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Clues to How Popular Heartburn Drug Might Harm Arteries

Posted 18 days ago by Drugs.com

TUESDAY, May 10, 2016 – A popular over-the-counter heartburn medication accelerated aging of blood vessel cells in lab tests, raising red flags about its long-term effect on heart health, researchers say. Faster aging of blood vessel cells exposed to the antacid Nexium (esomeprazole) might potentially hinder the tasks these cells perform to prevent heart attack and stroke, the new study suggests. These lab results could explain why other studies have shown increased risk of heart disease in people who use proton pump inhibitors (PPIs) – the class of heartburn medication that includes Nexium, said study senior author Dr. John Cooke. "Our finding that the lining of blood vessels is impaired by proton pump inhibitors is a unifying mechanism for the reports that PPI users are at increased risk for heart attack, stroke and renal failure," said Cooke, chair of cardiovascular sciences at the ... Read more

Related support groups: GERD, Omeprazole, Nexium, Prilosec, Indigestion, Protonix, Pantoprazole, Dexilant, Prevacid, Lansoprazole, Tums, Milk of Magnesia, Aciphex, Caltrate, Duodenitis/Gastritis, Calcium Carbonate, Esomeprazole, Rabeprazole, Zegerid, Sodium Bicarbonate

Health Tip: Taking Antacids

Posted 1 Sep 2015 by Drugs.com

-- Over-the-counter antacids are generally safe to help ease heartburn. But, there are some people who should check with their doctor before taking them. The American Academy of Family Physicians says you should get your doctor's OK if you: have kidney disease, are postmenopausal, have had a Clostridium difficile infection, are elderly, have a compromised immune system. Read more

Related support groups: Indigestion, Tums, Milk of Magnesia, Caltrate, Calcium Carbonate, Sodium Bicarbonate, Phillips' Milk of Magnesia, Mylanta, Magnesium Hydroxide, Rolaids, Maalox, Aluminum Hydroxide, Oyster, Titralac, Oyster Shell, Titralac Plus, Os-Cal, Gelusil, Tempo, Os-Cal 500

Chronic Heartburn May Raise Odds for Throat Cancer: Study

Posted 23 May 2013 by Drugs.com

THURSDAY, May 23 – People who suffer from frequent heartburn may be at increased risk for cancers of the throat and vocal cords even if they don't smoke or drink alcohol, a new study says. Interestingly, common over-the-counter antacids seemed to protect against these cancers while prescription medications such as Prilosec, Nexium and Prevacid didn't, the researchers said. "There has been a controversy about whether heartburn contributes to cancers of the larynx or pharynx," said lead researcher Scott Langevin, a postdoctoral research fellow at Brown University in Providence, R.I. "And we found out that it does elevate the risk of these cancers. There is about a 78 percent increase in the risk for cancer in people who experience heavy heartburn," he said. "This is important in figuring out who to monitor more closely." The other finding, which Langevin called "surprising," was the ... Read more

Related support groups: Cancer, GERD, Omeprazole, Nexium, Prilosec, Indigestion, Prevacid, Lansoprazole, Tums, Milk of Magnesia, Caltrate, Calcium Carbonate, Esomeprazole, Sodium Bicarbonate, Phillips' Milk of Magnesia, Mylanta, Prilosec OTC, Magnesium Hydroxide, Rolaids, Aluminum Hydroxide

Health Tip: Call Your Doctor Before You Take Antacids...

Posted 15 Apr 2011 by Drugs.com

-- Antacids are medications that counteract acids in the stomach, to help ease heartburn discomfort. Many of these drugs are sold over-the-counter. But not everyone should take antacids, despite their wide availability, the American Academy of Family Physicians says. The academy mentions these people who shouldn't take antacids without first consulting a physician: People who are passing bloody stools. People who are vomiting blood. People who have heartburn that doesn't get better after two weeks of treatment. People who have painful or difficulty swallowing. People who are losing weight for no apparent reason. Read more

Related support groups: Tums, Milk of Magnesia, Caltrate, Calcium Carbonate, Gaviscon, Sodium Bicarbonate, Phillips' Milk of Magnesia, Mylanta, Magnesium Hydroxide, Rolaids, Aluminum Hydroxide, Maalox, Titralac, Oyster, Oyster Shell, Titralac Plus, Os-Cal 500, Acid Relief, Tempo, Os-Cal

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GERD, Hyperphosphatemia, Erosive Esophagitis, Duodenal Ulcer, Zollinger-Ellison Syndrome, Peptic Ulcer, Indigestion, Gastrointestinal Hemorrhage, Stomach Ulcer, Gastric Ulcer

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