13 Aug 2010
Checked the Interactions between the 2 meds, and it has been recommended to be monitored:
Applies to: Lipitor (atorvastatin), Valturna (aliskiren/valsartan)
MONITOR: Coadministration with atorvastatin may increase the plasma concentrations of aliskiren. The exact mechanism of interaction is unknown but may involve competitive inhibition of the CYP450 3A4 metabolism of aliskiren. According to the product labeling, peak plasma concentration (Cmax) and area under the concentration-time curve (AUC) of aliskiren were increased approximately 50% by atorvastatin following multiple dosing. Aliskiren had no significant effect on the pharmacokinetics of atorvastatin.
MANAGEMENT: Caution is advised during coadministration of aliskiren with atorvastatin. Antihypertensive response should be monitored more closely following initiation, discontinuation, or change of dosage of atorvastatin in patients who are stabilized on their aliskiren regimen. Patients should be advised to notify their physician if they experience excessive adverse effects of aliskiren such as dizziness, lightheadedness, diarrhea, abdominal pain, and gastroesophageal reflux.
Please for technical details talk to the doc who prescribed the med, hope the info helps?
Search for questions
Still looking for answers? Try searching for what you seek or ask your own question.
I was told by my pharmacist that Valturna is no longer manufacturer and there is a "warning" is this true?
1 answer • 20 Sep 2012
My father's dose was doubled and he started having pain in arms and legs. He was taken off of the Lipitor but his arms are still in pain. He ...
2 answers • 1 Jan 2013
I've tried exercise and pain medication, to no avail, and I'm wondering if it could be the lipitor. A pharmacist told me "highly ...
2 answers • 18 Mar 2013
I am being treated by using special shoes and icing. It has gotten better, but still there. About 6 months ago I started Lipitor. Not sure if it is ...
1 answer • 11 Apr 2013
... 'bright' Rheumatologist diagnosed me w/RA and said it was not the Lipitor. After the Methotrexate she gave me almost killed me I threw ...
1 answer • 6 Jul 2013