I have taken opana in past. Still have plenty left over. I ran out of my oxycodone 10 mgs and surg in 4days. So i took 10 mgs of oxy at 8 and 12. Than i took 10 mgs of opana er at 1:30 and 2.30 because i meant to take two. Will spacing them hurt me?. Its a little too late!