Is it safe to take Depakote ER 1500 mg and Seroquel 800 mg?

Hello,

Interactions between your selected drugs

divalproex sodium ↔ quetiapine
Applies to: Depakote ER (divalproex sodium), Seroquel (quetiapine)
MONITOR: Central nervous system- and/or respiratory-depressant effects may be additively or synergistically increased in patients taking multiple drugs that cause these effects, especially in elderly or debilitated patients.

MANAGEMENT: During concomitant use of these drugs, patients should be monitored for potentially excessive or prolonged CNS and respiratory depression. Ambulatory patients should be counseled to avoid hazardous activities requiring mental alertness and motor coordination until they know how these agents affect them, and to notify their physician if they experience excessive or prolonged CNS effects that interfere with their normal activities.

Other drugs that your selected drugs interact with

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Depakote ER (divalproex sodium) interacts with more than 200 other drugs.
Seroquel (quetiapine) interacts with more than 400 other drugs.

Interactions between your selected drugs and food

No results found - however, this does not necessarily mean no interactions exist. ALWAYS consult with your doctor or pharmacist.

http://www.drugs.com/interactions-check.php?drug_list=918-483,1979-1274

I also take these medications , have been on them for some time, and have had no problems, but that is me. Now we are all unique and medications or in this case interactions may affect me differently than it may affect you or someone else. Not all organisms react in the same way to medications and everyhting that comes with them, benefits, risks, interactions,etc.
Having said that if you feel something is not right, contact your Dr. right away or seek immediate medical attention ASAP.-
I do not mean to scare you but it is always good to know that there might be a possibility of something not working properly so you are prepared to act fast and reverse the situation.-

All the best.-