Is Depakote Sprinkles an extended release or a regular release like the DR?

10 Oct 2010

I haven't read the information on all the websites but from my understanding of the way these tablets/capsule are made I am giving my opinion.

Yes, the ER tablets should not be broken ... because this would cause dumping of the whole dose and it won't give an extended release profile.

They recommend that capsules should not be opened ... perhaps to avoid the risk of losing out on some medicine. But if you can't swallow the capsule you could open the capsule and take the sprinkles mixed with food. These sprinkles have a special coating as well and that's why they say not to chew the sprinkles, otherwise the coating is disturbed and the medicine will come out all at once.

http://www.drugs.com/cons/depakote-sprinkles.html