My son switched from Neoral to Prograf about a month and a half ago. Side effects?

Mood or mental changes is a serious side effect of Prograf. Please get your son seen by his doctor as soon as possible.

The other known side effects are:

Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Prograf:

Back pain; constipation; diarrhea; dizziness; headache; joint pain; loss of appetite; nausea; stomach pain or upset; trouble sleeping; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur when using Prograf:

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Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); dark urine; decreased coordination; chest pain; diabetes (frequent urination, increased thirst or hunger); fast or irregular heartbeat; fever, chills, or sore throat; mental or mood changes (eg, anxiety, confusion) one-sided weakness; painful urination or changes in the amount of urine; red, swollen, blistered, or peeling skin; seizures; severe or persistent dizziness or headache; shortness of breath; swelling of the hands, feet, or legs; tingling or numbness in the hands or feet; tremor; trouble speaking; unusual bruising or bleeding; unusual lumps or skin lesions; unusual weakness or tiredness; vision changes; yellowing of the skin or eyes.

http://www.drugs.com/sfx/prograf-side-effects.html