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Bacterial Infection Blog

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Older Antibiotic Still Works Against Staph Infections, Study Finds

Posted 17 Oct 2014 by Drugs.com

FRIDAY, Oct. 17, 2014 – An older antibiotic called vancomycin is still effective in treating dangerous Staphylococcus aureus bloodstream infections, a new study finds. The findings show that doctors should keep using vancomycin to treat Staphylococcus aureus infections even though there are several newer antibiotics available to do the job, University of Nebraska researchers said. They analyzed the outcomes of nearly 8,300 cases of Staphylococcus aureus bloodstream infections in the United States and several other countries. The overall death rate was 26 percent. The researchers concluded that vancomycin is still a safe and effective treatment in such cases. Their findings were published Oct. 15 in the Journal of the American Medical Association. "The study provides strong evidence that vancomycin remains highly useful," study leader Dr. Andre Kalil, an infectious diseases specialist ... Read more

Related support groups: Bacterial Infection, Vancomycin, Vancocin, Vancocin HCl, Vancocin HCl Pulvules, Lyphocin

Kids May Leave Hospital Sooner When Antibiotics Are Controlled

Posted 9 Oct 2014 by Drugs.com

THURSDAY, Oct. 9, 2014 – New research finds that children who are hospitalized get discharged sooner and come back less often when hospitals take extra efforts to control treatment that uses antibiotics. Some hospitals and other medical facilities have embraced "stewardship programs" designed to make it harder for physicians to prescribe antibiotic medications without a good reason. While antibiotics can often effectively treat and cure infections, their overuse has allowed certain germs to develop resistance and keep people sick despite the use of powerful drugs. "Studies have shown stewardship programs reduce antibiotic use and decrease the risk of antibiotic resistance, but this is the first to demonstrate that these programs actually reduce length of [hospital] stay and readmission in children," said Dr. Jason Newland, study lead author and medical director of patient safety and ... Read more

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FDA Medwatch Alert: Vancomycin Hydrochloride for Injection USP, Equivalent to 1 Gram Vancomycin (Sterile Powder) by Hospira, Inc.: Recall - Uncontrolled Storage During Transit

Posted 9 Oct 2014 by Drugs.com

ISSUE: Hospira, Inc. issued a voluntary nationwide user-level recall of one lot of Vancomycin Hydrochloride for Injection, USP, Equivalent to 1 g Vancomycin (Sterile Powder), NDC 0409-6533-01, Lot 35-315-DD with expiration date of 01 NOV 2015. The product may have experienced temperature excursions during shipment to a customer and then was further distributed by the customer. This recall is being carried out to the medical facility/retail level (both human and veterinary). BACKGROUND: There have been no adverse events or complaints reported for the affected lot. RECOMMENDATION: Anyone with an existing inventory of the recalled lot should stop use and distribution and quarantine the product immediately. Please notify all users in your facility. If you have further distributed the recalled product please notify any accounts or additional locations which may have received the recalled ... Read more

Related support groups: Bacterial Infection, Vancomycin, Vancocin, Vancocin HCl, Vancocin HCl Pulvules, Lyphocin

Infection Rates in Nursing Homes on the Rise: Study

Posted 8 Oct 2014 by Drugs.com

WEDNESDAY, Oct. 8, 2014 – Infection rates within U.S. nursing homes are on the rise, and that trend will continue until better hygiene practices are put in place, a new study suggests. "Infections are a leading cause of deaths and complications for nursing home residents and, with the exception of tuberculosis, we found a significant increase in infection rates across the board," study author Carolyn Herzig, of the Columbia University School of Nursing, said in a school news release. Her team analyzed data submitted by nursing homes to the U.S. Centers for Medicare and Medicaid Services between 2006 and 2010. They found rising rates of pneumonia, urinary tract infections, viral hepatitis, septicemia (blood infection), wound infections and multiple drug-resistant bacterial infections such as methicillin-resistant Staphylococcus aureus (MRSA). Urinary tract infections and pneumonia were ... Read more

Related support groups: Bacterial Infection

Hospitals' High Antibiotic Use May Boost Germs' Resistance: Study

Posted 7 Oct 2014 by Drugs.com

TUESDAY, Oct. 7, 2014 – About half of all U.S. hospital patients receive antibiotics, and these drugs are commonly the ones more likely to promote the growth of antibiotic-resistant bacteria, a new study found. "This is where the bad bugs spread, in the hospitals, because so many people are receiving antibiotics, and one of the only things that can spread are the antibiotic-resistant bugs," said Dr. Eli Perencevich, an infectious disease epidemiologist at the University of Iowa Carver College of Medicine. "We have to figure out better ways to reduce excess antibiotic use, and one way to do that is to get better at making diagnoses," he added. The study identified how many of more than 11,000 patients received antibiotics on a given day at one of 183 hospitals throughout the United States in 2011. The researchers found that 50 percent of these patients got at least one antibiotic, and ... Read more

Related support groups: Bactrim, Cephalexin, Bacterial Infection, Azithromycin, Cipro, Ciprofloxacin, Levaquin, Zithromax, Keflex, Sulfamethoxazole, Erythromycin, Bactrim DS, Clarithromycin, Methicillin-Resistant Staphylococcus Aureus Infection, Levofloxacin, Vancomycin, Avelox, Cefdinir, Biaxin, Cefuroxime

Docs More Likely to Prescribe Unneeded Antibiotics Later in Day: Study

Posted 7 Oct 2014 by Drugs.com

MONDAY, Oct. 6, 2014 – Doctors are more likely to prescribe unnecessary antibiotics for respiratory infections as the day progresses, a new study finds. It appears that doctors "wear down" throughout the day, making them more likely to make inappropriate decisions about antibiotics, according to the researchers from Brigham and Women's Hospital in Boston. "Clinic is very demanding and doctors get worn down over the course of their clinic sessions," study lead author Dr. Jeffrey Linder, of the hospital's division of general medicine and primary care, said in a hospital news release. "In our study we accounted for patients, the diagnosis and even the individual doctor, but still found that doctors were more likely to prescribe antibiotics later in their clinic session," he said. The researchers analyzed data from more than 21,000 visits by adults with acute respiratory infections to 23 ... Read more

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Hog Workers May Bring Drug-Resistant Bacteria Home

Posted 15 Sep 2014 by Drugs.com

FRIDAY, Sept. 12, 2014 – About half the workers at industrial hog farms likely carry drug-resistant bacteria in their noses after they leave the farms at the end of their shift, a new small study suggests. What's more, that bacteria can stay with them for up to four days, reports the study. The longer the potentially harmful livestock-associated Staphylococcus aureus bacteria remains in the workers' noses, the greater the chances they'll spread the bacteria to their families, other people in the community and hospitals, the researchers said. "Before this study, we didn't know much about the persistence of livestock-associated strains among workers in the United States whose primary full-time jobs involve working inside large industrial hog-confinement facilities," study author Christopher Heaney, assistant professor in the departments of environmental health sciences and epidemiology ... Read more

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Aqua Pharmaceuticals Announces FDA Approval of Acticlate (doxycycline hyclate USP) Tablets

Posted 28 Jul 2014 by Drugs.com

West Chester, Pa. — July 28, 2014 West Chester-based Aqua Pharmaceuticals, an Almirall company, today announces the U.S. Food and Drug Administration (FDA) approval of the NDA for Acticlate (doxycycline hyclate USP) Tablets, 150 mg and 75 mg, thereby continuing Aqua’s leadership in medical dermatology and oral antibiotics for acne. Acticlate is a tetracycline-class antibacterial indicated for the treatment of a number of infections, including adjunctive therapy in severe acne. Acticlate will be entering the dermatology-focused, branded oral antibiotic market, which, according to IMS, is currently valued at $798 million. Acticlate 150 mg tablets have two functional scores, providing several dosing options to physicians and patients. The Acticlate film-coated, round 75 mg tablets and oval-shaped, dual-scored 150 mg tablets are designed to be small and easy to swallow. Utilization of the la ... Read more

Related support groups: Acne, Doxycycline, Bacterial Infection, Doxycycline Hyclate

Antibiotics Often Prescribed Needlessly for Terminally Ill, Study Finds

Posted 16 Jul 2014 by Drugs.com

WEDNESDAY, July 16, 2014 – Antibiotics are given to many hospice patients, although there's little proof the medicines benefit them, a new study shows. About 21 percent of patients who go directly from hospitals to hospice care for the terminally ill leave the hospital with an antibiotic prescription, even though more than one-quarter didn't have an infection while in the hospital, the researchers found. Also, 27 percent of hospice patients are still taking antibiotics in their final week of life, according to the study published online recently in the journal Antimicrobial Agents and Chemotherapy. The extensive use of antibiotics in hospice patients raises concerns because the underlying goal of hospice care is to control pain and protect quality of life without aggressive medical treatment. Risks of antibiotic use include harmful side effects, a lengthening of the dying process and ... Read more

Related support groups: Bacterial Infection

Mice Study Sees Link Between Gut Bacteria, Immune Cell Production

Posted 28 Mar 2014 by Drugs.com

FRIDAY, March 28, 2014 – Gut bacteria influence the production of immune cells that act as the first line of defense against infection, a new mouse study finds. If validated in humans, the findings eventually could lead to new therapies to sustain and increase people's immune function, according to the researchers from Cedars-Sinai Medical Center in Los Angeles. Experts note, however, that results achieved in animal studies often aren't able to be replicated in humans. Previous studies found that gut bacteria affect immune cell activity, but it wasn't known if they also played a role in immune cell production. This new research found that immune cell production was defective in mice that lacked gut bacteria. These mice were more likely to develop bacterial infections. The investigators said immune cell replenishment is necessary to fight infection. "We now have a clearer understanding ... Read more

Related support groups: Bacterial Infection

More Drug-Resistant Infections Seen in U.S. Children

Posted 20 Mar 2014 by Drugs.com

THURSDAY, March 20, 2014 – A growing number of American children are developing infections caused by a worrisome type of antibiotic-resistant bacteria, a new study report. While still rare, the bacteria are being found more often in children of all ages, especially those who are 1 to 5 years old, the study found. Investigators analyzed samples collected from children nationwide between 1999 and 2011 to assess the prevalence of the antibiotic-resistant type of bacteria called Enterobacteriaceae, which produces an enzyme called extended-spectrum beta lactamase (ESBL). The enzyme defeats many strong antibiotics, the study authors said. The researchers also measured ESBL prevalence by looking at rates of resistance to third-generation cephalosporins, which are an important class of antibiotics used to treat many infections. The prevalence of ESBL-producing bacteria rose from 0.28 percent ... Read more

Related support groups: Bacterial Infection

Many Hospitals Ineffectively Treat Bloodstream Infections, Study Suggests

Posted 18 Mar 2014 by Drugs.com

TUESDAY, March 18, 2014 – More than one-third of community hospital patients with serious bloodstream infections receive inappropriate antibiotic treatment, according to a new study. Most Americans use community care hospitals, rather than those that provide highly specialized care (tertiary care centers), according to the authors of the study, which was published March 18 in the journal PLoS One. "Our study provides a much-needed update on what we're seeing in community hospitals, and, ultimately, we're finding similar types of infections in these hospitals as in tertiary care centers," said study lead author Dr. Deverick Anderson, an associate professor of medicine at Duke University. "It's a challenge to identify bloodstream infections and treat them quickly and appropriately, but this study shows that there is room for improvement in both kinds of hospital settings," Anderson added ... Read more

Related support groups: Bacterial Infection, Septicemia

Eye-Catching Labels Urged for Fast-Tracked Antibiotics

Posted 3 Mar 2014 by Drugs.com

SUNDAY, March 2, 2014 – More than 30 medical organizations and health experts are asking lawmakers on Capitol Hill to add a new, attention-grabbing label to certain antibiotics to prevent them from being prescribed inappropriately. To speed up the process by which new antibiotics are made available to people with serious or life-threatening drug-resistant infections, lawmakers introduced the Antibiotic Development to Advance Patient Treatment (ADAPT) Act last year. This legislation will provide a pathway for new potentially life-saving drugs to be approved based on smaller clinical trials, as opposed to traditional large, clinical trials since drug-resistant infections affect a limited number of patients. Although the drugs must still meet U.S. Food and Drug Administration standards for safety and effectiveness, they are intended for use in this limited and specific group of people, ... Read more

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Many U.S. Hospitals Fall Short in Preventing Infections

Posted 19 Feb 2014 by Drugs.com

WEDNESDAY, Feb. 19, 2014 – Many U.S. hospitals don't follow rules meant to protect patients from preventable and potentially deadly infections, a new study shows. Researchers examined adherence to infection control policies in more than 1,600 intensive care units at 975 hospitals across the nation. They focused on three of the most common types of preventable infections in hospitals: central line-associated bloodstream infections; catheter-associated urinary tract infections; and ventilator-associated pneumonia. About one in 10 hospitals did not have checklists to prevent bloodstream infections, and one in four did not have checklists to prevent ventilator-associated pneumonia. About one-third of hospitals had no policy to prevent catheter-associated urinary tract infections. "Hospitals aren't following the rules they put in place themselves to keep patients safe," team leader Patricia ... Read more

Related support groups: Bacterial Infection

Decline of Antibiotic Use Among Kids Seems To Be Leveling Off: Study

Posted 4 Feb 2014 by Drugs.com

TUESDAY, Feb. 4, 2014 – A downward trend in antibiotic use among children may have leveled off in certain areas of the United States, a new study shows. Researchers from Boston Children's Hospital and Harvard Medical School reviewed data from three health plans across the country – in New England, the Midwest and the Mountain West – from 2000 to 2010 to better understand how antibiotics are being prescribed in children and to learn if use is still dropping. "This latest report finds that the decline in antibiotic use may have leveled out," said Dr. Louise Elaine Vaz, a clinical fellow in pediatric infectious disease and a health services research fellow at Boston Children's Hospital. The 10-year study included children between the ages of 3 months and 18 years. The researchers collected information on diagnoses as well as the type of antibiotics used, although certain antibiotics and ... Read more

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