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Alzheimer's Drugs May Benefit Heart, Study Finds

Posted 5 Jun 2013 by Drugs.com

WEDNESDAY, June 5 – Drugs used to treat early-stage Alzheimer's disease may also reduce patients' risk of heart attack and death, according to a new study. Researchers followed more than 7,000 Alzheimer's disease patients in Sweden for more than three years. Those taking cholinesterase inhibitors had a 38 percent lower risk of heart attack, a 26 percent lower risk of death from cardiovascular causes such as stroke and a 36 percent lower risk of death from any cause, compared to those who did not take the drugs. Patients who took the highest recommended doses of cholinesterase inhibitors (ChEIs) had the lowest risk of heart attack or death – 65 percent and 46 percent lower, respectively, than those who never took the drugs, according to the study, which was published online June 5 in the European Heart Journal. "If you translate these reductions in risk into absolute figures, it means ... Read more

Related support groups: Heart Attack, Alzheimer's Disease, Aricept, Myocardial Infarction, Donepezil, Exelon, Galantamine, Cardiovascular Risk Reduction, Reminyl, Rivastigmine, Razadyne, Razadyne ER, Aricept ODT

Study Produces Mixed Results on Alzheimer's Drugs

Posted 7 Mar 2012 by Drugs.com

WEDNESDAY, March 7 – A new study offers up mixed results about two medications used to treat the symptoms of the memory-robbing disease known as Alzheimer's. While patients didn't get a major mental boost when doctors added the drug Namenda to their regimen when they were already taking Aricept, they did find that continuing Aricept – a commonly prescribed drug for Alzheimer's in the United States – seemed to help. The results, which appear in the March 8 issue of the New England Journal of Medicine, may seem a bit murky, especially because it's difficult to measure the effects of the drugs on day-to-day living. However, study author Dr. Robert Howard, a professor of old age psychiatry and psychopathology at the Institute of Psychiatry at King's College London, said both drugs are worth taking, possibly even together. "While these drugs will not stop or slow down the tragic course of ... Read more

Related support groups: Alzheimer's Disease, Aricept, Namenda, Donepezil, Memantine, Namenda XR, Aricept ODT

Some People With Alzheimer's Take Conflicting Drugs

Posted 28 Oct 2011 by Drugs.com

FRIDAY, Oct. 28 – Many Alzheimer's patients who take cholinesterase inhibitors to slow their brain disease also take drugs that counter the effects of those Alzheimer's medications, a new study says. Clinical trials have shown that cholinesterase inhibitors such as Aricept (donepezil) have a modest impact on the functional and cognitive decline caused by Alzheimer's disease, noted the researchers at the Group Health Research Institute in Seattle. "Cholinesterase inhibitors are today's primary therapy for slowing Alzheimer's disease," study leader Denise Boudreau said in an institute news release. "Anticholinergic properties are often found in drugs commonly used to treat gastrointestinal disorders, allergies, urinary incontinence, depression and Parkinson's disease, and they can have negative effects on cognition and function in the elderly. There's concern that if someone is taking ... Read more

Related support groups: Benadryl, Diphenhydramine, Alzheimer's Disease, Aricept, Oxybutynin, Meclizine, Dramamine, Cogentin, Benztropine, Donepezil, Exelon, Ditropan, Scopolamine, Oxytrol, Benadryl Allergy, Artane, Trihexyphenidyl, Bonine, Antivert, Dimenhydrinate

FDA Approves Generic Aricept to Treat Dementia Related to Alzheimer's Disease

Posted 16 Dec 2009 by Drugs.com

ROCKVILLE, Md., Dec. 16, 2009-The U.S. Food and Drug Administration approved the first generic versions of Aricept (donepezil hydrochloride) orally disintegrating tablets on Dec. 11. Donepezil hydrochloride is indicated for the treatment of dementia related to Alzheimer's disease. Orally disintegrating tablets dissolve on the tongue, without having to be swallowed whole. This may make it easier to take the medication for older or disabled patients who have difficulty swallowing. "Generics offer greater access to health care for all Americans," said Gary Buehler, director of the FDA's Office of Generic Drugs. "Health care professionals and consumers can be assured that FDA-approved generic drugs have met the same rigorous standards as the brand-name drug and are the same as the branded in dosage form, safety, strength, route of administration, quality, performance characteristics and ... Read more

Related support groups: Aricept, Donepezil, Aricept ODT

Drug May Stem Slide Into Alzheimer's for Some

Posted 15 Jun 2009 by Drugs.com

MONDAY, June 15 – Depression might increase the chance of developing Alzheimer's disease among those already experiencing memory problems, a new study says. But the drug donepezil (Aricept), commonly prescribed for people with Alzheimer's, could slow the depressed person's slide into the disease, the study also found. The findings are reported in the June 16 issue of Neurology. "Our longer-term findings add to the body of evidence that suggests depression is a major risk factor for Alzheimer's disease," study author Po H. Lu, an assistant professor of neurology at the David Geffen School of Medicine at the University of California, Los Angeles, said in a news release from the American Academy of Neurology. The researchers' conclusions stemmed from a three-year study of 756 middle-aged and older people diagnosed with mild cognitive impairment, in which the memory is worse than would be ... Read more

Related support groups: Depression, Aricept

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