I quit smoking one year ago, and am now addictted to the 2mg lozenges.
will they hurt me? I am 70 years of age.
25 Mar 2013
I have been unable to locate any studies which looked at the effect of Polacrilex for prolonged periods of time.
Unfortunately, you will be experimenting on yourself as no long term studies are being planned, of which I am aware.
Madhup Joshi, MD
25 Mar 2013
I would really like to know, too, what the long term effects of just nicotine are. I have a lot of patients who have stopped smoking but use the "E cigarette" and they think they are fine because they have stopped smoking. I suppose you are at least not getting the carcinogens you get with smoking but e-cigarettes or lozenges, either one, are nicotine delivery systems and you are still addicted to the drug, nicotine. Nicotine initially causes a rapid release of adrenaline, the "fight-or-flight" hormone. This causes an elevated heart rate and increased blood pressure along with rapid breathing. Nicotine can stimulate abnormal proliferation of vascular endothelial cells, similar to that seen in atherosclerosis. Nicotine induces potentially atherogenic genes in human coronary artery endothelial cells.
Which basically means it can harden the arteries including the arteries in the heart which contributes to heart disease and prolonged high blood pressure. Over the long haul, nicotine can increase the level of the "bad" cholesterol, LDL, that damages your arteries. This makes it more likely that you could have a heart attack or a stroke. Nicotine has a major effect on brain chemicals including many of the "feel good" chemicals and this is what makes it so addictive. Nicotine is both stimulant and sedative depending on how much you use. 2mg is a fairly high dose. Sixty milligrams of nicotine (about the amount in three or four cigarettes if all of the nicotine were absorbed) will kill an adult, but consuming only one cigarette's worth of nicotine is enough to make a toddler severely ill. And every year, many children go to the emergency room after eating cigarettes or cigarette butts. Anti-smoking advocates highlight the long-term health effects, like cancer and emphysema, that result from a lifetime of smoking or chewing tobacco -- but these maladies are the result of chemicals in cigarettes other than nicotine. Unfortunately, the fact that nicotine alone is an extremely toxic poison often goes unmentioned. Not many people realize that nicotine is also sold commercially in the form of a pesticide! So whether you smoke or get the nicotine from an e-cigarette or gum or lozenges, you are still putting poison in your body! Something to think about.
- Nicotine Information for Consumers
- Nicotine Information for Healthcare Professionals (includes dosage details)
- Side Effects of Nicotine (detailed)
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