Is edema of the extremities and mouth, a posssible side effect of taking Sucralfate?

Swelling of the mouth could be a sign of an allergy and should be reported to your doctor immediately.

You will find information on sucralfate side effects at http://www.drugs.com/sfx/sucralfate-side-effects.html

Side Effects of Sucralfate - for the Consumer
Sucralfate

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Sucralfate:

Constipation; dizziness; feeling of a whirling motion.

Seek medical attention right away if any of these SEVERE side effects occur when using Sucralfate:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue).