Is prednisone a steroid drug?
Prednisone is an FDA approved drug that is part of a medication class called corticosteroids, a grouping of steroid hormones. It is a synthetic glucocorticoid (cortisone-like drug) that works systemically, meaning it works all over your body. It mimics a steroid that your body already produces.
Prednisone can treat low levels of corticosteroids by replacing the naturally produced steroid. It can also treat other diseases by decreasing inflammation from inhibiting multiple substances in the chemical pathway of inflammation. It can also alter your body’s immune response by suppressing your immune system.
Prednisone is available as prescription-only oral tablets or oral solutions. Available brand names in the United States include Rayos or Sterapred. The initial dosage ranges from 5 mg to 60 mg per day, depending on the condition being treated and your response to the medication.
Prednisone can be used to manage a broad range of diseases, including those affecting your:
- Skin
- Metabolic system
- Gut
- Blood
- Nervous system
- Eyes
- Lungs
- Kidneys
It is also used in treating autoimmune diseases, certain infectious diseases, severe allergies, some cancers and organ transplants.
Prednisone is absorbed in your gut. Therefore, it is best to take prednisone with food or milk to decrease stomach upset. When taking large doses, antacids may be recommended in between meals to help prevent peptic ulcers.
Related Questions
- What is considered a high dose of prednisone?
- Is it OK to drink alcohol with Prednisone?
- How long can you take prednisone safely?
Possible adverse effects of prednisone
Short-term side effects of prednisone may include:
- Increased appetite
- Weight gain
- Fluid retention
- Mood swings
- Insomnia
- Indigestion
- Increase in blood pressure
- Increase in blood glucose
Adverse effects are more common in higher doses or with long-term use.
Long-term effects may include:
- Mental changes
- Acne
- Facial hair in women
- Stomach ulcers
- Delayed wound healing
- Growth retardation in children
- Thin arms and legs
- Pink-purple stretch marks
- Cataracts
- Abnormal fat deposits
- Increased risk of infections and fractures
Extended use may eventually increase the risk for developing diabetes, hypertension, glaucoma, psychiatric conditions and osteoporosis.
References
- U.S. National Library of Medicine MedlinePlus. Prednisone. March 15, 2020. Available at: https://medlineplus.gov/druginfo/meds/a601102.html. [Accessed August 9, 2021].
- Puckett Y, Gabbar A, Bokhari AA. Prednisone. Apr 19, 2021. StatPearls. https://www.ncbi.nlm.nih.gov/books/NBK534809/.
- U.S. Food and Drug Administration (FDA). Rayos (prednisone) delayed-release tablets. July 2012. Available at: https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/202020s000lbl.pdf. [Accessed August 9, 2021].
- U.S. National Library of Medicine DailyMed. Prednisone tablet. June 1, 2020. Available at: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=f05eb734-07e7-491c-b2e9-aae340e03750. [Accessed August 9, 2021].
Read next
Related medical questions
- Do I take all 6 prednisone pills at once on the first day?
- How long does prednisone stay in your system?
- Why does prednisone cause weight gain?
- What are the side effects of steroids?
- Methylprednisolone vs Prednisone - How do they compare?
- Does prednisone make you sleepy?
- Can prednisone raise blood pressure?
- Prednisone vs Prednisolone - What's the difference?
- Is it safe to take ibuprofen right after taking prednisone?
- Does prednisone cause a rapid heart rate?
- Why is prednisone prescribed with Zytiga?
- I just took ibuprofen and prednisone, is that ok?
- Can you take prednisone with Keytruda?
- How long does it take prednisone to get out of your system?
- Is sunburn a side effect of prednisone? Should I avoid being in the sun while taking prednisone?
- Can you take Xanax if you are on prednisone?
- Can you take Symbicort and prednisone together?
- Are there any drug interactions between prednisone and Viagra?
Drug information
- Prednisone Information for Consumers
- Prednisone prescribing info & package insert (for Health Professionals)
- Side Effects of Prednisone (detailed)
Related support groups
- Prednisone (328 questions, 1,077 members)