This question has also been asked and answered here: Can Actemra cause Hair Loss?
8 Jul 2010
Hi , yes (frequent side efect) loss or thinning of hair
I know you this... but in order to help you i also need to know-ok
BRAND NAME: Arava
DRUG CLASS AND MECHANISM: Leflunomide is an oral, disease-modifying drug that is used in the treatment of rheumatoid arthritis. Leflunomide reduces inflammation in the joints that is responsible for both the symptoms of rheumatoid arthritis and the destruction of joints. This reduces symptoms as well as the progressive deformities of the joints caused by the arthritis. Leflunomide reduces inflammation by suppressing the activity of immune cells responsible for the inflammation. Leflunomide suppresses immune cells by inhibiting dihydroorotate dehydrogenase, an enzyme that is necessary for the production of DNA and RNA. Without DNA and RNA the immune cells (and most other types of cells) cannot multiply or function (or exist). Because of its unique and different mechanism of action, leflunomide is of value when added to other medications used for treating rheumatoid arthritis. Leflunomide was approved by the FDA in September, 1998.
SIDE EFFECTS: The most frequently reported side effects are diarrhea, nausea, headache, rash, itching, loss or thinning of hair and weight loss. Leflunomide also may cause high blood pressure, chest pain and abnormal heartbeats. Since leflunomide suppresses the immune system, it may increase the risk to patients of infections. The most frequently reported infections involve the respiratory tract. Leflunomide may cause abnormal liver tests in the blood, suggesting damage to the liver. The liver tests usually return to normal with continued treatment. The dose of leflunomide should be reduced if liver tests are persistently greater than twice the upper limit of normal, and leflunomide should be discontinued if the levels remain above three times the upper limit of normal despite a reduction in dose. Leflunomide should not be administered to individuals with liver problems.
Contact your Doctor there might be something you can do about it... from a caring individual
21 Oct 2012
One of the side effects listed for Arava is hair loss. I've been on Arava for about 2 1/2 years and at first my hair was falling out very badly! Now it seems to have slowed down a lot. I'm a women so this was very upsetting but my hair has been growing back in. Still on Arava.
- Arava Information for Consumers
- Arava Information for Healthcare Professionals (includes dosage details)
- Side Effects of Arava (detailed)
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