27 Feb 2011
Interactions between your selected drugs
No results found - however, this does not necessarily mean no interactions exist. ALWAYS consult with your doctor or pharmacist.
Other drugs that your selected drugs interact with
Flextra (acetaminophen/caffeine/phenyltoloxamine) interacts with more than 300 other drugs.
Zipsor (diclofenac) interacts with more than 200 other drugs.
Interactions between your selected drugs and food
caffeine ↔ food
Applies to: Flextra (acetaminophen/caffeine/phenyltoloxamine)
The effect of grapefruit juice on the pharmacologic activity of caffeine is controversial. One report suggests that grapefruit juice increases the effect of caffeine. The proposed mechanism is inhibition of cytochrome P-450 metabolism of caffeine. However, a well-conducted pharmacokinetic/pharmacodynamic study did not demonstrate this effect. The clinical significance of this potential interaction is unknown.
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