11 Nov 2009
Ranitidine and Prilosec (omeprazole) both work differently to reduce stomach acid.
Ranitidine is a H2 antagonist. It reversibly and competitively blocks histamine at H 2 receptors, particularly those in gastric parietal cells, leading to inhibition of gastric acid secretion.
Omeprazole is a proton pump inhibitor, a compound that inhibits gastric acid secretion. Omeprazole belongs to a class of antisecretory compounds, the substituted benzimidazoles, that suppress gastric acid secretion by specific inhibition of the H+/K+ ATPase enzyme system at the secretory surface of the gastric parietal cell. Because this enzyme system is regarded as the acid (proton) pump within the gastric mucosa, omeprazole has been characterized as a gastric acid-pump inhibitor, in that it blocks the final step of acid production. This effect is dose-related and leads to inhibition of both basal and stimulated acid secretion irrespective of the stimulus. Animal studies indicate that after rapid disappearance from plasma, omeprazole can be found within the gastric mucosa for a day or more.
Hope you find this useful.
Search for questions
Still looking for answers? Try searching for what you seek or ask your own question.
the protonix was making my jaws hurt and making me have more breathing issues like short breaths every now and again do you think prilosec will help ...
1 answer • 15 Aug 2009
I am taking Doxycyline long term and unless I take it first then eat immediately, I get severe heartburn. I have a prescription for Prilosec and ...
1 answer • 15 Sep 2009
1 answer • 29 Jan 2013
A few years back during high school I was diagnosed with a hiatal hernia. To help treat this I was given Ranitidine (Zantac) 150mg... it wasn't ...
1 answer • 10 Jul 2013