When I fill my monthly generic prescription for oxycodone, I sometimes get pills made by different manufacturers. It seems like some work better than others, same dose - same drug! Does anyone else have this experience?
11 days ago
My Pain Management doctor says the FDA gives them 25% wiggle room. So, depending on the batch, for a 10 mg pill, you could get 7.5-12.5.
I had some Percocet that were terrible. I switched to Oxycodone alone because I figure with fewer ingredients you had a better chance of getting the oxy.
When you are in pain, it really matters that it is right!
17 Oct 2014
People including doctors and pharmacist will say they are the same claiming legally they have to be the same up to a slight legal difference that shouldn't be noticeable. I don't care what they say as someone that has taken them and know a lot of other people that do as well they do not all work as well. I will say most are the same can't even tell the difference but their are a few that fail and I mean by a lot. Some I can take quite a few of them more than prescribed and still nothing. I don't know how they get away with it. I'm speaking of the 10 mg ones and specifically the ones that have A333 and IP203 on them really suck. They should be investigated because they are cheating people.
31 Dec 2014
There is definitely a difference. All controlled substances have a number and letter or just numbers on it. Go to the area in drugs. com and type in the identifying number and or letters and it will tell you the ingredients. Way different and some don't have the ingredient of the ones that help
13 Dec 2014
While the amount of active ingredient is standardized across all generic formulations of any particular drug, due to variable excipients and formulation between different generic products, it is likely that different generic formulations will exhibit differences in drug bioavailability (which is ultimately a function of drug absorption, distribution, metabolism and elimination)- which will be influenced by the composition of the formulation.
6 Mar 2014
I have this exact same problem! Most generic brands of the 5mg oxycodone cause me a lot of problems... mainly itching and sever heartburn... I asked my doctor about this and he explained that it' s most likely not the oxycodone in it but the inert added ingredients that these generic manufactures put in as filler. I also asked why I can not always get the brand that does not cause me any problems or side effects, I asked my regular pharmacist and was told that the "big box" store where I get my prescriptions filled, is constantly shopping around for the cheapest deal on the scripts that they carry! So far the worst brand I have found is Caraco.
It makes me as sick as a dog, but I have no choice but to take it, if I go to a different pharmacy, my doctor gets upset and threatens to dump me as a patient! Also some of the cheaper generic brands use a whole lot of extra inert fillers, to make their product cheaper therefore the pharmacies will buy from them more often, even though the drugs are supposed to be identical... we all know they are not! And no, this brand does not work as well as some others do, all drugs are not created equal!
15 Nov 2015
Today even my doctors know that due to Obama care that yes,the generic alternatives are different from the brand name medications ,it is definitely not in your head,before you buy a generic equalivant I would advise you to google and find what works best for most people,the fda does not regulate the fillers that are added to the generic equalivant medications,some people are blind to the fact that the pharmaceutical industry is larger than any business,if the government has their way they will import the cheapest drugs from countries like China,India Japan,even though the active ingredient is equal,the fillers are different,why?Because the fillers act differently and are not absorbed properly in most people,they are left to show their own independent studies and report back to the fda,the government can buy boatloads of medication for a far cheaper price than most manfacturers can afford,let's face it,our healthcare system is in big trouble and cuts are being made every day in ...
order for it to stay afloat,cost are being cut across the board and some people still believe that generates are exactly the same,for those who choose to believe that their is no difference,do some research and if you dig deep enough,you will find it in black and white,there is a difference,and many people are beginning to find out that some of the medication is not working like it did in the past,cost cutting is indeed being applied,and it is making people sick,my advice is to be more proactive and find out what works best for you and definitely go with your instincts,then you don't have to listen to the so-called generic drugs are the same,because that is just not so,Cane0716
2 Jul 2013
I read on WebMD recently, that manufacturers of generic drugs have to have the same "main ingredients" as Brand name. They can add coloring, or change size and shape, but, otherwise have to work like the Brand. I have been taking meds for over 28+ yrs and some Brands feel better, but, most generics work just fine. Generics have to pass same regulations that Brand names do. Basically there is very little difference, and from what I read, must "act" in the same manner. WebMd is a pretty good source of info. Look it up there if you can for more info. Its not as personal as this site, but, they do have updated info on most anything you can think of. I like it here best because not only do I get information, I get ideas, reactions, personal experience, and so far, the people are really nice and smart. Still, basic Information is good to have too. Ta ke care and be well as can be...
9 Oct 2015
I have the same response to taking the oxycodone with the letter M*s 30 milligrams does not work for me I asked my doctor what is the difference in the lettering cuz the A*s work better for me and the k9*s work better for me. I wonder do they put different medicines in at different manufacturer if anybody knows the answer please let me know cause i have to go look for what works for me every month when it time for my refil.
8 Mar 2016
It is not in your head! I have been taking oxycodone and oxycontin for more years than I care to admit. There is a difference. There are at least half a dozen manufactures and 4 to 5 different number designations. A333 seems to work the best. There's another one that starts with IP which is pretty good too. They one to stay away from is the one that is about the same length as a Tylenol (the others are shorter). I actually got so tired of it that I had my doctor switch me to the straight oxycodone with no Tylenol in it. Those pills are consistent and I needed a stronger dose anyway and 10mg is the biggest one that includes Tylenol. The 20mg and 30mg pills are straight oxycodone, nothing else.
2 Jul 2013
I don't feel any difference betwixt my generic oxycodone, but hang in there, others will agree with you I'm quite sure.
Do you've a preference of manufacturers? If so, talk to your pharmacist to see if they'll order your favourite just for you, it may work!
Best wishes to you,
- Oxycodone Information for Consumers
- Oxycodone Information for Healthcare Professionals (includes dosage details)
- Side Effects of Oxycodone (detailed)
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