 52. About 70 percent were women. More than 2,800 people in the group were diagnosed with rheumatoid arthritis between 1996 and 2009. According to the study, having a gut infection within the preceding two years was associated with a lower risk of rheumatoid arthritis by 29 percent. A urinary tract infection was associated with a 22 percent lower risk, while a genital infection was associated with a 20 percent lower risk. ... Read more

Related support groups: Rheumatoid Arthritis, Bacterial Infection

Infection Most Likely Cause of Hospital Readmission After Surgery

Posted 3 Feb 2015 by Drugs.com

TUESDAY, Feb. 3, 2015 – Infections are the most likely reason people end up back in the hospital after surgery, a new study finds. Of nearly 500,000 operations studied, 6 percent of the patients were readmitted for surgical complications within a month after their surgery, researchers found. The number one complication leading to readmission was surgical wound infection, said lead researcher Dr. Karl Bilimoria, an assistant professor of surgery at Northwestern University Feinberg School of Medicine in Chicago. "Readmissions after surgery are not due to mismanagement or poor care. They are related to well-known and well-accepted complications after surgery," Bilimoria said. He added that knowing why readmissions happen is the first step in reducing them. Currently, the U.S. Centers for Medicare & Medicaid Services can penalize hospitals for excessive readmission rates. "We don't have ... Read more

Related support groups: Surgery, Bacterial Infection

Certain Heart Drug, Antibiotic Combo Might Be Fatal for Seniors

Posted 2 Feb 2015 by Drugs.com

MONDAY, Feb. 2, 2015 – The combination of a widely used heart medication and a commonly prescribed antibiotic seems to more than double the risk of sudden death in seniors, a new study says. Spironolactone (brand name Aldactone) is a diuretic widely used in treating heart failure. It protects the heart by blocking a hormone that causes salt and fluid buildup. But taking spironolactone alongside the antibiotic trimethoprim-sulfamethoxazole (brand names Septra, Bactrim) can cause blood potassium to rise to potentially life-threatening levels, said study lead author Tony Antoniou, a scientist with the Li Ka Shing Knowledge Institute at St. Michael's Hospital in Toronto. "One of the consequences of a high potassium level is getting these irregular heart rhythms that can be quite dangerous and cause sudden deaths," Antoniou said. To test the potential hazards of this drug combination, ... Read more

Related support groups: Bacterial Infection, Bactrim, Arrhythmia, Heart Failure, Congestive Heart Failure, Spironolactone, Bactrim DS, Septra, Aldactone, Sulfamethoxazole/Trimethoprim, Septra DS, Cotrimoxazole, Sulfatrim, SMZ-TMP DS, Sulfatrim Pediatric, Co-trimoxazole, Cotrim, Bactrim Pediatric, Bactrim IV, Bethaprim

Older Antibiotic Still Works Against Staph Infections, Study Finds

Posted 17 Oct 2014 by Drugs.com

FRIDAY, Oct. 17, 2014 – An older antibiotic called vancomycin is still effective in treating dangerous Staphylococcus aureus bloodstream infections, a new study finds. The findings show that doctors should keep using vancomycin to treat Staphylococcus aureus infections even though there are several newer antibiotics available to do the job, University of Nebraska researchers said. They analyzed the outcomes of nearly 8,300 cases of Staphylococcus aureus bloodstream infections in the United States and several other countries. The overall death rate was 26 percent. The researchers concluded that vancomycin is still a safe and effective treatment in such cases. Their findings were published Oct. 15 in the Journal of the American Medical Association. "The study provides strong evidence that vancomycin remains highly useful," study leader Dr. Andre Kalil, an infectious diseases specialist ... Read more

Related support groups: Bacterial Infection, Vancomycin, Vancocin, Vancocin HCl, Vancocin HCl Pulvules, Lyphocin

Kids May Leave Hospital Sooner When Antibiotics Are Controlled

Posted 9 Oct 2014 by Drugs.com

THURSDAY, Oct. 9, 2014 – New research finds that children who are hospitalized get discharged sooner and come back less often when hospitals take extra efforts to control treatment that uses antibiotics. Some hospitals and other medical facilities have embraced "stewardship programs" designed to make it harder for physicians to prescribe antibiotic medications without a good reason. While antibiotics can often effectively treat and cure infections, their overuse has allowed certain germs to develop resistance and keep people sick despite the use of powerful drugs. "Studies have shown stewardship programs reduce antibiotic use and decrease the risk of antibiotic resistance, but this is the first to demonstrate that these programs actually reduce length of [hospital] stay and readmission in children," said Dr. Jason Newland, study lead author and medical director of patient safety and ... Read more

Related support groups: Bacterial Infection

FDA Medwatch Alert: Vancomycin Hydrochloride for Injection USP, Equivalent to 1 Gram Vancomycin (Sterile Powder) by Hospira, Inc.: Recall - Uncontrolled Storage During Transit

Posted 9 Oct 2014 by Drugs.com

ISSUE: Hospira, Inc. issued a voluntary nationwide user-level recall of one lot of Vancomycin Hydrochloride for Injection, USP, Equivalent to 1 g Vancomycin (Sterile Powder), NDC 0409-6533-01, Lot 35-315-DD with expiration date of 01 NOV 2015. The product may have experienced temperature excursions during shipment to a customer and then was further distributed by the customer. This recall is being carried out to the medical facility/retail level (both human and veterinary). BACKGROUND: There have been no adverse events or complaints reported for the affected lot. RECOMMENDATION: Anyone with an existing inventory of the recalled lot should stop use and distribution and quarantine the product immediately. Please notify all users in your facility. If you have further distributed the recalled product please notify any accounts or additional locations which may have received the recalled ... Read more

Related support groups: Bacterial Infection, Vancomycin, Vancocin, Vancocin HCl, Vancocin HCl Pulvules, Lyphocin

Infection Rates in Nursing Homes on the Rise: Study

Posted 8 Oct 2014 by Drugs.com

WEDNESDAY, Oct. 8, 2014 – Infection rates within U.S. nursing homes are on the rise, and that trend will continue until better hygiene practices are put in place, a new study suggests. "Infections are a leading cause of deaths and complications for nursing home residents and, with the exception of tuberculosis, we found a significant increase in infection rates across the board," study author Carolyn Herzig, of the Columbia University School of Nursing, said in a school news release. Her team analyzed data submitted by nursing homes to the U.S. Centers for Medicare and Medicaid Services between 2006 and 2010. They found rising rates of pneumonia, urinary tract infections, viral hepatitis, septicemia (blood infection), wound infections and multiple drug-resistant bacterial infections such as methicillin-resistant Staphylococcus aureus (MRSA). Urinary tract infections and pneumonia were ... Read more

Related support groups: Bacterial Infection

Hospitals' High Antibiotic Use May Boost Germs' Resistance: Study

Posted 7 Oct 2014 by Drugs.com

TUESDAY, Oct. 7, 2014 – About half of all U.S. hospital patients receive antibiotics, and these drugs are commonly the ones more likely to promote the growth of antibiotic-resistant bacteria, a new study found. "This is where the bad bugs spread, in the hospitals, because so many people are receiving antibiotics, and one of the only things that can spread are the antibiotic-resistant bugs," said Dr. Eli Perencevich, an infectious disease epidemiologist at the University of Iowa Carver College of Medicine. "We have to figure out better ways to reduce excess antibiotic use, and one way to do that is to get better at making diagnoses," he added. The study identified how many of more than 11,000 patients received antibiotics on a given day at one of 183 hospitals throughout the United States in 2011. The researchers found that 50 percent of these patients got at least one antibiotic, and ... Read more

Related support groups: Bacterial Infection, Cephalexin, Bactrim, Azithromycin, Cipro, Ciprofloxacin, Levaquin, Zithromax, Keflex, Sulfamethoxazole, Erythromycin, Clarithromycin, Methicillin-Resistant Staphylococcus Aureus Infection, Bactrim DS, Levofloxacin, Vancomycin, Avelox, Cefdinir, Biaxin, Cefuroxime

Docs More Likely to Prescribe Unneeded Antibiotics Later in Day: Study

Posted 7 Oct 2014 by Drugs.com

MONDAY, Oct. 6, 2014 – Doctors are more likely to prescribe unnecessary antibiotics for respiratory infections as the day progresses, a new study finds. It appears that doctors "wear down" throughout the day, making them more likely to make inappropriate decisions about antibiotics, according to the researchers from Brigham and Women's Hospital in Boston. "Clinic is very demanding and doctors get worn down over the course of their clinic sessions," study lead author Dr. Jeffrey Linder, of the hospital's division of general medicine and primary care, said in a hospital news release. "In our study we accounted for patients, the diagnosis and even the individual doctor, but still found that doctors were more likely to prescribe antibiotics later in their clinic session," he said. The researchers analyzed data from more than 21,000 visits by adults with acute respiratory infections to 23 ... Read more

Related support groups: Bacterial Infection

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Urinary Tract Infection, Bacterial Vaginitis, Tetanus, Methicillin-Resistant Staphylococcus Aureus Infection, Bacteremia, Streptococcal Infection, Fusospirochetosis - Trench Mouth, Actinomycosis, Cutaneous Bacillus anthracis, view more... Bartonellosis, Granuloma Inguinale, Tularemia (Rabbit Fever), Tularemia, Mycoplasma Pneumonia, Anthrax, Nocardiosis, Legionella Pneumonia, Brucellosis, Leprosy, Pertussis, Lemierre's Syndrome, Tuberculosis, Meningitis - Meningococcal, Atypical Mycobacterial Infection, Meningitis - Pneumococcal, Q Fever, Botulism, Diphtheria, Infectious Endocarditis, Meningitis - Streptococcus Group B, Meningitis - Haemophilus influenzae, Glanders, Infections

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