11 Nov 2009
Ranitidine and Prilosec (omeprazole) both work differently to reduce stomach acid.
Ranitidine is a H2 antagonist. It reversibly and competitively blocks histamine at H 2 receptors, particularly those in gastric parietal cells, leading to inhibition of gastric acid secretion.
Omeprazole is a proton pump inhibitor, a compound that inhibits gastric acid secretion. Omeprazole belongs to a class of antisecretory compounds, the substituted benzimidazoles, that suppress gastric acid secretion by specific inhibition of the H+/K+ ATPase enzyme system at the secretory surface of the gastric parietal cell. Because this enzyme system is regarded as the acid (proton) pump within the gastric mucosa, omeprazole has been characterized as a gastric acid-pump inhibitor, in that it blocks the final step of acid production. This effect is dose-related and leads to inhibition of both basal and stimulated acid secretion irrespective of the stimulus. Animal studies indicate that after rapid disappearance from plasma, omeprazole can be found within the gastric mucosa for a day or more.
Hope you find this useful.
Search for questions
Still looking for answers? Try searching for what you seek or ask your own question.
Sucralfate - I have been on Prilosec for many years I have been on Plavix for 4 months The prilosec?
... is not working.My dr. is presciping carafate I would like your opion
1 answer • 4 Aug 2009
I have been told I have a hiatus hernia and have been experiencing pain in my back and my chest.
9 answers • 15 Feb 2010
My acid reflux is much worse after taking Savella and starting on Gabapentin.
1 answer • 17 May 2010
1 answer • 29 Jan 2013
Now my insurance won't pay because it's available OTC. The OTC says to take for only 14 days and is 20.6 mg so is obviously not the same ...
0 answers • 19 May 2015