A good person on here asked me to post a question as I and so many others seem to be having terrible side effects from the new OP formulation that Purdue Pharma put out to make tamper proof so that abusers couldn't cut them open anymore.
I started the new OP on 9/6 feeling as good as I ever can with RSD in chronic pain with this being the only long acting opiate that not only ever helped my pain but also that I wasn't severely allergic to.
A few days before Tuesday, 9/14 I felt constipated attributing it to the new OP formula. On 9/14 I began vomiting knowing it was the medication/constipation problem. I stopped vomiting but the next day woke up feeling flu like symptoms with a fever of 100.9 and what is medically called; malaise which means a general feeling of being ill also with my stomach still out of sorts.
It is now day 17 on this new OP formula and I'm not as bad as I was on 9/14 through 9/18 but I'm still daily feeling ill, having a low grade fever, and my stomach just isn't right and I feel it gets worse after the usual time that it always took for the old formulation of OC to kick in; about 1 1/2 hours.
I feel I could have the same pain relief personally if I could take the amount I'm prescribed but my stomach won't allow it along with not being able to take the Percocet for breakthrough pain; usually 3 to 4 a day but with the stomach problems, I've only been able to take one most days; maybe a 2nd.
I called my pharmacist who has had other complaints of very similar symptoms that I reported. He didn't say how many but it didn't sound good.
I've had the same pharmacist for over 11yrs and he knows me well and does talk to me.
I have thought that maybe we are having withdrawals from the old formulation and it could take time for our bodies to adjust to the new OP formulation as the compounds have changed.
I am trying to not just psych myself out due to these side effects knowing that the compound change could be the problem and give it time to see if my stomach can handle this and start feeling better in general.
My doctor knows that ALL other long acting opiates that I have been prescribed have given me serious allergic reactions so I must have an extremely sensitive system. Last year I was even put on Opana and I couldn't breathe after taking only the 1st pill.
I would have already gone off of this entirely if there were other options for me but feel I have to give it a try.
I would like anyone who is taking this new OP kind and was on the old OC formulation to post here on this question and keep up to date with any side effects or symptoms they may be having as we just need to try to help each other here.
Maybe we can figure this out together. I was only able to take the dose I'm supposed to for the 1st 8 days so I also don't know if this is going to relieve my own chronic pain the way the OC did along with my breakthrough meds.
I see my doctor soon and will have to tell her what is going on after I figured out this was not a flu bug or virus but this new OP itself.
I was extremely upset as I tried to do an online search today only to find the drug abusers trying to figure out how to cut it open to abuse it more.
The people I've met here are usually genuine and together we can help each other.
I also promise to keep you up to date on my own issues and hopefully we can start feeling better soon.
Oxycontin side effects on new OP?
A good person on here asked me to post a question as I and so many others seem to be having terrible side effects from the new OP formulation that Purdue Pharma put out to make tamper proof so that abusers couldn't cut them open anymore.
Added 30 Oct 2010:
Please read: If you have called Purdue Pharma and they are sending you a form to fill out over the side effects of the new OP Oxycontin, please get the lot # from your pharmacy if it's not on your prescription bottle (which usually it isn't) or they won't be able to process your claim. I just received my form after calling them before September 20th and without the lot # they refuse to make it apart of the ongoing investigation.
Call your pharmacist as soon as possible if you are going to be part of Purdue's investigation so they can help us all.
Added 29 Nov 2010:
After taking the generic Ethex version of Oxycontin made in the same way as the old formula, I've found that in only 2mos none are now available for my prescription due this week. My pharmacist said that there is NO form of generic Oxycontin available now and only had some left overs in the 80mg dose only when I'm on the 40mg dose.
I took my script for November in and was only able to get 88 of the 90 pills prescribed to me. Due to my pharmacist's fear due to severe allergic reactions to ALL other long acting opiates, my pharmacist said he feels there is NO long acting formulation of any pain medicine that I could tolerate and could only recommend the 10mgs of Oxy IR in a generic version. That is breakthrough dosage for me as I'm on 10/325 of generic Percocet for that up to 6 times a day PRN.
I have refused any increases when the original Oxycontin was out for at least 8yrs and offered to me at least 7 times due to my own fear of any medication along with the age I was injured and my age now; 43 knowing this pain is for life as I see it now.
I would give ANYTHING to not have to need a medication like this. I have put a call to my doctor in and hope to get an answer by today or early tomorrow as she mentioned a medication that starts with an "N" and I've researched everything online I can even asking my pharmacist about other meds.
I fear now that if I have to go on another med that if I'm not allergic to it, I will go through euphoria again after not having this problem for around 5 or 6yrs.
At this point, I PRAY that the new Oxycontin OP is taken off the market completely as it's their 1.5 BILLION dollar a year baby that they've held a patent on for way too long and only because of their power of keeping this patent are we left with NO generic.
IF one is made eventually, it will probably be formulated like the OP.
I see a HUGE lawsuit against Purdue for doing what they have to the people I've read about on this site/post along with how many others not on this site who must have gotten ill due to this reformulation also.
I am a responsible pain patient who has never abused my medications as are so many of you here and why do we have to pay for abusers and junkies? So far there are NO widespread news reports about so many getting sick from OP version and we need a voice; our own and together we are strong.
I can hope for us that we can pull together to get a major network to do a story about what Purdue has done to us.
Added 19 Dec 2010:
UPDATE: My doctor finally got me off of any form of Oxycontin and now taking Kadian; it's working so much better than the OC ever did.
I began taking this in early December after going without any long acting opiate for a while and ending up in a wheelchair vs on a cane.
Even though I've always been honest telling any of my doctors that I am allergic to Morphine, I explained to my Int Med Doctor that the way I found this out was at least 6yrs or more before RSD/Chronic pain during an outpatient surgical procedure and only had IV Morphine and never took a synthetic Morphine pill since becoming "opiate tolerant".
She was brave enough to give me Kadian; a Morphine pill like MS Contin but better, and I was brave enough to begin to take it finding the best pain control I've ever had in my 11 1/2yrs in chronic pain.
This all worked out for the absolute best and now able to take less medication a day bc of it.
I hope others too are finding an even better medication for chronic/severe pain.
Added 23 Dec 2010:
Before being put on Kadian, she was afraid of my allergic reactions to some of these meds and only gave me Oxy IR 30mg 6 a day. That is closer to Percocet than a strong long acting pain med. That is how I ended up on a walker before seeing her again and realizing I had to have a long acting med, she gave me Kadian capsules 100mgs which equals about 80mg of OC.
60mgs equals 30 to 40mgs of OC.
I hope this helps as I know way too many who are/have suffered from this change.
14 Jan 2011
Wow! I wish I had read this post before I posted my question! There are a lot of us saying this medication doesn't work the same. I asked the pharmacist about whether they had any others saying the new formulation doesn't work as well and she looked at me funny and said "No. Not really complaints but a lot of people calling to see if we carry the old formulation. She said they changed the formula so people couldn't remove the coating any longer to get the medicine to release all at once and so it couldn't be injected because it gels up" I looked her straight in the eye and told her that I NEVER have altered my meds in any way and I dont think they work as well. I used to be able to take my OC in the morning and within 30-45 min I could feel the pain ease and my back start to relax. With the OP's this doesn't occur. It is sometimes 1-2 hours before I start feeling any relief.
I've always had trouble with the long acting formulas not working for the full 12 hours they are supposed to. I have to take mine every 8 hours. With the OP's I'm lucky if I get 3-4 hours of relief. I haven't had the nausea but I do notice inconsistant relief and an increase in headaches. I'm really frustrated and angry! I'm reluctant to talk to my pain doctor about the problem because I don't want him to think I'm seeking a high or think I'm abusing my medicine. I have tried other medicines and the old OC's seem to work the best. Now with the OP's I dont know what to do. I HATED Fentanyl! I bear scars on my chest from Fentanyl. It worked ok IF it stuck but most of the time I couldn't get it to stick even with the overlays that the drug company sent. I was lucky if it would stick for a day then it would get loose and puff up in the middle-well, it stands to reason that it can't work if it is not making contact with your skin. My then Dr wouldn't take me off them even when I showed him the redness and blistering the overlays and adhesives were causing. (This same guy had previously tried Methadone which gave me HORRIBLE headaches-he didn't want to change the Methadone either. He was giving me Compazine to help with nausea and finally one of the nurses in his office spoke up and said to him 'You can't leave her like that!' He then went to the Fentanyl and when I couldn't use that he dropped me as a patient because he didnt know what to do with me! Just as well, I didn't want to stay with him as I didn't think he knew what he was doing anyway!!) So you can see why I'm reluctant to say much to the Dr. I had a really good Dr a few years ago and she moved to CA and then I inheireted my current Dr when his colleague (who was also easy to work with) moved too. I'm not nearly as comfortable with this current guy but I hate to go somewhere new because everytime I change Drs I feel like I'm starting over. They each want to start at square one with their routine. Each one feels like they have some magic touch, I guess! LOL I think I'm going to have to talk to him next month. He wants me to stay away from my short acting breakthrough meds and I've had to take them a lot more with the OP's. Maybe I will see if a morphine type of long acting drug will work. I've had people say MS Contin, Kadian and Avinza all work really well so maybe he'd be willing to try one of those. I've tried the morphine long acting before, years ago, but I wasn't given a breakthrough med so I think that was why I felt like it didn't work well. Plus, then, the OC's seem to work best but I don't have that option anymore so maybe it would be worth trying again. I'm glad I found everyone on this site. It is good to know others who REALLY know what I'm going through. Most people I know have no idea what I'm going through and cant understand why I just cant take an Ibuprofen and shake it off and get on with things. It isn't that kind of pain-if you haven't experienced that kind of pain you have no idea!!
23 Sep 2010
i know exactly how you feel. i had takin oxycontin 4 a long time and the new OP formula didn't help my cronic pain much at all. i took it 4 less than a month and told my dr. he agreed that others had said things also. so i just gave him the rest of my months suppy and im trying fentanyl. but this is my 1st week on it and its not doing gd either. plus im having detox from the oxys. i sure hope i will be done soon its not fun. take care folks god bless
31 Oct 2010
Hi, I am having the same severe problems, and this is the 3rd month trying the op, I hate how sick that I am,is their anything that I can do too help us get back on the oc??? I was so very happy when the doc put me on oc. , finally after all this time, I got 100% pain relief, and after 3 years, I felt like my old self again. I am going too be 71 years old soon, can't I have my last years without severe pain, and now severe nausea, is their anyone out their can help me, please??God bless u all!!!
24 Oct 2010
I am happy to hear that I am not alone. There is now doubt in my mind that the new oxycontin formula is making me very ill. I have been on 80mg's every eight hours for two and a half years as well as 10mgs IR's every 3-4 hours prn. I have had 6 pelvic/abd surgeries and suffer from severs chronic pain now for the past 17 years. I first got a mix of oxycontin in sept, half were the old half were the new.
I did get generic and I always get brand in any long acting medication because they work better. Anyway I noticed that with the op I would not get any pain relief and after two hours I would get sick in the stomach and really funny in the head, not dizzy but unable to focus my mind was foggy and I could not even see right. I have been contipated like I have never been in my life. If I end up in the hospital with a bowel obstruction I could loose part of my colon and end up with a colostomy.. I did have bronchitis in sept so I was wandering if that was the problem. I called my doctor and he called in a z=pak and I recovered since. I am a respiratory therapist with 30 years medical experience so I do know a thing or two about the human body. Like right now as I write this I can hardly stay on topic.
Bottom line is this medication is not going to work for me. I am like many others angery. I finally found a combo of meds that worked and now I will have to start over again. My doctor is away so I will have to wait but I guess I will be returning to pain management and see if those doc's could help me out. I don't mind returning to the pain clinic but it is an hour and a half drive one way and of course a higher copay and my doctor retired so I would have to see one who does not really know me. Last week on the eveing news there was a segment about oxycontin. Since the new formula does not allow abusers to get the high they want and oxy is expensive they are returning to herion. Well good for them. God forgive me but I do not wish them good health for they have now taken away mine.
We need to speak out. If the formula is going remain then we need to change medications. I am considering Avinza. It is expensive but I did get pain relief from it in the past I just did not like feeling doppy,
Good Luck everyone and please do not be aftaid to speak out. I am calling the FDA and Purdue tomarrow. Would have done it sooner but I needed to be sure it was the new formula.
25 Jan 2011
I just wanted to add that I thank you for your updates. Who would have guessed there was a silver lining in all this, with Kadien working so much better for you than Oxycontin ever did.
But because of your success, maybe I won't be so afraid to try it if my doctor ever feels ready to prescribe it.
Could you please tell me in what way Oxycontin OP is a completely different medication? I thought it was the same but with different fillers. Do you know how can I find information about this to give to my doctor?
18 Oct 2010
I received my first prescription of 30 mg OP on October 4th. On Oct. 5th I was admitted to the hospital with severe gastric distress. I have stomach issues anyway and did not relate my hospital admission to the new OP till I was released from the hospital 4 days later and started doing some online research on the new oxycontin formula.
I am NOT getting the same pain relief with the new formula. I take 30 mg. every 8 hours and am only getting pain relief for about 3 hours out of every 8. It takes the pills apx. 2 hours to work, then I am knocked out sleeping for 2 to 3 hours. I then awaken in severe pain. That is a total of 5 hours from when I first take the pill. This leaves me in pain for 5 more hours- 3 more hours till I can take the next pill, 2 hours for it to work then back to sleep for 2 to 3 hours.
The old oc formula gave me a steady pain relief and the ability to function as a normal human being. This new formula has stolen any trace of a normal life. I am in constant pain, with stomach cramping and nausea 24/7. The old formula never made me sleepy or caused the gastric issues I am experiencing now. I HATE this new op formula. I only pray that my pain management dr. can find me an alternate pain med that will work as well as the old oc. If not then I have lost my quality of life and would be better off dead.
I also have a sensitivity to many medications and can not tolerate them. I have severe chronic pain, OA, lyme, and fibromyalgia. I am so disgusted with people like us being punished for what the drug abusers do.
14 Feb 2013
There's a huge difference between the OD and the new OP! I noticed the difference between the two on the first dose of OP I took. Sick to my stomach, headache,( which I very seldom get) a light headed feeling, constipation and a wierd hollow feeling in my stomach. I noticed I was watching the clock for my next dose , something I've never done in the 9 years I've been on OxyContin. I've now have moderate to sever abdominal pain, been to the ER once already due to the pain, i have a very over active stomach due to the OP, always gurgerling and making all kinds of loud noise's. I asked my Pain Management Dr about the OP and I was told she has a lot of complaints over the OP, almost everyone if her clients. This new pill is a nasty drug and I'm just waiting for a class action suit, it's just a matter of time. I've been tossing around a suit myself already. I hope this experience helps you, good luck.
26 Sep 2010
I was taking the oc version and have also been switched to the new op. Last months supply was 1/2 the oc and 1/2 the op so I didn't really notice anything too much. I just got this months supply and it is all the new op ones. (this was Friday 9/24) I have been very busy lately, doing a lot. My daughter got hurt in a soccer game on Thurs. night so Friday was taking her to the dr., so I sat quite a bit since the dr. is a hour away and sitting for long periods make my hips hurt more. Friday night I had to clean a house which aggravated (sp?) my lower back. Then Sat. we went grocery shopping (again sitting in the car for a hour there and hour back) and walking a lot shopping. ANYHOW... the result is I am in A LOT more pain. I realize I have done a lot more in the past few days but it doesn't seem like I am getting any relief what so ever from the pain med. The only thing helping is I have just a few instant release oxy pills.
I only have them because I am scheduled to have a facet block this Thurs. I wanted to save as many as I could for after the procedure but due to the increased pain I have had to take some of them. I have been trying to slowly wean myself off taking the oxycotin but if the new version isn't going to work as well then it's going to be hard to cut back. I hope this is making sense to you guys and I'm not just rambling on???
I was given a pamflet (i know i can't spell) when I got the new op pills. The #'s and web site listed are as follows if anyone need them:
For ?'s or concerns Purdue's Medical Service Dept: 1-888-726-7535, prompt # 1.
To report adverse reactions (side effects) Purdue Pharma L.P. at 1-888-726-7535, prompt #2 or to the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.
I guess I will just see how things keep going, if the pain lets up after awhile or if it continues, maybe the new pill don't work as well. Any advice and/or opinions are welcome.
26 Sep 2010
Id say try using Roxicodone 30mg for now because they are still the original formula and stay on those until Perdue has time to decide whether to change them or not. It will get you by until then. I know you will have to take more pills during the day but if it makes you pain go away without making you sick, then Id certainly be willing to go that route if it was me. Maybe they will end up changing the oxycontins again and then you can switch back. But at least for the time being you can be ok. Keep us updated with whatever you decide to do. The more information we all get from a direct source such as yourself, the more we can all help each other. Take care and good luck.
17 Jun 2013
I just stumpbled upon this post (even thoug I am clearly chiming in years later) and wanted to share my experience in the event something is found out to be hazardous to one's health.
I have had to take Oxycontin for about 5 years now due to an incurable disease affecting a major organ and when the new formula came out I did notice that they seemed to not provide as much pain relief.
Now, that I've read all the concerns of other people, I realize that I too, have had several health issues that have begun within the timeframe of when I started the new OP formula.
To begin, I now have IBS and regularly feel fatigued and achy all over. The biggest scare was two years ago when I had to have a tumor removed from my throat that had grown so fast it went from my throat all the way to bottom of my armpit!
Thank goodness, my surgery (overall) went well; however, I do have some permanent nerve damage that affect my eye on the side of my face where the tumor was present and I have a nasty scar to remind me of the event.
I'm writing this post in the event that other people put "two and two" together as I just did and think their health issues are in conjunction with the OP formula. ??? Best Wishes to everyone!
21 Oct 2010
I have been on the real oc for about six months and I got switch over to the new ones. sence I have been on the new ones I have not been able to have any bowle movements and i have had a sharp pain through my upperback and my right side of my chest in my breast area. also I woke up this morning around 5am and got a drink when I took my drink it felt like there was somethin dried up and stuck to my throat like it had to rip its self of and go down. Im not sure if it was the gel in them or what. I have also had the dizzyness to and its like the kind where u just gotta rest ur head cause ur eyes kinda go black. Im not sure if its all comming from this new pill but it didnt start intill last month when I got them.
10 Nov 2010
The manufacturer of the old style Oxycontin, Purdue Pharm, acquired Ethex Manufacturers to distribute the OC's for them. It's being marketed in generic form as Oxycodone ER in 80 mg & 40 mg only, but unfortunately only Walgreens is carrying this brand name. Let me warn you though, pretty much every pharmacy is very hesitant to give any information what so ever concerning Schedule II medications over the phone, unless they know you due to the rash of daytime robberies not too long ago looking for, you got it, Oxycontin!! There's one more company that distributes the 20 mg only, called Apotex. As far as I know once again, Walgreens only carries this. You must completely trust & believe me when I tell you, IT REALLY IS EXACTLY THE SAME MEDICATION. It's says OC on one side & 80 on the other, is the same exact color & same size.
It will begin to melt in your mouth, if for some reason you can't swallow it immediately, so that alone tells me they ARE NOT the OP's. The OP's gave me horrible stomach pains with worsened constipation. Worse of all (I'll swear on a mountain of Bibles, too!!) those darn things passed completely through my intestinal tract & on out completely whole, without dissolving at all. Now you tell me, how can a medication perform its duty if it can't break apart to let the chemicals do what they're suppose to do? Recently I read they've discovered yet another dangerous side effect from them. If you have a damaged liver, etc.,be careful because whatever they have used for the reformulation to make it abuse resistant, has the possibility of causing further or additional problems or damage.
I believe this is the longest response I've submitted since joining this valuable forum recently. This website has been so very helpful, supportive and been full of accurate knowledge on any question I've needed answers for. Thank you Drugs.com for being there for me.
I truly hope this give you the answers you seek & you're a little less stressed & the future looks a little bit more positive. Don't hesitate in letting me know if you need help with anything else...
19 Jan 2011
after having 4 fractures and in horrid pain my doctor refused to prescribe Oxycontin she told me the story about it was new and a formulation part was removed to prevent some individuals unlike Chronic pain people from abusing and shooting it up (I guess they melt it down and the component they removed if shot up made you rreally high now that they reformulated this that will not happen she said the serious thing the folks that needed it it was no effective and causing lots of problems and to add to the mix the pharmaceutical company got their original patent back she is going to update me if she hears more I am not on this but I am interested in hearing about this, I care about what happens to others who are in severe pain and I want to help in any way that I can I wish you only the very best
- OxyContin Information for Consumers
- OxyContin Information for Healthcare Professionals (includes dosage details)
- Side Effects of OxyContin (detailed)
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