I just come off cymbalta and my doctor has put me on prozac 20mg daily. The cymbalta worked wonders. I've been on the prozac for only four days, and yesterday was one of the worst days I can remember in awhile. My anxiety, ocd, irritability and whatever else has been awful. I know it takes awhile to regulate, but after yesterday I was ready to all my doctor and tell her something was bad wrong. Help!