I have just started taking generic Effexor ER 75 mg. My dr told me to take it in the morning, but the first 2 days it made me so tired, I called and said the pharmicist said if it made me tired to take it at bedtime was that OK, and he said yes, so I did that last night and was awake from 12:30 on, along with taking an Ambien at bedtime. I'd like to know when do others take their dose? Does the symptom of tiredness go away? Any other help you can provide is much appreciated. Thank you kindly