Metadate ER - Is there a difference in Concerta and Methylphenidate ER.

I have spoken to several Drs. and Pharmacists, who have suggested that generics actually can make a difference in (lack of) efficacy of a medicine (not specifically Concerta, but in general). Depending on the "binders" that are used with the actual therapeutic ingredients of the drug, the generic medicine can either be less effective or can actually contribute to some other symptoms, although not necessarily mood swings. My mother refuses to take any generics because of this fact. She was once highly allergic to binders used in several of her meds., so as a general rule, subscribes to name brand only. I'm not sure if this is the case with Concerta, but it has been the case with other meds. Also, with generics, the proportions can be unequal to those measured carefully in name brand of same drug. Some generics can have more "binder", and not as much of the therapeutic ingredient. With my thyroid, I only take name brand.

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Some meds are just too important, I think, to take a chance on an incorrect proportion of ingreds. You might try a couple of months on name brand and then generic to see if there's a difference. It may also be time to switch meds, as sometimes meds. can change in their effect on the body as an individual's biochemistry changes. Good luck!