I am taking 12 & 25 patch & by 2nd day I start getting a rash & itching. My pharmacist thinks I'm allergic to the adhesive used since I am sensitive to all medical tapes except paper tape. My doc won't let me change every 48hrs so by 72 I'm going crazy with itching, oh also taking benedryl orally to help the itching. Doc gave me steroid cream but after a month the original sites are still not back to normal. It is almost as if the skin is scarred. I'm running out of sites to put the patches on. I can't put on upper back because I use heat on this area. I don't see what the big deal is in changing patch 48 vs. 72 sense I thought the patches released the drug amount steadily at an hourly rate. Any thoughts?