How long does it take for your body to adjust to the pills? I am almost done with my first pack and I'm not sure if I'm experiencing side effects from the pills or from other things going on in my life. (ie. migranes, stress, depression, and increased appetite). In the first month I had random spotting which wasn't a big deal I had one day of severe cramping thought my appendix was gonna burst but that ceased the next day. I haven't noticed any help with acne - kind of bummed about that but I am taking minocycline (acne medication) to help but that lessens the effectiveness of the birth control. Should I wait it out and see if loestrin helps?