Am taking 25-100 Sinemet tabs TID for Parkinson's disease but begin "shuffling" gait after only 3-4 hours. I have been daignosed x 3 yrs. Am a caretaker for my 90 yr old mother and need to be able to function. I have no support system. I worry about eventual tardive dyskinesia, but my biggest worry is taking care of my mother and myself. The shuffling gait is unbearable. I feel like my feet are nailed to the floor and "gait" becomes a misnomer. I can't move. "Paralysis" would better describe my "gait". I have medicare and a good HMO plan. I was previously on Mirapex but developed painful muscle problems. Have been on Sinemet about 3 months. Have wondered if P.T. would help. Or maybe a case manager. Perhaps counselling from an R.D as to dietary do's and don'ts related to use of sinemet, plasma peaks etc. Thanks.
Is there a solution to the benefits of Sinemet wearing off in 3-4 hours?
- Posted:
- 19 Sep 2011 by Guinivere
- Topics:
- sinemet, parkinson's disease
Answers (2)
19 Sep 2011
I started off on Sinment 2 yrs ago, dosage was 25-100. Then after several months they uped my dose to 25-250. 2 months ago my neuro put me on Azilect and it seems to be helping. It sounds like to me that you are more advanced with Parkinsons then I am. I take Mirapex at night for the "squirmies" in my leg, mirapex will make muscles sore and I dont like that. So far I only have this problem on my right side.
Please go see a Neurologist and tell them your concerns. I know the frustration you have with movement because at times I feel like I am dragging a leg. Im sorry Im not much help. But I am here if you need to talk
20 Sep 2011
You need to talk with your neurologist again.
It is common that at certain points during the day, the helpful effects of the medication wear off, and symptoms can return.
Your doctor may need to change the type of medication, dose, amount of time between doses and how the medications are taken. There are many options available and often as your symptoms change, or new problems arise, your treatment should be reviewed.
http://www.drugs.com/enc/parkinson-s-disease.html
Search for questions
Still looking for answers? Try searching for what you seek or ask your own question.
Similar questions
Can I take my Sinement CR tabs perscribed 3 times a day TO WORK EVENLY DURING MY DAYTIME HOURS?
Can I take Sinemet CR 3 times Daily ..8am, 12noon & 5pm to get most for my awaken hours,or does Sinement CR have to be though a 24 hr spread ...
Levothyroxine and Parkinson's drugs such as Sinemet?
What does it mean when it says here that there is a "POSSIBLE" drug interaction when taking Levothyroxine (lowest dose) and Sinemet (25/100 ...
Sinemet price?
need to get medication for my dad at a lower price ... seeking discounted sinemet

Suzanne 66 - Thanks so much for responding. I appreciate your remarks and am beginning to see the truth of what you are saying. I will call him this week and see what can be done. Mu current situation is at times scary and often embarrassing. Thanks again.