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If by raw you mean it is like open skin then perhaps you shouldn't use it.
"Do not use fluorouracil topical on skin that is irritated, peeling, or infected or on open wounds. Wait until these conditions have fully healed before using fluorouracil topical".
It would be better if you confirmed it with your prescriber, just to be sure what his/her intention is.
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Data sources include Micromedex™ [Updated 26 October 2009], Cerner Multum™ [Updated 18 November 2009], Wolters Kluwer™ [Updated 9 November 2009] and others. To view our editorial policy, content sources and attributions please click here.
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