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I am taking heparin for asst. with clotting issue and IVF... this is the first time they have tested my heparin levels and it keeps coming back extremely low... like I am not even on it! They have upped the dose to 10,000 units 3 x a day every 8 hours. Level still low but they think this will work for our purposes.
I was just trying to find some information about this whole deal... I also seem to get lumps at injection site and sometimes it turns white. I am no longer injecting in thighs (due to very increased lumpy appearance) and only inject in abdomen now. I feel very bloated and my stomach feels just full of fluid, I am hoping this is normal!
The lumps that you are getting at the injection site are normal, they are called hematomas. The thigh is a tough area I have found since you tend to have more muscles in this area opposed to your abdomen. I would stick with you abdomen and make sure to rotate the injection on each side. It is going to be difficult since you are injecting 3x/day. You may need to have you significant other inject you in your abdominal area on your back. You can also inject yourself in the high buttocks area as well.
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What I don't understand is why they are using heparin for your injections. Heparin has a very quick "elimination" or "clearance rate". This is known as a medications "half-life". This means that your body removes it from your system in about 1.5 hours on average. It can be removed even quicker. So at 1.5 hr after your injection, you would have 5,000 units, 3 hrs 2,500, 4.5 hrs 1,250, 6 hrs 625, 7.5 hrs 312.5. So you can see if your clearance rate is quicker you will not have any anticoagulation. You are already low at 3 hrs. I would ask them why they are not using Arixtra or Lovenox. The elimination of Arixtra on average is 17 to 21 hours. The elimination of Lovenox on average is 7 hours with anticoagulant activity in your plasma for about 12 hours based on 1 injection a day. I have not found anything in the literature that suggests that either of these drugs would affect the IVF process and they don't effect development or cause toxicity. If it does, I would ask them to provide you a copy of the study(s). Please let me know if you get these copies as I would be interested in reading them as well. Neither of these drugs crosses the placenta so that is not a problem either once you get pregnant. You may need to get a Hematologist involved in this process.