I have just been put on this drug, although my DR's have been trying to get me to take it for many years, I was reluctant, because i have heard that it was twice as strong as Oxycontin, and i was on 120 mg 4 x a day along with 30 mg of Roxicodone 4 x a day as well, now i am on Opana er 80 mg 2 40 mg pills at once 3x a day, plus 1 10 mg in morning and 1 10 mg at night. And i have to say I am very surprised, the medication is not working that well.. I know there has been a complication, in the new pills, but even still i was taking the octagon shaped ones, and they still did not seem to alleviate my pain, and now since my pharmacy, only had a partial supply about7 days worth, the Opana was the Octagon shaped ones, but the remainder of the prescription, is the new round pill with an E on one side and 40 on the other, which basically do nothing for eliminating my pain, or at least getting be to a comfortable position. I know i am rambling a bit, bcuz i am severely Pissed off. People who abuse these meds ruin it for people like us who are in chronic pain, who wouldn't be able to get up in the morning. ! following thing, why must I take the tablets and then wait 2 hours before eating? Every other medication seemed to work better if I ate food with the pain meds. Should I always take on empty stomach? And does anyone know of another medication which is equivalent to Opana ER 90 Mg 3x a day. I have heard EXALGO Er, but my Dr is very hesitant to write it. I have been on Fentanyl patches,Ms contin, Oxycontin,Methadone, TO any one who has been hurt as long as me, you know that meds like Percocet just don't cut it anymore.PLEASE GIVE ME SOME INSIGHT SOMEONE. I am at my wits end here. ANYONE WITH ANY INFO< WOULD BE HELPFUL, THANKS GUYS!
15 Jul 2013
My doctor put me on Exalgo er 10 and i just could not take it, i tried for one week. IT did nothing for my pain at all, i had many side effects from the medicine. It gave me indigestion, dry mouth,sweats and i could not urinate. I took that for seven days and i just could not do it anymore. So i told my doctor and he put me on opana 10 er i have to say the opana seems much weaker after taken the exalgo er 10. I am still back to where i started still in severe pain, nothing seems to help me
2 Jun 2012
Good morning NYG,
I believe Exalgo is a step down from Opana which is oxymorphone and Exalgo is hydromorphone or dilaudid. And I agree the new formulations don't work worth a poop. My only suggestion would be all IR Opana or Subutex or Suboxone. Amazing medication. Relieved my pain, the maximum dose of either the subs may work for you. If your PM doc can't prescribe the subs, he can refer you to a doc who can.
Peace and wishing you much luck and decreased pain,
2 Jun 2012
What they did to opana er was make the coating supposedly impossible to crush. That is why it takes so long to start working. Once it is in your system, like the others say, it should work better. Once again we're paying for the abuser who was crushing them and killing themselves, just like oxy. Do you take any other meds? There are some meds that hinder the absorption of other meds.
28 Aug 2012
Unfortunately, it's my understanding that almost everyone who has received the new third formulary "crush proof" Opana ER tabs with the new "plastic isomer" coating (which was manufactured by the same people who changed OxyContin OC to OxyContin OP), regardless of the dose, have not been been very pleased at all with the results, as well as the cost... OMG! I was first prescribed Opana ER 20mg 3x's daily (90 tabs @ approx. $901.00 retail) and received the original stop sign shaped tabs and was absolutely amazed at the positive initial results. No side effects at all, almost like a no medication feeling with appropriate pain relief, but the pharmacy only had a one week supply.
When I picked up the remainder of the 'scrip (the new "biconcave" shape, with "E" on one side and "20" on the other), it was the third formulary and I was in withdrawals within approx. 2 days due to the new coating and it's poor absorption rate. It was absolutely necessary for me to take these 1-2 hrs. before eating, or 2-3 hrs. after eating and even then, it takes at least 1.5 hrs. to feel ANY pain relief at all which was usually inadequate at best.
Fortunately, my dr. switched me over to the generics (oxymorphone hydrochloride ER and IR), which don't have the tamper proof coatings on them, (these too are costly, although not nearly as much as the brand)... but the only manufacturer producing the generic ER (Actavis) is presently only turning them out in 7.5mg and 15mg tabs. This situation is soon to change (Watson has a Sep. 2012 release date of their generic Opana ER in all dosages... 5, 10, 20, 30 and 40 mg tabs without the tamper proof coating and another manufacturer (Impax Labs) is due to have their version released in Jan. 2013 of the same dosages, also without the tamper proof coating) and there's already a generic for the IR type of Opana in both 5mg and 10mg tabs (made by Roxane and one or two other manufacturers), which seems to work quite well for me...
One more thing to consider in switching over to another med., Opana ER/IR is approx. 2-3x's stronger than meds like MsContin or any other morphine based medication. It's been my personal experience that Opana ER/IR is at least 2x's stronger than OxyContin, so be sure to discuss this with your dr. before making the decision to switch to another med... btw, Exalgo ER is a Dilaudid formulation and during my last visit to the pain dr., she told me that the FDA was puting a daily dosage cap on certain 'scrips of pain meds... OH BOY!!! Here we go...
19 Dec 2012
My dad was prescribed opana er 40 mgs.. but after they changed formula, he switched to a lower dose. There is a generic company that makes them in 15mgs and 7.5mgs. They are a lot stronger.. white or grey round with a crescent moon logo for activis.. that is the manufacturer. Check then out.. even if you have to take more at a time, you can still take the same daily dose.. just a lesser dose more times a day and that will help with the pain throughout the day. Ask you doc to prescribe you 15 mgs tablets instead .of 40mg.. you won't regret
2 Jun 2012
I don't know if this will help you or not, but have been trying to find a conversion chart for you, but they refer the doctor to their own charts, but if you look at this it will tell you why it has to be taken on an empty stomach. apparently it can interreact with certain foods. I agree about regular pain meds, with me also food seems to make them work better. I take my oxycodone & then eat a bite of something. If I don't well, no pain relief. Lots of reading here, but it does give a slight conversion, & chapter 12.3 tells about the food part. Hope this helps... Mary
2 Jun 2012
Hi Newyorkguy, do you happen to live by a compound only pharmacy? Your Dr can call your scripts in they only sliver and you will get the real thingnot this ne opana their making. If not I do no you NEED to take it on an empty stomach and wait at least. 2 hrs to eat. I weined off the opana 3 weeks ago but I ever had to take the new ones because I got mine from a compound pharmacy.
I didn't even no they released the new pain pill. Exalgo Er. I hear its supposed to be very strong compared to opana. Seems stupid they screw up oxycotin because if addicts come out with ooana now do the same to that just to come out with a even wickeder pain pill.
They'll ruin that soon enough.
I was on a slightly lower dose opana then you but higher oxycodone plus valuim when my Dr screwed up and I had no Dr. Then I was on opana only and that does not work with chronic pain & the idiot I was seeing gave me more opana for breakthrough pain. That does not work. 2 time released meds. So I refused to take them together & he said I was abusing my meds. Time for him to go. Now I'm just on methodone tabs and oxycodone. Smaller doses for now but I'll wok my way up. At least I'm not sick. Was waking up sick daily on opana only because it lasted 8 hrs tops & he counted so I could never take what I actually needed & without breakthru meds t was awful. At least you have backup. My advise to you would be try and cut down and get a second dose of oxycodone for breakthrough. Those opana unless you can find a ximpund pharmacy are not going to get better & your jut going to withdraw. Make it easy in yourself while you can. Your a lot Luke me.Ben on all the high narcs. Since I weined down.i Feel better and my tolerence is down for now. Sure it was rough but u have meds i had nothing but the wein down meds that my friends helped me thru it. Now its easier and its like starting fresh. But I have a good Dr which you seen to have already so come up with a plan with him and try it out. The higher your tolerence goes their just gonna keep screwing up the meds and you'll be screwed sooner or later.
Hope that helped. But try the empty stomach. I no that works for a fact and if it doesn't work with these new opana then go with Mary's suggestion. She's very knowledgeable.
Good luck. Let me no if it works. The compound oharmac told me the empty stomach thing. They said always take them on a empty stomach. Also try coffee if u drink it or Pepsi works too. They said food not drink. The caffeine kicks it in. Hit usually works better in time release. With the other cold us fine. Just a trick I learned yrs ago.
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