I am extreamely manic and have insomnia. I am on xanax and have started taking prozac. what are the symtoms that may occur, if any, by mixing the two? So far, they work great for mania and insomnia. In other words they work well for me,
12 Aug 2015
I am on Prozac 40mg and Xanax 2mg and it has changed my life for the better. I also take other medications however, I noticed the biggest change when Xanax was added. I felt like I could breathe again. The Prozac made me anxious sometimes and the Xanax also helped with that. My other medications are Tramadol and temazepam for sleep.
28 Apr 2012
I have put your two meds in the intereactor checker above in blue & here are the results:
alprazolam ↔ fluoxetine
Applies to: Xanax (alprazolam), Prozac (fluoxetine)
MONITOR: Fluoxetine may increase plasma alprazolam concentrations, decrease alprazolam clearance, and increase the elimination half-life of alprazolam. The mechanism may be related to inhibition of CYP450 3A4 microsomal drug metabolism. This combination may impair psychomotor performance and reports have suggested that the risk of cardiac toxicity such as bradycardia may be increased.
MANAGEMENT: If fluoxetine and alprazolam must be used together, close observation is recommended for increased adverse effects. Patients should be warned about excessive drowsiness and potential adverse effects on their psychomotor and driving skills.
Hope this helps sort out any problems you may have... Mary
28 Apr 2012
If the combination is working well, then you are most likely just fine to take both meds. I don't know much about Bi-polar issues, yet have a good friend that has Bi-polar and he has taken anti-D's with Xanax for years and years with no side effects nor negative consequences.
I too take prozac and xanax with NO problems.
Wishing you all the best,
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