Skip to Content

Is it safe to mix Tramadol and Zoloft?

Question is Closed
Report Favorite

Answers (2)


28 Aug 2013

Interactions between your selected drugs

sertraline ↔ tramadol
Applies to: Zoloft (sertraline), tramadol
Talk to your doctor before using sertraline and traMADol. This can cause altered consciousness, confusion, poor muscle coordination, abdominal cramping, shivering, pupillary dilation, sweating, high blood pressure, and high heart rate.

Click on the link for the full interaction:,2057-1348

Votes: +0

29 Aug 2013

I have been taking Zoloft, 150 mg and recently threw out my back. The doc gave me Tramadol and I did fine. He also put me on Prednisone for a week and that went alright too.
Hope this helps.

Votes: +0

Further Information

Search for questions

Still looking for answers? Try searching for what you seek or ask your own question.

Similar questions

Can you take a small dose of tramadol and a small dose of zoloft?

My mom was prescribed zoloft for depression, but she's already on tramadol. Her doctor and the pharmacist said it was okay if she took both of ...

4 answers 28 Feb 2010

I just took two 10mg of Tremadol, I'm on 200mg Zoloft. Has anyone experienced serotonin toxicity?

I wasn't thinking and took the tramadol before double checking for drug interactions. Is 200mg high for Zoloft?

4 answers 27 Oct 2010

Is it safe to take suboxone and Zoloft together?

I am taking 4mg of Subs daily and recently I've been having anxiety and depression issues and my doctor gave me Zoloft... But I'm kinda ...

4 answers 15 Sep 2011

Dr perscribed 50mg tramadol while on 50mg Zoloft. Should I cut Zoloft to 25 mg?

I'm worried about serotonin syndrome so should I take 25 mg Zoloft instead of 50 on days I need to take tramadol? I have torn disc that's ...

8 answers 27 Jul 2014

Is it safe to mix naproxen 500 mg with oxycodone acetaminophen 5-325?

I have really bad tendonitis aka tennis elbow in one of my tendons not all four, is it safe to mix the anti-inflammatory with the pain med?

1 answer 23 Jul 2015