... Approximately 2 hours. If I get up and walk it does not stop the pain. I am on celebrex and lipator and read in an article about restless leg syndrome to take lyrica as they were experminting with this drug. I had some lyrica left over from a previous prescription and began taking it a week ago its 100 ml. I take one every night at 8pm and sleep thru the night not waking to any pain in my leg. My question is am I safe taking these 3 prescriptions? And for how long should I take lyrica for the pain as I don't wake to the pain but the area where the pain was is senative