12 Mar 2006
As to your question about generic pain meds, yes, some are weaker than others. It all comes down to quality control at the facility of the manufacturer. The FDA allows generic meds, in the active ingredient, to differ by as much as plus or minus 20% from the original name brand.
Thus, if the company has poor quality control, and doesn't maintain rigorous testing of their pills as they produce them, you can end up with some pills that have large amounts of the active ingredient, some pills that have the correct amount, and some that have virtually NONE.
I, myself, have an Oxycodone instant release that I can take 3 times a day for breakthrough pain. I have had some that didn't do anything, I might as well have swallowed a tic tac, some that were fine, and others that made me sick like I had overdosed and taken too many, even though I only took one pill, and these were all in the same bottle!
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The pill you were asking about is manufactured by Mallinckrodt Pharmaceuticals and they have gained an awful reputation for making bad pills. If you do a search for information on their meds, you will pull up many BB sites, similar to this one, with everyone complaining about their products.
Now, on top of this difference, there are no requirements that the inactive ingredients, the fillers and binders, be the same as the name brands at all. The manufacturer can use whatever they choose, as long as they are on the FDA approval list for pill making. Some people have problems with these as well, as they can affect each person differently and how the pills main ingredient works in their body.
So while some generic meds are great, from companies that maintain high quality standards, some are awful and you get a double whammy if you don't react well to one of the inactives.